Brief Information of the Cell Line and Protein
Cell Line ID: CL000035 , NIH 3T3
 Cell Line Info 
Synonyms
NIH/3T3
NIH-3T3
NIH3T3
3T3
3T3NIH
3T3-Swiss
Swiss-3T3
Swiss/3T3
Swiss 3T3
Swiss3T3
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0594
Protein ID: PT06138 , Glycogen synthase kinase-3 beta
 Protein Info 
Gene Name GSK3B
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID Q9WV60
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000035
 Cell Line Info 
 Protein ID: PT06138
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0011176
 Compound Info 
3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonyl-2-(trifluoromethyl)phenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C22H22F3N7O3S
  1
1
IC50 = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012712
 Compound Info 
3-amino-6-(4-morpholin-4-ylsulfonylphenyl)-N-pyridin-3-ylpyrazine-2-carboxamide
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C20H20N6O4S
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0013596
 Compound Info 
3-amino-6-[2-methyl-4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C22H25N7O3S
  1
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012711
 Compound Info 
3-amino-6-[4-[2-(dimethylamino)ethylsulfamoyl]phenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C20H23N7O3S
  1
1
IC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012710
 Compound Info 
3-amino-6-[4-[2-(dimethylamino)ethyl-ethylsulfamoyl]phenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C22H27N7O3S
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0009422
 Compound Info 
3-amino-6-[3-fluoro-4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C21H22FN7O3S
  1
1
IC50 = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0008569
 Compound Info 
3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
   Show/Hide
C21H23N7O3S
  1
1
IC50 = 76 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0009420
 Compound Info 
3-amino-6-[4-(2-methoxyethylsulfamoyl)phenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
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C19H20N6O4S
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0009999
 Compound Info 
3-amino-6-(4-piperidin-1-ylsulfonylphenyl)-N-pyridin-3-ylpyrazine-2-carboxamide
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C21H22N6O3S
  1
1
IC50 = 87 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS