Brief Information of the Cell Line and Protein
Cell Line ID: CL000068 , A-549
 Cell Line Info 
Synonyms
A 549
A549
NCI-A549
A549/ATCC
A549 ATCC
A549ATCC
hA549
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0023
Protein ID: PT03087 , Protein arginine N-methyltransferase 5
 Protein Info 
Gene Name PRMT5
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O14744
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000068
 Cell Line Info 
 Protein ID: PT03087
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0010708
 Compound Info 
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(1,8-diazaspiro[4.5]decan-1-ylmethyl)oxolane-3,4-diol
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C19H28N6O3
  1
1
IC50 = 58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0005352
 Compound Info 
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(8-methyl-1,8-diazaspiro[4.5]decan-1-yl)methyl]oxolane-3,4-diol
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C20H30N6O3
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012418
 Compound Info 
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(1,8-diazaspiro[4.5]decan-1-ylmethyl)oxolane-3,4-diol
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C18H27N7O3
  1
1
IC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014390
 Compound Info 
(2R,3S,4R,5R)-2-[[(2S)-2-(2-aminoethyl)pyrrolidin-1-yl]methyl]-5-(6-aminopurin-9-yl)oxolane-3,4-diol
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C16H25N7O3
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012651
 Compound Info 
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(pyrrolidin-1-ylmethyl)oxolane-3,4-diol
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C14H20N6O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0013286
 Compound Info 
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(1-azaspiro[4.5]decan-1-ylmethyl)oxolane-3,4-diol
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C19H28N6O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014795
 Compound Info 
1-[1-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-1,8-diazaspiro[4.5]decan-8-yl]ethanone
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C20H29N7O4
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS