Brief Information of the Cell Line and Protein
Cell Line ID: CL000050 , HEK293-A
Synonyms
HEK-293A
HEK293A
HEK 293A
293A
QBI-HEK 293A
QBI-293A
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6910
Protein ID: PT06978 , Anoctamin-1
Gene Name ANO1
Organism Mus musculus, Mouse
Protein Classification Ion channel
Uniprot ID Q8BHY3
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000050  Protein ID: PT06978
 
Compound ID Compound Name Compound Formula
CP0427069
2-(4-chloro-2-methylphenoxy)-N-[(E)-(2-methoxyphenyl)methylideneamino]acetamide
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C17H17ClN2O3
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0469978
2-[(2-bromo-2,2-difluoroacetyl)amino]-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide
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C19H19BrF2N2O2S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0472409
6-tert-butyl-2-(furan-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
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C18H21NO4S
 1
1
IC50 = 1530 nM
   TI
   LI
   LO
   TS
CP0443972
2-[(4-chlorobenzoyl)carbamothioylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
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C16H14ClN3O2S2
 1
1
IC50 = 1750 nM
   TI
   LI
   LO
   TS
CP0244281
2-amino-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
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C13H20N2OS
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0424565
6-tert-butyl-2-(2,2-dimethylpropanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
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C18H28N2O2S
 1
1
IC50 = 2560 nM
   TI
   LI
   LO
   TS
CP0553275
2-(benzoylcarbamothioylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
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C16H15N3O2S2
 1
1
IC50 = 2630 nM
   TI
   LI
   LO
   TS
CP0507436
2-[(5-ethyl-4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-[5-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
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C19H20N4O3S2
 1
1
IC50 = 2740 nM
   TI
   LI
   LO
   TS
CP0546090
2-[(2-chlorobenzoyl)carbamothioylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
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C16H14ClN3O2S2
 1
1
IC50 = 3120 nM
   TI
   LI
   LO
   TS
CP0424564
2-(2,2-dimethylpropanoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide
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C15H22N2O2S
 1
1
IC50 = 4070 nM
   TI
   LI
   LO
   TS
CP0560539
2-(benzoylcarbamothioylamino)-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
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C21H25N3O2S2
 1
1
IC50 = 5660 nM
   TI
   LI
   LO
   TS