Brief Information of the Cell Line and Protein
Cell Line ID: CL000068 , A-549
Synonyms
A 549
A549
NCI-A549
A549/ATCC
A549 ATCC
A549ATCC
hA549
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0023
Protein ID: PT00838 , NAD(P)H dehydrogenase [quinone] 1
Gene Name NQO1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P15559
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000068  Protein ID: PT00838
 
Compound ID Compound Name Compound Formula
CP0456142
2,2-dimethyl-3-[3-[1-(phenylselanylmethyl)triazol-4-yl]anilino]-3H-benzo[g][1]benzofuran-4,5-dione
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C29H24N4O3Se
 2
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0503890
2,2-dimethyl-3-[4-(phenylselanylmethyl)triazol-1-yl]-3H-benzo[g][1]benzofuran-4,5-dione
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C23H19N3O3Se
 2
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0522655
3-(4-fluoro-3-nitroanilino)-2,2-dimethyl-3H-benzo[g][1]benzofuran-4,5-dione
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C20H15FN2O5
 2
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0503889
2,2-dimethyl-3-(4-nitroanilino)-3H-benzo[g][1]benzofuran-4,5-dione
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C20H16N2O5
 2
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0398276
3-(4-methoxy-2-nitroanilino)-2,2-dimethyl-3H-benzo[g][1]benzofuran-4,5-dione
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C21H18N2O6
 2
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0427329
2,2-dimethyl-3-(3-nitroanilino)-3H-benzo[g][1]benzofuran-4,5-dione
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C20H16N2O5
 2
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
2
IC50 > 3200 nM
   TI
   LI
   LO
   TS
CP0393114
3,6,9-trimethylbenzo[g][1]benzofuran-4,5-dione
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C15H12O3
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0049432
β-Lapachone (A3)
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C15H14O3
 3
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
2
IC50 = 3400 nM
   TI
   LI
   LO
   TS
3
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0393954
7,8-dimethylbenzo[g][1]benzofuran-4,5-dione
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C14H10O3
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0517956
3-ethyl-7-methylbenzo[g][1]benzofuran-4,5-dione
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C15H12O3
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0393115
3,7,8-trimethylbenzo[g][1]benzofuran-4,5-dione
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C15H12O3
 1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0476132
3,8-dimethylbenzo[g][1]benzofuran-4,5-dione
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C14H10O3
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0147298
8-methoxy-2,3,3-trimethyl-2H-benzo[g][1]benzofuran-4,5-dione
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C16H16O4
 1
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
CP0393953
3,7-dimethylbenzo[g][1]benzofuran-4,5-dione
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C14H10O3
 1
1
IC50 = 8500 nM
   TI
   LI
   LO
   TS
CP0053557
9-methoxy-2,3,3-trimethyl-2H-benzo[g][1]benzofuran-4,5-dione
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C16H16O4
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0404787
3-ethyl-7,8-dimethylbenzo[g][1]benzofuran-4,5-dione
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C16H14O3
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0147297
7-methoxy-2,3,3-trimethyl-2H-benzo[g][1]benzofuran-4,5-dione
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C16H16O4
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS