Brief Information of the Cell Line and Protein
Cell Line ID: CL000065 , HEK293-EBNA
Synonyms
293 c18
293c18
HEK 293 c18
HEK-293 c18
HEK293-EBNA1
HEK-293-EBNA
HEK 293-EBNA
HEK 293 EBNA
HEK293EBNA
293 EBNA
293-EBNA1
293-EBNA
293/EBNA
293EBNA
EBNA-293
EBNA293
293E
HEK293E
HEK/EBNA
HEK-EBNA
HEK.EBNA
293/EBNA-1
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6974
Protein ID: PT01282 , Hydroxycarboxylic acid receptor 2
Gene Name HCAR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q8TDS4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000065  Protein ID: PT01282
 
Compound ID Compound Name Compound Formula
CP0403622
2-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]benzoic acid
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C20H16ClNO4
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0403637
1-butyl-4-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]pyrrole-3-carboxylic acid
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C22H23ClN2O4
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0568832
1-butyl-4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C19H21N5O5
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0559920
1-ethyl-4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C18H18N4O5
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0517784
1-butyl-3-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]pyrazole-4-carboxylic acid
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C21H22ClN3O4
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0553159
1-butyl-4-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]-5-oxo-2H-pyrrole-3-carboxylic acid
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C22H23ClN2O5
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0562758
1-butyl-4-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]pyrazole-3-carboxylic acid
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C21H22ClN3O4
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0037107
hydron;pyridine-3-carboxylate
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C6H5NO2
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0403617
4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-methylpyrrole-3-carboxylic acid
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C17H16N4O5
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0552887
1-benzyl-4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C23H20N4O5
 1
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
CP0561874
1-(3-fluoropropyl)-4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C18H18FN5O5
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0511356
4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-methylpyrrole-3-carboxylic acid
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C16H15N5O5
 1
1
IC50 = 970 nM
   TI
   LI
   LO
   TS
CP0520850
4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-(3-methoxypropyl)pyrrole-3-carboxylic acid
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C19H21N5O6
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0540537
1-cyclopropyl-4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C18H17N5O5
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0526900
5-butyl-3-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]-1H-pyrrole-2-carboxylic acid
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C22H23ClN2O4
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0520851
4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-propan-2-ylpyrrole-3-carboxylic acid
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C18H19N5O5
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0520852
1-(3-hydroxypropyl)-4-[3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C18H19N5O6
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0517761
2-butyl-5-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]-3-methylimidazole-4-carboxylic acid
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C22H24ClN3O4
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0540536
1-[3-(5-chloro-6-hydroxynaphthalen-2-yl)propanoylamino]pyrrole-2-carboxylic acid
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C18H15ClN2O4
 1
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0473425
1-(2-hydroxyethyl)-4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]pyrrole-3-carboxylic acid
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C18H18N4O6
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0525441
4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-(pyridin-4-ylmethyl)pyrrole-3-carboxylic acid
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C22H19N5O5
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0473426
4-[3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanoylamino]-1-(2-morpholin-4-ylethyl)pyrrole-3-carboxylic acid
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C22H25N5O6
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS