| Compound ID |
Compound Name |
Compound Formula |
|
CP0487942
|
4-(1-benzothiophen-6-yl)-2-methyl-3,4-dihydro-1H-isoquinoline
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|
C18H17NS
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0862386
|
(+/-)-4-(1H-indol-5-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
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|
C18H18N2
|
2
|
| 1 |
IC50 = 4.5 nM
|
|
|
| 2 |
Ki = 3.8 nM
|
|
|
|
CP0382561
|
US9085531, 102
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|
C21H24N2S
|
2
|
| 1 |
IC50 = 5.3 nM
|
|
|
| 2 |
Ki = 4.4 nM
|
|
|
|
CP0396823
|
US9085531, 14
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|
C18H17NO
|
2
|
| 1 |
IC50 = 5.7 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0411811
|
4-(1-benzothiophen-5-yl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Show/Hide
|
C18H17NOS
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0396824
|
US9085531, 17
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|
C18H17NO
|
2
|
| 1 |
IC50 = 7.5 nM
|
|
|
| 2 |
Ki = 7.5 nM
|
|
|
|
CP0105627
|
4-(1-benzothiophen-5-yl)-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C19H19NOS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0411812
|
[4-(1-benzothiophen-5-yl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]methanamine
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|
C19H20N2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0140304
|
4-(1-benzothiophen-5-yl)-2,7-dimethyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C19H19NS
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0384782
|
US9085531, 2
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|
C18H17NO
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0407606
|
US9085531, 21
Show/Hide
|
C18H17NS
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0414291
|
4-(1-benzofuran-4-yl)-2-methyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C18H17NO
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0488293
|
4-(1-benzofuran-3-yl)-2-methyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C18H17NO
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0494543
|
4-[4-(1-benzothiophen-6-yl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]morpholine
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|
C22H24N2OS
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0105628
|
US9085531, 40
Show/Hide
|
C18H17NS
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0409636
|
BDBM50054534
Show/Hide
|
C18H17NS
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0379916
|
BDBM50054527
Show/Hide
|
C23H26N2S
|
2
|
| 1 |
IC50 = 570 nM
|
|
|
| 2 |
Ki = 460 nM
|
|
|
|
CP0536634
|
2-[[4-(1-benzothiophen-5-yl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]amino]ethanol
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|
C20H22N2OS
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0414289
|
US9085531, 19
Show/Hide
|
C18H17NO
|
2
|
| 1 |
IC50 > 300 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0415903
|
US9085531, 97
Show/Hide
|
C22H19N3S
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0867810
|
US9085531, 125
Show/Hide
|
C17H16ClN3
|
1
|
| 1 |
Ki = 11.5 nM
|
|
|
|
CP0857555
|
(+)-4-(1H-indol-6-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C18H18N2
|
1
|
| 1 |
Ki = 19.8 nM
|
|
|
|
CP0857556
|
(+)-4-(1H-indazol-5-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C17H17N3
|
1
|
| 1 |
Ki = 29.4 nM
|
|
|
|
CP0468434
|
US9085531, 71
Show/Hide
|
C22H19N3S
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0287226
|
methyl 2-phenyl-2-piperidin-2-ylacetate
Show/Hide
|
C14H19NO2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0407673
|
US9085531, 78
Show/Hide
|
C23H26N2OS
|
1
|
| 1 |
Ki = 35.4 nM
|
|
|
|
CP0474037
|
4-(4-fluorophenyl)-2,7-dimethyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C17H18FN
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0396822
|
BDBM50054516
Show/Hide
|
C17H16N2S
|
1
|
| 1 |
Ki = 36.5 nM
|
|
|
|
CP0458987
|
US9085531, 73
Show/Hide
|
C22H19N3S
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0554208
|
US9085531, 56
Show/Hide
|
C21H21N
|
1
|
| 1 |
Ki = 39.5 nM
|
|
|
|
CP0538925
|
US9085531, 117
Show/Hide
|
C22H19N3O
|
1
|
| 1 |
Ki = 41.3 nM
|
|
|
|
CP0389390
|
US9085531, 100
Show/Hide
|
C22H24N2OS
|
1
|
| 1 |
Ki = 53.4 nM
|
|
|
|
CP0545728
|
US9085531, 137
Show/Hide
|
C24H21N3
|
1
|
| 1 |
Ki = 59.7 nM
|
|
|
|
CP0538207
|
US9085531, 135
Show/Hide
|
C17H16N2S
|
1
|
| 1 |
Ki = 79.4 nM
|
|
|
|
CP0483271
|
US9085531, 142
Show/Hide
|
C25H28N2O
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0859202
|
US9085531, 130
Show/Hide
|
C18H19N3
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0416412
|
US9085531, 70
Show/Hide
|
C22H19N3S
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0459699
|
BDBM50054521
Show/Hide
|
C22H24N2OS
|
1
|
| 1 |
Ki = 284 nM
|
|
|
|
CP0863203
|
(+)-4-(1H-indazol-6-yl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C17H17N3
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0403475
|
US9085531, 4-methyl-thiophen-2-yl
Show/Hide
|
C15H17NS
|
1
|
| 1 |
Ki = 2250 nM
|
|
|
|
CP0431464
|
US9085531, 6-methoxy-pyridin-3-yl
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
Ki = 2787 nM
|
|
|
|
CP0413981
|
US9085531, 5-methyl-furan-2-yl
Show/Hide
|
C15H17NO
|
1
|
| 1 |
Ki = 5640 nM
|
|
|
|
CP0463174
|
US9085531, thiophen-2-yl
Show/Hide
|
C14H15NS
|
1
|
| 1 |
Ki = 5990 nM
|
|
|
|
CP0407192
|
US9085531, 11
Show/Hide
|
C19H19NO2
|
1
|
| 1 |
Ki > 300 nM
|
|
|
|
CP0409884
|
US9085531, 82
Show/Hide
|
C19H19NOS
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0429723
|
US9085531, 84
Show/Hide
|
C24H23N3OS
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
