Brief Information of the Cell Line and Protein
Cell Line ID: CL000059 , HuT 78
Synonyms
Hut 78
HUT 78
HuT-78
HUT-78
HuT78
Hut78
HUT78
NCI-H78
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0337
Protein ID: PT01462 , Bromodomain-containing protein 4
Gene Name BRD4
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O60885
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000059  Protein ID: PT01462
 
Compound ID Compound Name Compound Formula
CP0717935
rac-8-(((3R,4R)-3-((1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-methoxy)piperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)quinolin-2(1H)-one
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C27H34N4O4S
 1
1
Kd = 1258.93 nM
   TI
   LI
   LO
   TS
CP0199056
8-[[(3R,4R)-3-(cyclohexylmethoxy)piperidin-4-yl]amino]-3-methyl-5-(5-methylpyridin-3-yl)-1H-1,7-naphthyridin-2-one
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C27H35N5O2
 1
1
Kd = 1584.89 nM
   TI
   LI
   LO
   TS
CP0651910
8-(((3R,4R)-3-((1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-methoxy)-1-methylpiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one
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C27H35N5O4S
 1
1
Kd = 19952.62 nM
   TI
   LI
   LO
   TS