Brief Information of the Cell Line and Protein
Cell Line ID: CL000083 , MCF-7
 Cell Line Info 
Synonyms
MCF 7
MCF.7
MCF7
Michigan Cancer Foundation-7
ssMCF-7
ssMCF7
MCF7/WT
MCF7-CTRL
IBMF-7
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Protein ID: PT01500 , Heat shock protein HSP 90-alpha
 Protein Info 
Gene Name HSP90AA1
Organism Homo sapiens, Human
Protein Classification Other cytosolic protein
Uniprot ID P07900
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000083
 Cell Line Info 
 Protein ID: PT01500
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0036286
 Compound Info 
5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide
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C26H31N3O5
  1
1
EC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0301980
 Compound Info 
4-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]but-3-yn-1-ol
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C19H20ClN5O2
  1
1
EC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0054776
 Compound Info 
BMS-722782
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C31H43N3O8
  1
1
EC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247725
 Compound Info 
5-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]-2-methylpent-4-yn-2-ol
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C21H24ClN5O2
  1
1
EC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0144005
 Compound Info 
3-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]prop-2-yn-1-ol
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C18H18ClN5O2
  1
1
EC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0057361
 Compound Info 
4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-hydroxycyclohexyl)amino]benzamide
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C23H27F3N4O3
  1
1
EC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0204312
 Compound Info 
4-chloro-5-ethynyl-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-2-amine
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C17H16ClN5O
  1
1
EC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0204311
 Compound Info 
3-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]propan-1-ol
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C18H22ClN5O2
  1
1
EC50 = 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060369
 Compound Info 
2-amino-6-halopurine analogue, 20
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C14H15ClN6O
  1
1
EC50 = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573235
 Compound Info 
4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-2-amine
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C15H16ClN5O
  1
1
EC50 = 98 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0270352
 Compound Info 
4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-5-phenylpyrrolo[2,3-d]pyrimidin-2-amine
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C21H20ClN5O
  1
1
EC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS