| Compound ID |
Compound Name |
Compound Formula |
|
CP0331627
|
1-phenyl-8-(1-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H31N3O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0453139
|
1-phenyl-8-((cis,1R,2R)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H31N3O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0077854
|
1-Phenyl-8-((cis,1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H31N3O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0441519
|
1-(4-chloro-phenyl)-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H30ClN3O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0103598
|
8-((cis, rac)-2-hydroxy-2-o-tolyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C26H33N3O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0146215
|
1-phenyl-8-((trans, rac)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H31N3O
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0277722
|
8-((cis, rac)-2-hydroxy-2-pyridin-4-yl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H30N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0058985
|
(S)-4-(4-fluoro-phenyl)-8-[(1R,2R)-2-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
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|
C26H30F2N2O
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
|
CP0078022
|
8-[(cis, rac)-2-(3-chloro-phenyl)-2-hydroxy-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H30ClN3O2
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
|
CP0103402
|
8-((cis, rac)-2-hydroxy-2-pyridin-2-yl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H30N4O2
|
1
|
| 1 |
IC50 = 1420 nM
|
|
|
|
CP0186323
|
(S)-4-(4-fluoro-phenyl)-8-[(1S,2S)-2-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H30F2N2O
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
|
CP0046134
|
8-((trans, rac)-2-hydroxy-2-phenyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C25H31N3O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0135237
|
8-((cis, rac)-2-hydroxy-2-pyridin-3-yl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H30N4O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0297177
|
8-[(cis, rac)-2-hydroxy-2-(3-methoxy-phenyl)-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C26H33N3O3
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0167089
|
1-(4-chloro-phenyl)-8-[(cis, rac)-2-(4-fluoro-phenyl)-2-hydroxy-cyclohexyl]-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H29ClFN3O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0432526
|
1-pentyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H37N3O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0277721
|
8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cyclohexyl]-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H29ClFN3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0135238
|
8-[(cis, rac)-2-hydroxy-2-(4-methoxy-phenyl)-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C26H33N3O3
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0255149
|
8-((cis, rac)-3-hydroxy-3-phenyl-tetrahydro-pyran-4-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C24H29N3O3
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0182472
|
8-((cis, rac)-2-hydroxy-2-phenyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H31N3O2
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0684132
|
8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4.5]decan-1-one
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|
C23H35ClN2O
|
1
|
| 1 |
IC50 = 2730 nM
|
|
|
|
CP0046108
|
8-((cis, rac)-2-hydroxy-2-p-tolyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C26H33N3O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0334146
|
8-[1-(4-fluorophenyl)cyclohexyl]-4-propyl-2,8-diazaspiro[4.5]decan-1-one
Show/Hide
|
C23H33FN2O
|
1
|
| 1 |
IC50 = 3030 nM
|
|
|
|
CP0432525
|
1-phenethyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one
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|
C27H35N3O
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0081540
|
(R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
IC50 = 3490 nM
|
|
|
|
CP0075650
|
8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0272339
|
8-[(cis, rac)-2-(3,4-dichloro-phenyl)-2-hydroxy-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H29Cl2N3O2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0108223
|
4-(4-fluorophenyl)-8-[1-(2-methylphenyl)cyclohexyl]-2,8-diazaspiro[4.5]decan-1-one
Show/Hide
|
C27H33FN2O
|
1
|
| 1 |
IC50 = 3851 nM
|
|
|
|
CP0058987
|
4-phenyl-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
IC50 = 3920 nM
|
|
|
|
CP0046120
|
1-(4-fluoro-phenyl)-8-[(cis, rac)-2-(4-fluoro-phenyl)-2-hydroxy-cyclohexyl]-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H29F2N3O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0302926
|
8-[(cis, rac)-2-(4-fluoro-phenyl)-2-hydroxy-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C25H30FN3O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0103401
|
8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cyclohexyl]-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C26H32ClN3O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0297132
|
8-((cis, rac)-4-hydroxy-4-phenyl-tetrahydro-pyran-3-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0364169
|
(R)-4-phenyl-8-((1R,2R)-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
IC50 = 5480 nM
|
|
|
|
CP0081536
|
(R)-4-(4-fluoro-phenyl)-8-[(1R,2R)-2-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H30F2N2O
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
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CP0180148
|
4-(4-fluorophenyl)-8-[1-(3-fluorophenyl)cyclohexyl]-2,8-diazaspiro[4.5]decan-1-one
Show/Hide
|
C26H30F2N2O
|
1
|
| 1 |
IC50 = 7180 nM
|
|
|
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CP0058984
|
(R)-4-(4-fluoro-phenyl)-8-[(1S,2S)-2-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H30F2N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0134842
|
(S)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0659598
|
4-(4-fluoro-phenyl)-8-[1-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H31F3N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
