All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000035 , NIH 3T3

Cell Line Info

Synonyms	NIH/3T3 NIH-3T3 NIH3T3 3T3 3T3NIH 3T3-Swiss Swiss-3T3 Swiss/3T3 Swiss 3T3 Swiss3T3
Category	Spontaneously immortalized cell line
Organism	Mus musculus (Mouse)
Cellosaurus ID	CVCL_0594

Protein ID: PT06127 , Gastrin-releasing peptide receptor

Protein Info

Gene Name	GRPR
Organism	Mus musculus, Mouse
Protein Classification	Membrane receptor
Uniprot ID	P21729

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000035

Cell Line Info

Protein ID: PT06127

Protein Info

Compound ID	Compound Name	Compound Formula
CP0409836 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-phenylcyclopropane-1-carboxamide Show/Hide	C58H72N14O8	2
1	IC50 = 0.03 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.049 nM Bioactivity Info	TI LI LO TS
CP0441769 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H72N14O8	1
1	IC50 = 0.038 nM Bioactivity Info	TI LI LO TS
CP0451514 Compound Info	1-naphthyl(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C59H70N14O8	1
1	IC50 = 0.05 nM Bioactivity Info	TI LI LO TS
CP0448646 Compound Info	4-OHPhCH2CH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C57H72N14O9	2
1	IC50 = 0.05 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.23 nM Bioactivity Info	TI LI LO TS
CP0459367 Compound Info	2-tetrahydronaphthyl(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C59H74N14O8	2
1	IC50 = 0.079 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.3 nM Bioactivity Info	TI LI LO TS
CP0377335 Compound Info	(2S)-N-[2-[[(2S)-1-[(2S)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-N,3-dimethylbutanamide Show/Hide	C57H72N14O8	2
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0451264 Compound Info	2-aminoPhCH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C56H71N15O8	2
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0459359 Compound Info	N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]propanoyl]amino]-6-methylheptanamide Show/Hide	C60H78N14O10	2
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.3 nM Bioactivity Info	TI LI LO TS
CP0406764 Compound Info	3-CF3PhCH2CH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C58H71F3N14O8	2
1	IC50 = 0.16 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0432964 Compound Info	(CH3)2PhC(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C58H74N14O8	1
1	IC50 = 0.18 nM Bioactivity Info	TI LI LO TS
CP0395492 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(3S)-3-phenylbutanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C58H74N14O8	2
1	IC50 = 0.21 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0377334 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H72N14O8	1
1	IC50 = 0.22 nM Bioactivity Info	TI LI LO TS
CP0409762 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H72N14O9	1
1	IC50 = 0.33 nM Bioactivity Info	TI LI LO TS
CP0448849 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(3R)-3-phenylbutanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C58H74N14O8	1
1	IC50 = 0.49 nM Bioactivity Info	TI LI LO TS
CP0482730 Compound Info	3-isoquinolyl(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C58H69N15O8	1
1	IC50 = 0.57 nM Bioactivity Info	TI LI LO TS
CP0527749 Compound Info	2-{2-[2-[2-(2,2-Dimethyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-hexylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C48H72N12O7	2
1	IC50 = 0.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0514967 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-3-(1-benzothiophen-3-yl)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H71N13O8S	1
1	IC50 = 0.75 nM Bioactivity Info	TI LI LO TS
CP0406766 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2R)-2-phenylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H72N14O8	2
1	IC50 = 0.95 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0409649 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-2-(3-phenylpropanoylamino)-3-thiophen-2-ylpropanoyl]amino]propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C58H72N12O8S	2
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.6 nM Bioactivity Info	TI LI LO TS
CP0461143 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-phenylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C57H72N14O8	2
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0375748 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O7	2
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0463151 Compound Info	(CH3)2PhCCH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C59H76N14O8	2
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0414805 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-pentylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O7	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0505280 Compound Info	Ac-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 Show/Hide	C46H66N14O9S	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0440473 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenothiazin-10-ylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C63H75N15O8S	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0509126 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-hexylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C45H66N12O7	2
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0407203 Compound Info	(2S)-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C61H74N14O8	2
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0400004 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-pentylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O7	2
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0404545 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(3-methyl-1-propyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C43H62N12O7	2
1	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0384171 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-heptylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C46H68N12O7	2
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0406141 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(3-methyl-1-propoxymethyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O8	2
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0504857 Compound Info	Ac-His-Trp-Ala-Val-D-Ala-His-Leu-Met-NH2 Show/Hide	C47H68N14O9S	1
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
CP0399869 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[1-(1-butyl-pentylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O7	2
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0448036 Compound Info	4-CF3PhCH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C57H69F3N14O8	1
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
CP0447980 Compound Info	2-[2-[2-(2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyrylamino)-acetylamino]-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoic acid ethyl ester Show/Hide	C43H60N12O9	2
1	IC50 = 3.9 nM Bioactivity Info	TI LI LO TS
2	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0503457 Compound Info	(CH3)CCO-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 Show/Hide	C49H72N14O9S	1
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0380786 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(3-methyl-1-propyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C43H62N12O7	2
1	IC50 = 4.9 nM Bioactivity Info	TI LI LO TS
2	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0497940 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[1-(1-ethoxymethyl-3-methyl-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C44H64N12O8	2
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0449423 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{1-[1-(1-ethoxymethyl-3-methyl-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-ethyl}-3-methyl-butyramide Show/Hide	C43H62N12O8	2
1	IC50 = 6.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0453558 Compound Info	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[(2R)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamide Show/Hide	C61H75N15O8	1
1	IC50 = 7.7 nM Bioactivity Info	TI LI LO TS
CP0437445 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-methoxymethyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C42H60N12O8	2
1	IC50 = 8.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 91 nM Bioactivity Info	TI LI LO TS
CP0451570 Compound Info	3-CF3PhCH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C57H69F3N14O8	1
1	IC50 = 8.4 nM Bioactivity Info	TI LI LO TS
CP0406381 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-({2-(3H-imidazol-4-yl)-1-[3-methyl-1-(3-methyl-butoxymethyl)-butylcarbamoyl]-ethylcarbamoyl}-methyl)-3-methyl-butyramide Show/Hide	C46H68N12O8	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0437371 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-hexylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C45H66N12O7	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0453631 Compound Info	2-CF3PhCH2CH2(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2 Show/Hide	C57H69F3N14O8	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0430287 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-propyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C42H60N12O7	2
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
2	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0459222 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-hydroxy-3-oxopropyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C59H74N14O10	2
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
2	IC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0496398 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2R)-2-[3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-hydroxy-3-oxopropyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide Show/Hide	C59H74N14O10	2
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
2	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0448760 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[1-(1-hydroxymethyl-3-methyl-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide Show/Hide	C41H58N12O8	2
1	IC50 = 81 nM Bioactivity Info	TI LI LO TS
2	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0469362 Compound Info	Ac-His-Trp-Ala-Val-Ala-His-Leu-Met-NH2 Show/Hide	C47H68N14O9S	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0441706 Compound Info	2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{1-[1-(1-ethoxymethyl-3-methyl-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-ethyl}-3-methyl-butyramide Show/Hide	C44H64N12O8	2
1	IC50 = 410 nM Bioactivity Info	TI LI LO TS
2	IC50 > 300 nM Bioactivity Info	TI LI LO TS
CP0448848 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]methyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(3-phenylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propyl]amino]-3-methylbutanamide Show/Hide	C57H74N14O7	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS

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Prof. Feng ZHU

Prof. Leo, Lianyi Han