Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
 Cell Line Info 
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT05058 , Interleukin-1 beta
 Protein Info 
Gene Name IL1B
Organism Homo sapiens, Human
Protein Classification Secreted protein
Uniprot ID P01584
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040
 Cell Line Info 
 Protein ID: PT05058
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0270369
 Compound Info 
(3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanamido]-3-methylbutanamido]propanamido]-4-oxobutanoic acid
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C23H32N4O8
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463261
 Compound Info 
methyl (1R,2S,5S,7R,10S,11S,13R,15S)-7,15-dihydroxy-2,6,6,10,13,15-hexamethyl-17-methylidene-14,16-dioxotetracyclo[11.3.1.02,11.05,10]heptadecane-1-carboxylate
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C26H38O6
  1
1
IC50 = 2700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463262
 Compound Info 
methyl (1R,2S,11S,12S,14R,16S)-16-hydroxy-2,6,6,11,14,16-hexamethyl-18-methylidene-8,15,17-trioxo-7-oxatetracyclo[12.3.1.02,12.05,11]octadec-4-ene-1-carboxylate
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C26H34O7
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0287901
 Compound Info 
BERKELEYDIONE
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C26H32O7
  1
1
IC50 = 4400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392419
 Compound Info 
methyl (1R,2S,5S,10S,11S,13R,15S)-15-hydroxy-2,6,6,10,13,15-hexamethyl-17-methylidene-7,14,16-trioxotetracyclo[11.3.1.02,11.05,10]heptadecane-1-carboxylate
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C26H36O6
  1
1
IC50 = 15500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451942
 Compound Info 
methyl (1R,2S,5R,11S,12S,14R,16S)-16-hydroxy-2,6,6,11,14,16-hexamethyl-18-methylidene-8,15,17-trioxo-7-oxatetracyclo[12.3.1.02,12.05,11]octadecane-1-carboxylate
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C26H36O7
  1
1
IC50 = 34300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475463
 Compound Info 
3-[(1R,2S,6S,7S,9R,11S)-11-hydroxy-1-methoxycarbonyl-2,6,9,11-tetramethyl-13-methylidene-10,12-dioxo-5-prop-1-en-2-yl-6-tricyclo[7.3.1.02,7]tridec-4-enyl]propanoic acid
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C26H34O7
  1
1
IC50 = 37800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS