| Compound ID |
Compound Name |
Compound Formula |
|
CP0362338
|
1-[(3S,5R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-3,5-dimethylpiperazin-1-yl]ethanone
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|
C27H37N7O3
|
1
|
| 1 |
IC50 = 1.585 nM
|
|
|
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CP0213781
|
(3R)-4-[[1-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenyl]azetidin-3-yl]methyl]-1,3-dimethylpiperazin-2-one
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|
C27H36N8O2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
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CP0213780
|
(3R)-4-[4-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]butyl]-1,3-dimethylpiperazin-2-one
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|
C27H37N7O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
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CP0362373
|
(3R,5R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3,5-trimethylpiperazin-2-one
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|
C26H35N7O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
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CP0368533
|
(3R)-4-[3-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]propyl]-1,3-dimethylpiperazin-2-one
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|
C26H35N7O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0143638
|
(3R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one
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|
C25H33N7O3
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0249898
|
(3R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenyl]ethyl]-1,3-dimethylpiperazin-2-one
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|
C25H33N7O2
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0480263
|
(3R)-1,3-dimethyl-4-[2-[4-[1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C25H30F3N7O2
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
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CP0213782
|
(3R)-1,3-dimethyl-4-[2-[4-[1-(3-methylsulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C25H33N7O2S
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0236893
|
(3R)-4-[2-[4-[1-(3-chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one
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|
C24H30ClN7O2
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0259597
|
(3R)-1,3-dimethyl-4-[2-[4-[1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C25H33N7O2
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
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CP0362339
|
1-[(2S,6R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-2,6-dimethylpiperazin-1-yl]ethanone
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|
C27H37N7O3
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0236899
|
(3R)-4-[2-[4-[1-[3-(dimethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one
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|
C26H36N8O2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0245134
|
(3R)-4-[1-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenyl]piperidin-4-yl]-1,3-dimethylpiperazin-2-one
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|
C28H38N8O2
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0191020
|
(3S)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one
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|
C25H33N7O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0213778
|
1-methyl-4-[2-[4-[1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C24H28F3N7O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0249897
|
1-[4-[2-[4-[1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-1-yl]ethanone
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|
C25H30F3N7O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
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CP0480262
|
(3R)-4-[1-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenyl]azetidin-3-yl]-1,3-dimethylpiperazin-2-one
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|
C26H34N8O2
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
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CP0364436
|
4-methyl-1-[2-[4-[1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C24H28F3N7O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0180784
|
(3R)-1,3-dimethyl-4-[2-[4-[1-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]piperazin-2-one
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|
C24H31N7O2
|
1
|
| 1 |
IC50 > 3162.28 nM
|
|
|
