| Compound ID |
Compound Name |
Compound Formula |
|
CP0073616
|
1-[3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-4-methyl-5-(2-pyrrolidin-1-ylethylamino)phenyl]propan-1-one
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|
C25H33BrN8O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0322941
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-2-methyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-pyrrolidin-1-ylethyl)aniline
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|
C25H31BrN10O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0247186
|
methyl 3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-4-methyl-5-(2-pyrrolidin-1-ylethylamino)benzoate
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|
C24H31BrN8O2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0315540
|
1-[3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-4-methyl-5-(2-pyrrolidin-1-ylethylamino)phenyl]-4,4,4-trifluorobutan-1-one
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|
C26H32BrF3N8O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0146240
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-2-methyl-N-(2-pyrrolidin-1-ylethyl)-5-(2,2,2-trifluoroethoxymethyl)aniline
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|
C25H32BrF3N8O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0248530
|
N-[3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-chloro-2-methylphenyl]-N',N'-dimethylethane-1,2-diamine
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|
C20H26BrClN8
|
1
|
| 1 |
IC50 = 141 nM
|
|
|
|
CP0146238
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-4-methyl-N-phenyl-5-(2-pyrrolidin-1-ylethylamino)benzamide
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|
C29H34BrN9O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0237101
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-(3,3-dimethylbutyl)-2-methyl-N-(2-pyrrolidin-1-ylethyl)aniline
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|
C28H41BrN8
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0125121
|
N-[5-chloro-3-[4-(3-ethyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-2-methylphenyl]-N',N'-dimethylethane-1,2-diamine
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|
C22H31ClN8
|
1
|
| 1 |
IC50 = 211 nM
|
|
|
|
CP0192555
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-2-methyl-5-(2-methylpropoxy)-N-(2-pyrrolidin-1-ylethyl)aniline
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|
C26H37BrN8O
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0151040
|
3-[4-(3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-5-chloro-2-methyl-N-(2-pyrrolidin-1-ylethyl)aniline
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|
C22H28BrClN8
|
1
|
| 1 |
IC50 = 446 nM
|
|
|
|
CP0272288
|
5-chloro-3-[4-(3-ethyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl]-2-methyl-N-(2-pyrrolidin-1-ylethyl)aniline
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|
C24H33ClN8
|
1
|
| 1 |
IC50 = 832 nM
|
|
|
