Brief Information of the Cell Line and Protein
Cell Line ID: CL000065 , HEK293-EBNA
 Cell Line Info 
Synonyms
293 c18
293c18
HEK 293 c18
HEK-293 c18
HEK293-EBNA1
HEK-293-EBNA
HEK 293-EBNA
HEK 293 EBNA
HEK293EBNA
293 EBNA
293-EBNA1
293-EBNA
293/EBNA
293EBNA
EBNA-293
EBNA293
293E
HEK293E
HEK/EBNA
HEK-EBNA
HEK.EBNA
293/EBNA-1
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6974
Protein ID: PT01786 , Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
 Protein Info 
Gene Name ENPP2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q13822
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000065
 Cell Line Info 
 Protein ID: PT01786
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0529924
 Compound Info 
US20230312582, Example Control
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C21H23N7O2
  1
1
IC50 < 1.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0554648
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-(2H-triazol-4-yl)pentan-1-one
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C23H27N7O
  1
1
IC50 = 2.2 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0539706
 Compound Info 
6-[3-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]propanoyl]-3H-1,3-benzoxazol-2-one
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C26H25N5O3
  1
1
IC50 = 2.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0529925
 Compound Info 
6-[3-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-3-oxopropyl]-3H-1,3-benzoxazol-2-one
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C26H25N5O3
  1
1
IC50 = 2.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557680
 Compound Info 
6-[3-[2-[2-(4-chlorophenyl)ethylamino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-3-oxopropyl]-3H-1,3-benzoxazol-2-one
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C25H24ClN5O3
  1
1
IC50 = 4 nM
 Bioactivity Info 
   TI
   LI
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CP0539705
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-imidazol-1-ylpentan-1-one
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C24H28N6O
  1
1
IC50 = 4.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0224657
 Compound Info 
(3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate
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C22H21Cl2N3O5
  1
1
IC50 = 8.4 nM
 Bioactivity Info 
   TI
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CP0534534
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-(1H-imidazol-5-yl)pentan-1-one
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C24H28N6O
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564597
 Compound Info 
6-[3-oxo-3-[2-(4-propan-2-yloxyanilino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]propyl]-3H-1,3-benzoxazol-2-one
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C26H27N5O4
  1
1
IC50 = 19.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440077
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-(2H-tetrazol-5-yl)pentan-1-one
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C22H26N8O
  1
1
IC50 = 24 nM
 Bioactivity Info 
   TI
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CP0554695
 Compound Info 
6-[3-[2-[(3-chlorophenyl)methylamino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-3-oxopropyl]-3H-1,3-benzoxazol-2-one
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C24H22ClN5O3
  1
1
IC50 = 52.3 nM
 Bioactivity Info 
   TI
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CP0542532
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-(1H-1,2,4-triazol-5-yl)pentan-1-one
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C23H27N7O
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
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CP0421313
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-(1H-pyrazol-5-yl)pentan-1-one
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C24H28N6O
  1
1
IC50 = 123 nM
 Bioactivity Info 
   TI
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CP0561452
 Compound Info 
1-[2-(2,3-dihydro-1H-inden-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]ethanone
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C18H20N4O
  1
1
IC50 = 520 nM
 Bioactivity Info 
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