| Compound ID |
Compound Name |
Compound Formula |
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CP0955835
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(S)-4-((4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-4-((S)-1-amino-3-methyl-1-oxobutan-2-ylcarbamoyl)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-ylamino)-3-amino-4-oxobutanoic acid
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C50H65N11O11S2
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2
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| 1 |
EC50 = 0.45 nM
|
|
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| 2 |
IC50 = 0.9 nM
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CP0882707
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(4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-19-amino-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
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C46H60N10O8S2
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1
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| 1 |
EC50 = 0.83 nM
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CP0871322
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(S)-5-((2S,3R)-1-((S)-2-((S)-1-((4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-4-((S)-1-amino-3-methyl-1-oxobutan-2-ylcarbamoyl)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-ylamino)-3-carboxy-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-3-hydroxy-1-oxobutan-2-ylamino)-4-amino-5-oxopentanoic acid
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C64H86N14O17S2
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2
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| 1 |
EC50 = 1.46 nM
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| 2 |
IC50 = 2 nM
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CP0963262
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(S)-N1-((4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-4-((S)-1-amino-3-methyl-1-oxobutan-2-ylcarbamoyl)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)-2-aminopentanediamide
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C51H68N12O10S2
|
1
|
| 1 |
EC50 = 1.99 nM
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CP0958370
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(2S)-N1-((2S,5S,8S,11S)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-11-(4-hydroxy-3-nitrobenzyl)-1-(1H-indol-3-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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C45H56N12O10
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2
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| 1 |
EC50 = 3.47 nM
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|
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| 2 |
IC50 = 1090 nM
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CP0944638
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(4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-19-amino-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
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C41H51N9O7S2
|
1
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| 1 |
EC50 = 3.8 nM
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|
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CP0882706
|
(4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-19-((2S,3R)-2-amino-3-hydroxybutanamido)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
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C50H67N11O10S2
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1
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| 1 |
EC50 = 3.9 nM
|
|
|
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CP0946524
|
Urolinin
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C45H56N12O10
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2
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| 1 |
EC50 = 4.75 nM
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| 2 |
IC50 = 600 nM
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CP0946118
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(4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)-19-((S)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
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|
C55H69N11O9S2
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
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CP0943562
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(S)-N1-((2R,5S,8S,11S,14S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-5-(4-hydroxy-3-nitrobenzyl)-2-(mercaptomethyl)-15-(naphthalen-2-yl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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|
C46H55N11O10S
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2
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| 1 |
EC50 = 8.13 nM
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| 2 |
IC50 = 430 nM
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CP0882704
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(S)-N1-((3S,6R,9S,12S,15S,18S,21S)-15-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-18-benzyl-3-carbamoyl-9-(4-hydroxybenzyl)-6-(mercaptomethyl)-2,22-dimethyl-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatricosan-21-yl)-2-aminopentanediamide
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C53H74N12O10S
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1
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| 1 |
EC50 = 9.63 nM
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CP0954309
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(S)-N1-((2R,5S,8S,11S,14S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-5-(4-hydroxybenzyl)-15-(1H-indol-3-yl)-2-(mercaptomethyl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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C44H55N11O8S
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2
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| 1 |
EC50 = 10.01 nM
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|
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| 2 |
IC50 = 1550 nM
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CP0955097
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(S)-N1-((2R,5S,8S,11S,14S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-15-(1H-indol-3-yl)-2-(mercaptomethyl)-5-(4-methoxybenzyl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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|
C45H57N11O8S
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2
|
| 1 |
EC50 = 10.2 nM
|
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| 2 |
IC50 = 890 nM
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CP0871324
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(S)-6-amino-2-((S)-2-((S)-2-((S)-2-((2S,3R)-2-amino-3-hydroxybutanamido)-3-methylbutanamido)-3-phenylpropanamido)-3-(1H-indol-3-yl)propanamido)-N-((S)-1-((R)-1-((S)-1-amino-3-methyl-1-oxobutan-2-ylamino)-3-mercapto-1-oxopropan-2-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)hexanamide
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|
C52H73N11O10S
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1
|
| 1 |
EC50 = 11.2 nM
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|
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CP0943563
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(S)-N1-((2R,5S,8S,11S,14S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-5-(4-hydroxy-3-nitrobenzyl)-15-(1H-indol-3-yl)-2-(mercaptomethyl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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|
C44H54N12O10S
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2
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| 1 |
EC50 = 15.7 nM
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| 2 |
IC50 = 163 nM
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CP0882708
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(2R)-N1-((2S,5S,8S,11S)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-11-(4-hydroxybenzyl)-1-(1H-indol-3-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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|
C45H57N11O8
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2
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| 1 |
EC50 = 23 nM
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| 2 |
IC50 = 4830 nM
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CP0882709
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(2R)-N1-((2S,5S,8S,11S)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-11-(4-hydroxybenzyl)-1-(naphthalen-2-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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|
C47H58N10O8
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2
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| 1 |
EC50 = 25.5 nM
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| 2 |
IC50 = 4890 nM
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CP0960372
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(3S,6R,9S,12S,15S,18S,21S,24S)-21-((1H-imidazol-5-yl)methyl)-15-((1H-indol-3-yl)methyl)-24-amino-12-(4-aminobutyl)-18-benzyl-3-carbamoyl-9-(4-hydroxybenzyl)-6-(mercaptomethyl)-2-methyl-5,8,11,14,17,20,23-heptaoxo-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid
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|
C53H69N13O11S
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1
|
| 1 |
EC50 = 29.8 nM
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CP0882710
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(3S,6R,9S,12S,15S,18S,21S,24S)-15-((1H-indol-3-yl)methyl)-24-amino-12-(4-aminobutyl)-18-benzyl-3-carbamoyl-9-(4-hydroxybenzyl)-21-isopropyl-6-(mercaptomethyl)-2-methyl-5,8,11,14,17,20,23-heptaoxo-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid
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|
C52H71N11O11S
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2
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| 1 |
EC50 = 32.6 nM
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| 2 |
IC50 = 300 nM
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CP0882705
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(3S,6S,9S,12S,15S,18S)-12,15-bis((1H-indol-3-yl)methyl)-18,20-diamino-9-(4-aminobutyl)-3-carbamoyl-6-(4-hydroxybenzyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16-pentaazaicosan-1-oic acid
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|
C45H55N11O10
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1
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| 1 |
EC50 = 50.4 nM
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CP0882711
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(2S)-N1-((2S,5S,8S,11S)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-11-(4-hydroxybenzyl)-1-(1H-indol-3-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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|
C45H57N11O8
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2
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| 1 |
EC50 = 60 nM
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| 2 |
IC50 > 10000 nM
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CP0958002
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(4S,7S,10S,13S,16S,19S)-13,16-bis((1H-indol-3-yl)methyl)-19,21-diamino-10-(4-aminobutyl)-4-carbamoyl-7-(4-hydroxybenzyl)-6,9,12,15,18,21-hexaoxo-5,8,11,14,17-pentaazahenicosan-1-oic acid
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|
C46H57N11O10
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1
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| 1 |
EC50 = 65.6 nM
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CP0882713
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(2S)-N1-((2R,5S,8S,11S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-5-(4-hydroxybenzyl)-2-(mercaptomethyl)-15-(naphthalen-2-yl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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|
C46H56N10O8S
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2
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| 1 |
EC50 = 74.9 nM
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| 2 |
IC50 = 3056 nM
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CP0946114
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(S)-N1-((2S,5S,8S,11S,14S)-11-((1H-indol-3-yl)methyl)-1-amino-8-(4-aminobutyl)-5-(4-hydroxybenzyl)-2-(hydroxymethyl)-15-(1H-indol-3-yl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazapentadecan-14-yl)-2-aminosuccinamide
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|
C44H55N11O9
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1
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| 1 |
EC50 = 91.5 nM
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CP0954308
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(S)-6-amino-2-((S)-2-((S)-2-((2S,3R)-2-amino-3-hydroxybutanamido)-3-(1H-indol-3-yl)propanamido)-3-(1H-indol-3-yl)propanamido)-N-((S)-1-((R)-1-amino-3-mercapto-1-oxopropan-2-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)hexanamide
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C44H56N10O8S
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1
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| 1 |
EC50 = 103 nM
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CP0958371
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(2S)-N1-((5S,8S,11S)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-11-(4-hydroxybenzyl)-1-(naphthalen-2-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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|
C47H58N10O8
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2
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| 1 |
EC50 = 107.9 nM
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| 2 |
IC50 = 7880 nM
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CP0958369
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(S)-6-amino-N-((S)-1-((R)-1-amino-3-mercapto-1-oxopropan-2-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-2-((S)-2-((S)-2-amino-3-phenylpropanamido)-3-(1H-indol-3-yl)propanamido)hexanamide
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|
C38H48N8O6S
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1
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| 1 |
EC50 = 141 nM
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CP0957897
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(S)-N1-((2S,5S,8S,11S,14S,15R)-5-((1H-indol-3-yl)methyl)-8-(4-aminobutyl)-14-carbamoyl-15-hydroxy-11-(4-hydroxybenzyl)-1-(1H-indol-3-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazahexadecan-2-yl)-2-aminosuccinamide
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|
C45H57N11O9
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1
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| 1 |
EC50 = 143 nM
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CP0944877
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(3S,6R,9S,12S,15S,18S,21S,24S)-15-((1H-indol-3-yl)methyl)-24-amino-21-(2-amino-2-oxoethyl)-12-(4-aminobutyl)-18-benzyl-3-carbamoyl-9-(4-hydroxybenzyl)-6-(mercaptomethyl)-2-methyl-5,8,11,14,17,20,23-heptaoxo-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid
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|
C51H68N12O12S
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1
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| 1 |
EC50 = 155.5 nM
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CP0882703
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(S)-6-amino-N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-2-((S)-2-((S)-2-amino-3-phenylpropanamido)-3-(1H-indol-3-yl)propanamido)hexanamide
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|
C35H43N7O5
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1
|
| 1 |
EC50 = 179 nM
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CP0946115
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(S)-6-amino-N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-2-((S)-2-((S)-2-((R)-2-amino-3-mercaptopropanamido)-3-phenylpropanamido)-3-(1H-indol-3-yl)propanamido)hexanamide
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|
C38H48N8O6S
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1
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| 1 |
EC50 = 201 nM
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CP0882712
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5-((2S,5S,8S,11S,14S)-8,11-bis((1H-indol-3-yl)methyl)-14,16-diamino-2-((R)-1-amino-3-mercapto-1-oxopropan-2-ylcarbamoyl)-5-(4-aminobutyl)-4,7,10,13,16-pentaoxo-3,6,9,12-tetraazahexadecyl)-2-hydroxybenzenesulfonic acid
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C44H55N11O11S2
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2
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| 1 |
EC50 = 330 nM
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| 2 |
IC50 > 10000 nM
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CP0944639
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(S)-6-amino-2-((S)-2-((S)-2-amino-3-phenylpropanamido)-3-(1H-indol-3-yl)propanamido)hexanamide
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C26H34N6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0944640
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(S)-6-amino-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)hexanamide
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C26H34N6O4
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1
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| 1 |
EC50 > 10000 nM
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