Brief Information of the Cell Line and Protein
Cell Line ID: CL000083 , MCF-7
Synonyms
MCF 7
MCF.7
MCF7
Michigan Cancer Foundation-7
ssMCF-7
ssMCF7
MCF7/WT
MCF7-CTRL
IBMF-7
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Protein ID: PT02791 , Hypoxia-inducible factor 1-alpha
Gene Name HIF1A
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q16665
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000083  Protein ID: PT02791
 
Compound ID Compound Name Compound Formula
CP0437196
ethyl 5-[(3,4-dimethoxyphenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C20H21NO7S
 2
1
IC50 = 12500 nM
   TI
   LI
   LO
   TS
2
IC50 = 18800 nM
   TI
   LI
   LO
   TS
CP0409462
ethyl 5-[(2,5-dimethoxyphenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C20H21NO7S
 1
1
IC50 = 15500 nM
   TI
   LI
   LO
   TS
CP0483565
ethyl 3-methyl-5-[[2-(trifluoromethyl)phenyl]sulfonylamino]-1-benzofuran-2-carboxylate
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C19H16F3NO5S
 1
1
IC50 = 16500 nM
   TI
   LI
   LO
   TS
CP0565161
ethyl 3-methyl-5-[(2-methylphenyl)sulfonylamino]-1-benzofuran-2-carboxylate
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C19H19NO5S
 1
1
IC50 = 19400 nM
   TI
   LI
   LO
   TS
CP0451689
ethyl 5-[(2-bromophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16BrNO5S
 1
1
IC50 = 19900 nM
   TI
   LI
   LO
   TS
CP0507152
4-[(2S)-2-amino-2-carboxyethyl]-N,N-bis(2-chloroethyl)benzeneamine oxide;dihydrochloride
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C13H20Cl4N2O3
 1
1
IC50 = 20200 nM
   TI
   LI
   LO
   TS
CP0483564
ethyl 5-[(2-chlorophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16ClNO5S
 1
1
IC50 = 20800 nM
   TI
   LI
   LO
   TS
CP0483566
ethyl 3-methyl-5-(naphthalen-2-ylsulfonylamino)-1-benzofuran-2-carboxylate
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C22H19NO5S
 1
1
IC50 = 22600 nM
   TI
   LI
   LO
   TS
CP0409460
ethyl 3-methyl-5-[(2-nitrophenyl)sulfonylamino]-1-benzofuran-2-carboxylate
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C18H16N2O7S
 1
1
IC50 = 24400 nM
   TI
   LI
   LO
   TS
CP0547746
ethyl 5-[(3-bromophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16BrNO5S
 1
1
IC50 = 25600 nM
   TI
   LI
   LO
   TS
CP0507151
ethyl 5-[(4-tert-butylphenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C22H25NO5S
 1
1
IC50 = 27100 nM
   TI
   LI
   LO
   TS
CP0454841
ethyl 3-methyl-5-[(3-nitrophenyl)sulfonylamino]-1-benzofuran-2-carboxylate
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C18H16N2O7S
 1
1
IC50 = 29400 nM
   TI
   LI
   LO
   TS
CP0454827
ethyl 5-[(4-bromophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16BrNO5S
 1
1
IC50 = 29900 nM
   TI
   LI
   LO
   TS
CP0479885
ethyl 3-methyl-5-[(3-methylphenyl)sulfonylamino]-1-benzofuran-2-carboxylate
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C19H19NO5S
 1
1
IC50 = 32700 nM
   TI
   LI
   LO
   TS
CP0454842
ethyl 3-methyl-5-(pyridin-3-ylsulfonylamino)-1-benzofuran-2-carboxylate
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C17H16N2O5S
 1
1
IC50 = 34100 nM
   TI
   LI
   LO
   TS
CP0547747
ethyl 3-methyl-5-[(4-nitrophenyl)sulfonylamino]-1-benzofuran-2-carboxylate
   Show/Hide
C18H16N2O7S
 1
1
IC50 = 36200 nM
   TI
   LI
   LO
   TS
CP0565162
ethyl 3-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylamino]-1-benzofuran-2-carboxylate
   Show/Hide
C19H16F3NO5S
 1
1
IC50 = 36300 nM
   TI
   LI
   LO
   TS
CP0547745
ethyl 5-[(3-chlorophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16ClNO5S
 1
1
IC50 = 36600 nM
   TI
   LI
   LO
   TS
CP0454812
ethyl 3-methyl-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]-1-benzofuran-2-carboxylate
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C19H16F3NO5S
 1
1
IC50 = 41700 nM
   TI
   LI
   LO
   TS
CP0411214
ethyl 3-methyl-5-(thiophen-2-ylsulfonylamino)-1-benzofuran-2-carboxylate
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C16H15NO5S2
 1
1
IC50 = 45400 nM
   TI
   LI
   LO
   TS
CP0454826
ethyl 3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-benzofuran-2-carboxylate
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C19H19NO5S
 1
1
IC50 = 45400 nM
   TI
   LI
   LO
   TS
CP0437195
ethyl 5-[(4-chlorophenyl)sulfonylamino]-3-methyl-1-benzofuran-2-carboxylate
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C18H16ClNO5S
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS