Brief Information of the Cell Line and Protein
Cell Line ID: CL000051 , BHK-21
Synonyms
BHK 21
BHK21
Baby Hamster Kidney-21
Baby Hamster Kidney 21
Baby Hamster Kidney from litter No. 21
BHK
Category Spontaneously immortalized cell line
Organism
Mesocricetus auratus (Golden hamster)
Cellosaurus ID
CVCL_1914
Protein ID: PT00915 , Peroxisome proliferator-activated receptor gamma
Gene Name PPARG
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P37231
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000051  Protein ID: PT00915
 
Compound ID Compound Name Compound Formula
CP0386116
2-(hexyloxy)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C29H33NO5S
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0388724
(S)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-propoxypropanoic acid
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C26H27NO5S
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0401336
2-isobutoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C27H29NO5S
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0386120
2-(S)-2-(2-benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid
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C29H28N2O5
 1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CP0372812
(S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-4-yl)propanoic acid
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C25H25NO5S
 1
1
EC50 = 7 nM
   TI
   LI
   LO
   TS
CP0388725
(S)-2-ethoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C26H24F3NO5S
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0386098
(S)-2-(cyclopropylmethoxy)-3-(4-(2-(2-(4-isopropylphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C30H33NO5S
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0401332
(S)-3-(4-(2-(2-(4-isopropylphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-methoxypropanoic acid
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C27H29NO5S
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0386118
(S)-3-(4-(2-(2-(3,5-dimethylphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-methoxypropanoic acid
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C26H27NO5S
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0388063
3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-propoxypropanoic acid
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C26H27NO5S
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0386095
3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)naphthalen-1-yl)-2-propoxypropanoic acid
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C28H29NO5
 1
1
EC50 = 16 nM
   TI
   LI
   LO
   TS
CP0386096
2-ethoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C25H25NO5S
 1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0386099
(S)-2-ethoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)ethoxy)naphthalen-1-yl)propanoic acid
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C28H26F3NO5
 1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0401333
(S)-2-ethoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C25H25NO5S
 1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0401338
(2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid
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C24H23NO5S
 1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0493901
(S)-3-(4-(2-(2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-methoxypropanoic acid
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C26H27NO7S
 1
1
EC50 = 23 nM
   TI
   LI
   LO
   TS
CP0386100
(S)-2-(cyclopropylmethoxy)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C27H27NO5S
 1
1
EC50 = 32 nM
   TI
   LI
   LO
   TS
CP0372811
(S)-2-methoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-4-yl)propanoic acid
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C24H23NO5S
 1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
CP0468527
(S)-2-ethoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)naphthalen-1-yl)propanoic acid
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C27H27NO5
 1
1
EC50 = 37 nM
   TI
   LI
   LO
   TS
CP0401334
(S)-3-(4-(2-(2-(biphenyl-4-yl)-5-methyloxazol-4-yl)ethoxy)naphthalen-1-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid
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C33H28F3NO5
 1
1
EC50 = 38 nM
   TI
   LI
   LO
   TS
CP0372813
(S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C25H22F3NO5S
 1
1
EC50 = 53 nM
   TI
   LI
   LO
   TS
CP0401330
2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C24H23NO5S
 1
1
EC50 = 59 nM
   TI
   LI
   LO
   TS
CP0386101
(R)-2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)naphthalen-1-yl)propanoic acid
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C26H25NO5
 1
1
EC50 = 122 nM
   TI
   LI
   LO
   TS
CP0373163
2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)naphthalen-1-yl)propanoic acid
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C26H25NO5
 1
1
EC50 = 123 nM
   TI
   LI
   LO
   TS
CP0372814
(S)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid
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C25H22F3NO5S
 1
1
EC50 = 151 nM
   TI
   LI
   LO
   TS
CP0372815
(S)-3-(4-(2-(2-(biphenyl-4-yl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)-2-ethoxypropanoic acid
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C31H29NO5S
 1
1
EC50 = 431 nM
   TI
   LI
   LO
   TS
CP0005387
Avandamet
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C18H19N3O3S
 1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
CP0386097
2-methoxy-3-(4-(2-(5-methyl-2-o-tolyloxazol-4-yl)ethoxy)naphthalen-1-yl)propanoic acid
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C27H27NO5
 1
1
EC50 = 716 nM
   TI
   LI
   LO
   TS
CP0401335
(R)-2-ethoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C25H25NO5S
 1
1
EC50 = 787 nM
   TI
   LI
   LO
   TS
CP0388065
(R)-2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C24H23NO5S
 1
1
EC50 = 1210 nM
   TI
   LI
   LO
   TS
CP0386117
2-methoxy-3-(4-(2-(2-(2-methoxyphenyl)-5-methyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
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C25H25NO6S
 1
1
EC50 = 1615 nM
   TI
   LI
   LO
   TS