| Compound ID |
Compound Name |
Compound Formula |
|
CP0497929
|
(R)-3-Amino-4-(5-chloro-2-fluoro-phenyl)-N-{4-[6-(2-methoxy-ethoxy)-benzothiazol-2-yl]-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl}-butyramide
Show/Hide
|
C25H29ClFN3O5S2
|
1
|
| 1 |
IC50 = 0.64 nM
|
|
|
|
CP0453621
|
(R)-3-Amino-N-{4-[6-(2-morpholin-4-yl-ethoxy)-benzothiazol-2-yl]-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl}-4-(2,4,5-trifluoro-phenyl)-butyramide
Show/Hide
|
C28H33F3N4O5S2
|
1
|
| 1 |
IC50 = 0.79 nM
|
|
|
|
CP0079344
|
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C25H28N8O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0285875
|
(R)-2-(2-(2-(8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-2,6-dioxo-2,3-dihydro-6H-purin-1(7H)-yl)acetyl)phenoxy)-N-methylacetamide
Show/Hide
|
C26H31N7O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0202500
|
2-[(3R)-3-aminopiperidin-1-yl]-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C24H26N8O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0437322
|
2-(2-aminoethylamino)-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C21H22N8O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0458033
|
2-[(3R)-3-aminopiperidin-1-yl]-3-but-2-ynyl-7-methyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C25H28N8O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0511948
|
(R)-3-Amino-N-{4-[6-(2-methoxy-ethoxy)-benzothiazol-2-yl]-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl}-4-(2,4,5-trifluoro-phenyl)-butyramide
Show/Hide
|
C25H28F3N3O5S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0684514
|
1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-L-prolinamide dihydrochloride
Show/Hide
|
C25H36Cl2N4O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0920228
|
Methyl 1-{[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-L-prolinate dihydrochloride
Show/Hide
|
C26H37Cl2N3O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0666319
|
1-(3-(aminomethyl)-2-isobutyl-4-p-tolylquinolin-6-yl)piperazine-2,5-dione dihydrochloride
Show/Hide
|
C25H30Cl2N4O2
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 1.3 nM
|
|
|
|
CP0905285
|
3-({[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)benzamide dihydrochloride
Show/Hide
|
C28H35Cl2N3O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0512525
|
(E)-3-[3-(aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]prop-2-enamide
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0486586
|
(R)-3-amino-4-(5-chloro-2-fluorophenyl)-N-(4-(6-(2-methoxyethoxy)benzo[d]thiazol-2-yl)tetrahydro-2H-pyran-4-yl)butanamide
Show/Hide
|
C25H29ClFN3O4S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0159038
|
(S)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylmethyl)-3-methyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C26H31N7O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0513677
|
2-[[(2S)-2-aminopropyl]amino]-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C22H24N8O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0855625
|
8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((3-methylisoquinolin-1-yl)methyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0176061
|
N-[(2,4-difluorophenyl)methyl]-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H18F2N6
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0512558
|
4-[3-(aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]piperazin-2-one
Show/Hide
|
C25H30N4O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0756597
|
5-(Aminomethyl)-2-benzyl-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C26H32Cl2N2O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0421229
|
(R)-3-Amino-N-[4-(6-methoxy-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-4-(2,4,5-trifluoro-phenyl)-butyramide
Show/Hide
|
C23H24F3N3O4S2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0534620
|
1-[3-(aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]piperazine-2,3-dione
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0941699
|
2-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]-N-[3-(methylsulfinyl)phenyl]acetamidedi hydrochloride
Show/Hide
|
C27H34ClN3O2S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0929412
|
1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-L-proline dihydrochloride
Show/Hide
|
C25H35Cl2N3O3
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0053807
|
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((3-methylisoquinolin-1-yl)methyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0059084
|
8-((S)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0437324
|
2-[(3R)-3-aminopiperidin-1-yl]-5-(benzo[b][1,4]benzoxazepin-6-ylmethyl)-3-but-2-ynylimidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C28H27N7O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0513680
|
3-but-2-ynyl-2-(1,4-diazepan-1-yl)-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C24H26N8O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0529982
|
(R)-3-Amino-N-[4-(5-methoxy-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-4-(2,4,5-trifluoro-phenyl)-butyramide
Show/Hide
|
C23H24F3N3O4S2
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0399076
|
(3R)-3-amino-4-(2,4,5-trifluorophenyl)-N-{4-[6-(2-methoxyethoxy)benzothiazol-2-yl]tetrahydropyran-4-yl}butanamide
Show/Hide
|
C25H28F3N3O4S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0949668
|
Methyl3-({[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)benzoate dihydrochloride
Show/Hide
|
C28H35Cl2N3O3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0192149
|
(R)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylmethyl)-3-methyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C26H31N7O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0435251
|
8-((R)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0437329
|
4-[[2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-4-oxoimidazo[4,5-d]pyridazin-5-yl]methyl]naphthalene-1-carbonitrile
Show/Hide
|
C26H25N7O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0511517
|
2-(3-aminopiperidin-1-yl)-5-(1,3-benzoxazol-2-ylmethyl)-3-but-2-ynylimidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C22H23N7O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0053608
|
2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile
Show/Hide
|
C18H21N5O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0498813
|
2-[3-(aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]oxyacetamide
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0803636
|
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)-2-propylpyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C22H32Cl2N2O2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0844246
|
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)-2-(2-methylpropyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0052765
|
8-(3-Amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0437323
|
3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]-2-piperazin-1-ylimidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C23H24N8O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0486571
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-[(3-methylisoquinolin-1-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C25H27N7O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0911852
|
[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridin-3-yl]acetic acid hydrate
Show/Hide
|
C22H32N2O3
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0767770
|
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C21H30Cl2N2O2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0075223
|
8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0923353
|
6-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)-quinolin-6-yl]hexanoic Acid Dihydrochloride
Show/Hide
|
C27H36Cl2N2O2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0513679
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-7-methyl-5-[(3-methylisoquinolin-1-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C26H29N7O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0920902
|
3-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]propanamide dihydrochloride
Show/Hide
|
C24H31Cl2N3O
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0873155
|
1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-D-proline dihydrochloride
Show/Hide
|
C25H35Cl2N3O3
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0187017
|
(R)-1-(4-methoxybenzyl)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0900431
|
N-(3-Acetylphenyl)-2-[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetamide dihydrochloride
Show/Hide
|
C27H34Cl2N4O2
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0901948
|
2-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]-N-[3-(methylsulfonyl)phenyl]acetamide dihydrochloride
Show/Hide
|
C27H35Cl2N3O3S
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0944167
|
4-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)-quinolin-6-yl]butanoic acid Dihydrochloride
Show/Hide
|
C25H32Cl2N2O2
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0427980
|
8-((S)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0941520
|
1-[4-(4-Methylphenyl)-2-(2-methylpropyl)-6-(2H-tetrazol-5-yl)quinolin-3-yl]methanamine dihydrochloride
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0929925
|
5-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)-quinolin-6-yl]pentanoic Acid Dihydrochloride
Show/Hide
|
C26H34Cl2N2O2
|
1
|
| 1 |
IC50 = 9.6 nM
|
|
|
|
CP0752501
|
[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-methyl-4-(4-methylphenyl)pyridin-3-yl]acetic Acid Dihydrochloride
Show/Hide
|
C21H30Cl2N2O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0949669
|
Methyl 1-{[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}pyrrolidine-3-carboxylate dihydrochloride
Show/Hide
|
C26H37Cl2N3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0923211
|
3-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]-1,2,4-oxadiazol-5(4H)-one dihydrochloride
Show/Hide
|
C23H26Cl2N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0531941
|
(R)-3-Amino-4-(2-fluoro-phenyl)-N-[4-(6-methoxy-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-butyramide
Show/Hide
|
C23H26FN3O4S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0929413
|
1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-D-prolinamide dihydrochloride
Show/Hide
|
C25H36Cl2N4O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0486572
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-(naphthalen-1-ylmethyl)imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C25H26N6O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0511414
|
(R)-3-Amino-N-(4-benzothiazol-2-yl-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2,4,5-trifluoro-phenyl)-butyramide
Show/Hide
|
C22H22F3N3O3S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0893472
|
2-(3-Amino-piperidin-1-yl)-3-but-2-ynyl-5-dibenzo[b,f][1,4]oxazepin-11-ylmethyl-3,5-dihydro-imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C28H27N7O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0458035
|
8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(naphthalen-1-ylmethyl)purine-2,6-dione
Show/Hide
|
C26H28N6O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0920229
|
Methyl N-{[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}glycinate dihydrochloride
Show/Hide
|
C23H33Cl2N3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0518446
|
5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridine-3-carboxic acid
Show/Hide
|
C19H24N2O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0721302
|
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-methyl-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C20H28Cl2N2O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0772190
|
5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
|
C19H26Cl2N2O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0437327
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-7-methoxy-5-[(3-methylisoquinolin-1-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0847852
|
Methyl2-({[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)benzoate dihydrochloride
Show/Hide
|
C28H35Cl2N3O3
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1
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| 1 |
IC50 = 19 nM
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CP0954916
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3-({[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)benzoic acid dihydrochloride
Show/Hide
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C27H33Cl2N3O3
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1
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| 1 |
IC50 = 19 nM
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CP0785521
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5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-(1-methylethyl)-4-(4-methylphenyl)pyridine-3-carboxylic acid Dihydrochloride
Show/Hide
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C22H32Cl2N2O2
|
1
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| 1 |
IC50 = 19 nM
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CP0844245
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[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetic Acid Dihydrochloride
Show/Hide
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C20H28Cl2N2O2
|
1
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| 1 |
IC50 = 20 nM
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CP0445938
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2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-[(3-methylisoquinolin-1-yl)methyl]imidazo[4,5-c]pyridin-4-one
Show/Hide
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C26H28N6O
|
1
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| 1 |
IC50 = 21 nM
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CP0899529
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Methyl 4-({[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)thiophene-3-carboxylate dihydrochloride
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C26H33Cl2N3O3S
|
1
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| 1 |
IC50 = 23 nM
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CP0954917
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Methyl 1-{[5-(aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-D-prolinate dihydrochloride
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C26H37Cl2N3O3
|
1
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| 1 |
IC50 = 23 nM
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CP0917776
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3-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)-quinolin-6-yl]propanoic Acid Dihydrochloride
Show/Hide
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C24H30Cl2N2O2
|
1
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| 1 |
IC50 = 23 nM
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CP0551866
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5-(3-aminopiperidin-1-yl)-4-but-2-ynyl-N-[(3-methylisoquinolin-1-yl)methyl]-1,2,4-triazole-3-carboxamide
Show/Hide
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C23H27N7O
|
1
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| 1 |
IC50 = 24 nM
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CP0513678
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2-[(3S)-3-aminopiperidin-1-yl]-5-(benzo[b][1,4]benzoxazepin-6-ylmethyl)-3-but-2-ynylimidazo[4,5-d]pyridazin-4-one
Show/Hide
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C28H27N7O2
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1
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| 1 |
IC50 = 25 nM
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CP0458032
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2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-phenacylimidazo[4,5-d]pyridazin-4-one
Show/Hide
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C22H24N6O2
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1
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| 1 |
IC50 = 26 nM
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CP0528716
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2-[3-(aminomethyl)-4-(4-fluorophenyl)-2-(2-methylpropyl)quinolin-6-yl]oxyacetamide
Show/Hide
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C22H24FN3O2
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1
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| 1 |
IC50 = 26 nM
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CP0920227
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4-({[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}amino)thiophene-3-carboxylic acid dihydrochloride
Show/Hide
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C25H31Cl2N3O3S
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1
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| 1 |
IC50 = 30 nM
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CP0450889
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2-[3-(aminomethyl)-2-(2-methylpropyl)-4-phenylquinolin-6-yl]oxyacetamide
Show/Hide
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C22H25N3O2
|
1
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| 1 |
IC50 = 34 nM
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CP0399966
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8-(3-aminopiperidin-1-yl)-1,3-dimethyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C17H26N6O2
|
1
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| 1 |
IC50 = 35 nM
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CP0529983
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(R)-3-Amino-N-[4-(6-chloro-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C22H23ClFN3O3S2
|
1
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| 1 |
IC50 = 35 nM
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CP0767769
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3-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]propanoic Acid Dihydrochloride
Show/Hide
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C21H30Cl2N2O2
|
1
|
| 1 |
IC50 = 39 nM
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CP0754069
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2-(3-(aminomethyl)-2-isobutyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yloxy)acetamide hydrochloride
Show/Hide
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C22H26ClN3O3
|
2
|
| 1 |
IC50 = 47 nM
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| 2 |
IC50 = 240 nM
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CP0390092
|
2-[3-(aminomethyl)-4-(3-fluorophenyl)-2-(2-methylpropyl)quinolin-6-yl]oxyacetamide
Show/Hide
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C22H24FN3O2
|
1
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| 1 |
IC50 = 49 nM
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CP0437328
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2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-7-methoxy-5-(naphthalen-1-ylmethyl)imidazo[4,5-d]pyridazin-4-one
Show/Hide
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C26H28N6O2
|
1
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| 1 |
IC50 = 52 nM
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CP0917133
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2-{[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]oxy}-N-methylacetamide dihydrochloride
Show/Hide
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C24H31Cl2N3O2
|
1
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| 1 |
IC50 = 52 nM
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CP0919563
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1-[6-Methyl-4-(4-methylphenyl)-2-(2-methylpropyl)-5-{2-[3-(methylsulfonyl)pyrrolidin-1-yl]-2-oxoethyl}pyridin-3-yl]methanamine dihydrochloride
Show/Hide
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C25H37Cl2N3O3S
|
1
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| 1 |
IC50 = 53 nM
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CP0847179
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3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinoline-6-carboxamide dihydrochloride
Show/Hide
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C22H27Cl2N3O
|
1
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| 1 |
IC50 = 55 nM
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CP0490884
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8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-enyl)-1-phenethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C24H32N6O2
|
1
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| 1 |
IC50 = 56 nM
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CP0790291
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5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-propylpyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
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C18H24Cl2N2O2
|
1
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| 1 |
IC50 = 57 nM
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CP0377659
|
2-[3-(aminomethyl)-4-(3-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]oxyacetamide
Show/Hide
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C23H27N3O2
|
1
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| 1 |
IC50 = 57 nM
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CP0903822
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5-(Aminomethyl)-6-butyl-2-methyl-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
Show/Hide
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C19H26Cl2N2O2
|
1
|
| 1 |
IC50 = 58 nM
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CP0441613
|
(R)-3-Amino-N-(4-benzothiazol-2-yl-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C22H24FN3O3S2
|
1
|
| 1 |
IC50 = 64 nM
|
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CP0721301
|
(2E)-3-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]prop-2-enoic Acid Dihydrochloride
Show/Hide
|
C21H28Cl2N2O2
|
1
|
| 1 |
IC50 = 66 nM
|
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CP0941700
|
2-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]-N-methylacetamide dihydrochloride
Show/Hide
|
C21H31Cl2N3O
|
1
|
| 1 |
IC50 = 69 nM
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CP0531942
|
(R)-3-Amino-4-(2-fluoro-phenyl)-N-[4-(6-methyl-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-butyramide
Show/Hide
|
C23H26FN3O3S2
|
1
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| 1 |
IC50 = 70 nM
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CP0919564
|
N-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}glycine dihydrochloride
Show/Hide
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C22H31Cl2N3O3
|
1
|
| 1 |
IC50 = 73 nM
|
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CP0239964
|
8-(3-aminopiperidin-1-yl)-7-benzyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C19H24N6O2
|
1
|
| 1 |
IC50 = 82 nM
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CP0935712
|
Methyl{[3-(aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]oxy}acetate dihydrochloride
Show/Hide
|
C24H30Cl2N2O3
|
1
|
| 1 |
IC50 = 84 nM
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CP0445426
|
8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C16H22N6O2
|
1
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| 1 |
IC50 = 88 nM
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CP0535426
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-(naphthalen-1-ylmethyl)imidazo[4,5-c]pyridin-4-one
Show/Hide
|
C26H27N5O
|
1
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| 1 |
IC50 = 89 nM
|
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CP0560532
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N-[2-(2,4-dichlorophenyl)ethyl]-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C18H20Cl2N6
|
1
|
| 1 |
IC50 = 89 nM
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CP0535425
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2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-N-[(3-methylisoquinolin-1-yl)methyl]imidazole-4-carboxamide
Show/Hide
|
C24H28N6O
|
1
|
| 1 |
IC50 = 99 nM
|
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CP0917409
|
3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinoline-6-carboxylic acid dihydrochloride
Show/Hide
|
C22H26Cl2N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
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CP0458034
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-N-(naphthalen-1-ylmethyl)imidazole-4-carboxamide
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 107 nM
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CP0007316
|
(1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorobenzyl)propylamine
Show/Hide
|
C16H15F6N5O
|
1
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| 1 |
IC50 = 110 nM
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CP0436127
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(R)-3-Amino-N-[4-(4-chloro-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C22H23ClFN3O3S2
|
1
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| 1 |
IC50 = 130 nM
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CP0284910
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(R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C18H22FN3O3S2
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1
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| 1 |
IC50 = 190 nM
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CP0500875
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7-(but-2-ynyl)-1,3-dimethyl-8-(piperazin-1-yl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C15H20N6O2
|
1
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| 1 |
IC50 = 200 nM
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CP0446016
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(R)-3-Amino-4-(2-fluoro-phenyl)-N-[4-(4-methoxy-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-butyramide
Show/Hide
|
C23H26FN3O4S2
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1
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| 1 |
IC50 = 270 nM
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CP0824113
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(2E)-3-[3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yl]prop-2-enamide hydrochloride
Show/Hide
|
C23H26ClN3O2
|
1
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| 1 |
IC50 = 280 nM
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CP0465496
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8-(3-aminopiperidin-1-yl)-1-benzyl-3-methyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C23H30N6O2
|
1
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| 1 |
IC50 = 284 nM
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CP0421383
|
5-[(3R)-3-aminopiperidin-1-yl]-N-benzylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C18H22N6
|
1
|
| 1 |
IC50 = 300 nM
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CP0916764
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1-Aminomethyl-6,8-dimethoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C15H19ClN2O4
|
1
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| 1 |
IC50 = 320 nM
|
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CP0460059
|
(R)-3-Amino-4-(2-fluoro-phenyl)-N-[4-(4-methyl-benzothiazol-2-yl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl]-butyramide
Show/Hide
|
C23H26FN3O3S2
|
1
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| 1 |
IC50 = 350 nM
|
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CP0734886
|
3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-6-carboxamide hydrochloride
Show/Hide
|
C21H24ClN3O2
|
1
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| 1 |
IC50 = 360 nM
|
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CP0555566
|
N-(2,4-difluorophenyl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H16F2N6
|
1
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| 1 |
IC50 = 400 nM
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CP0423705
|
(R)-3-Amino-N-(1,1-dioxo-4-pyridin-2-yl-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C20H24FN3O3S
|
1
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| 1 |
IC50 = 470 nM
|
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CP0546085
|
N-(2,4-dichlorophenyl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H16Cl2N6
|
1
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| 1 |
IC50 = 470 nM
|
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CP0727365
|
R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid HCl
Show/Hide
|
C22H22ClF3N4O5
|
1
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| 1 |
IC50 = 510 nM
|
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CP0437326
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2-(3-aminopiperidin-1-yl)-5-bromo-3-but-2-ynyl-N-(naphthalen-1-ylmethyl)imidazole-4-carboxamide
Show/Hide
|
C24H26BrN5O
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1
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| 1 |
IC50 = 559 nM
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CP0252609
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(R)-3-Amino-N-(1,1-dioxo-4-phenyl-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide
Show/Hide
|
C21H25FN2O3S
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1
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| 1 |
IC50 = 570 nM
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CP0305354
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1,3-dimethyl-7-(3-methylbut-2-enyl)-8-(piperazin-1-yl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C16H24N6O2
|
1
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| 1 |
IC50 = 580 nM
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CP0551867
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2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-5-cyano-N-(naphthalen-1-ylmethyl)imidazole-4-carboxamide
Show/Hide
|
C25H26N6O
|
1
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| 1 |
IC50 = 582 nM
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CP0939148
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(R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid ethyl ester HCl
Show/Hide
|
C24H26ClF3N4O5
|
1
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| 1 |
IC50 = 690 nM
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CP0858724
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(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid benzyl ester HCl
Show/Hide
|
C21H21ClF3N3O3
|
1
|
| 1 |
IC50 = 710 nM
|
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CP0876908
|
(R)-4-({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)benzoic acid ethyl ester HCl
Show/Hide
|
C23H24ClF3N4O4
|
1
|
| 1 |
IC50 = 770 nM
|
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CP0944843
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3-(Aminomethyl)-6-hydroxy-2-(2-methylpropyl)-4-phenylisoquinolin-1(2H)-one hydrochloride
Show/Hide
|
C20H23ClN2O2
|
1
|
| 1 |
IC50 = 790 nM
|
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CP0443978
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4-methyl-1-N-(5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-yl)benzene-1,2-diamine
Show/Hide
|
C17H21N7
|
1
|
| 1 |
IC50 = 800 nM
|
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CP0434565
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(R)-3-amino-4-(2-fluorophenyl)-N-(1-methyl-4-phenylpiperidin-4-yl)butanamide
Show/Hide
|
C22H28FN3O
|
1
|
| 1 |
IC50 = 870 nM
|
|
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CP0531040
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3-(aminomethyl)-6-methoxy-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
IC50 = 870 nM
|
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CP0915402
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3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-6-carboxylic acid hydrochloride
Show/Hide
|
C21H23ClN2O3
|
1
|
| 1 |
IC50 = 980 nM
|
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CP0423704
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(R)-3-amino-N-(1-benzyl-4-phenylpiperidin-4-yl)-4-(2-fluorophenyl)butanamide
Show/Hide
|
C28H32FN3O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0935444
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1-Aminomethyl-6,7,8-trimethoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C16H21ClN2O5
|
1
|
| 1 |
IC50 = 1100 nM
|
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CP0920893
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2-{[3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-7-yl]oxy}acetamide hydrochloride
Show/Hide
|
C22H26ClN3O3
|
1
|
| 1 |
IC50 = 1100 nM
|
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CP0942717
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3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-6-carbonitrile hydrochloride
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 1100 nM
|
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CP0140413
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5-[(3R)-3-aminopiperidin-1-yl]-N-[2-(2,4-dichlorophenyl)ethyl]pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C19H22Cl2N6
|
1
|
| 1 |
IC50 = 1100 nM
|
|
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CP0135279
|
1-N-[5-[(3R)-3-aminopiperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]-4-methylbenzene-1,2-diamine
Show/Hide
|
C18H23N7
|
1
|
| 1 |
IC50 = 1200 nM
|
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CP0734562
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid 4-aminobenzyl amide HCl
Show/Hide
|
C21H23ClF3N5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
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CP0709713
|
(R)-4-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]benzoic acid HCl
Show/Hide
|
C22H22ClF3N4O4
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
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CP0949922
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid HCl
Show/Hide
|
C14H15ClF3N3O3
|
1
|
| 1 |
IC50 = 1400 nM
|
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CP0920894
|
3-[3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yl]propanamide hydrochloride
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0889291
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid phenyl amideHCl
Show/Hide
|
C20H20ClF3N4O2
|
1
|
| 1 |
IC50 = 1600 nM
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CP0903001
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid benzylamide HCl
Show/Hide
|
C21H22ClF3N4O2
|
1
|
| 1 |
IC50 = 1600 nM
|
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CP0939150
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid 4-ethoxycarbonylphenyl ester HCl
Show/Hide
|
C23H23ClF3N3O5
|
1
|
| 1 |
IC50 = 1600 nM
|
|
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CP0956629
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid(4-morpholin-4-ylphenyl)amide HCl
Show/Hide
|
C24H27ClF3N5O3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
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CP0529056
|
3-(aminomethyl)-6-chloro-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0560530
|
N-(2,4-dimethylphenyl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C18H22N6
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0876906
|
(R)-{3-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid ethyl ester HCl
Show/Hide
|
C24H26ClF3N4O5
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
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CP0918937
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid 4-methoxycarbonylmethyl phenyl ester HCl
Show/Hide
|
C23H23ClF3N3O5
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
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CP0426174
|
3-(aminomethyl)-6-chloro-2-(2,2-dimethylpropyl)-4-phenylisoquinolin-1-one
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
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CP0874103
|
3-(Aminomethyl)-N-methyl-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-6-carboxamide hydrochloride
Show/Hide
|
C22H26ClN3O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
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CP0943511
|
(R)-{3-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]phenoxy}acetic acid ethyl ester HCl
Show/Hide
|
C25H28ClF3N4O5
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0858720
|
(R)-{4-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]phenoxy}acetic acid ethyl ester HCl
Show/Hide
|
C25H28ClF3N4O5
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0436126
|
(R)-3-amino-N-(1,4-dibenzylpiperidin-4-yl)-4-(2-fluorophenyl)butanamide
Show/Hide
|
C29H34FN3O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0916746
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid phenyl ester hydrochloride
Show/Hide
|
C20H19ClF3N3O3
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0921928
|
(R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}-(R)-isopropyl acetic acid HCl
Show/Hide
|
C25H28ClF3N4O5
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0967500
|
(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-carbamic acid ethyl ester hydrochloride
Show/Hide
|
C15H20ClN3O4
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0885814
|
1-Aminomethyl-5,8-dimethoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C15H19ClN2O4
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0425421
|
3-(aminomethyl)-6-chloro-4-phenyl-2-propylisoquinolin-1-one
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0452387
|
3-(aminomethyl)-2-butyl-6-chloro-4-phenylisoquinolin-1-one
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0874373
|
3-(Aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-7-carboxamide hydrochloride
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0546083
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(4-chloropyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H18ClN7
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0460058
|
(R)-3-amino-4-(2-fluorophenyl)-N-(4-phenyltetrahydro-2H-pyran-4-yl)butanamide
Show/Hide
|
C21H25FN2O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0877823
|
(R)-{4-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]phenoxy}acetic acid HCl
Show/Hide
|
C23H24ClF3N4O5
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0894408
|
(R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}-(S)-isopropyl acetic acid ethyl ester HCl
Show/Hide
|
C27H32ClF3N4O5
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0858722
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid 4-methoxycarbonylbenzyl ester HCl
Show/Hide
|
C23H23ClF3N3O5
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0939147
|
(R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}-(S)-isopropyl acetic acid HCl
Show/Hide
|
C25H28ClF3N4O5
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0501845
|
4-(7-benzyl-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperazin-1-ium
Show/Hide
|
C18H22N6O2
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0871291
|
(R)-{3-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]phenoxy}acetic acid HCl
Show/Hide
|
C23H24ClF3N4O5
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0443980
|
N-(4-methylpyridin-2-yl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H19N7
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0957059
|
(R)-4-[({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)methyl]benzoic acid methyl ester HCl
Show/Hide
|
C23H24ClF3N4O4
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0422649
|
2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-N-methyl-N-(naphthalen-1-ylmethyl)imidazole-4-carboxamide
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
IC50 = 3059 nM
|
|
|
|
CP0858721
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid4-sulfamoyl benzyl amide HCl
Show/Hide
|
C21H23ClF3N5O4S
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0511946
|
(R)-3-amino-4-(2-fluorophenyl)-N-(4-phenyltetrahydro-2H-thiopyran-4-yl)butanamide
Show/Hide
|
C21H25FN2OS
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0951094
|
1-Aminomethyl-6,7-dimethoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C15H19ClN2O4
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0532217
|
N-(2-nitrophenyl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H17N7O2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0876903
|
(R)-{4-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}-(R)-isopropyl acetic acidethyl ester HCl
Show/Hide
|
C27H32ClF3N4O5
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0956630
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid (1H-benzoimidazol-2-ylmethyl)amide HCl
Show/Hide
|
C22H22ClF3N6O2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0471041
|
3-(aminomethyl)-6-chloro-2-pentyl-4-phenylisoquinolin-1-one
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0458873
|
7-benzyl-3-methyl-8-(piperazin-1-yl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C17H20N6O2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0894523
|
3-(Aminomethyl)-N,N-dimethyl-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-6-carboxamide hydrochloride
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0922704
|
(R)-{3-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid HCl
Show/Hide
|
C22H22ClF3N4O5
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0895237
|
1-Aminomethyl-6-ethoxy-7-methoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C16H21ClN2O4
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0876905
|
(R)-{2-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid ethyl ester HCl
Show/Hide
|
C24H26ClF3N4O5
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0957060
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid amide HCl
Show/Hide
|
C14H16ClF3N4O2
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0140406
|
5-[(3R)-3-aminopiperidin-1-yl]-N-[(2,4-dichlorophenyl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C18H20Cl2N6
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0921929
|
(R)-4-({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)benzoic acid HCl
Show/Hide
|
C21H20ClF3N4O4
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0957208
|
1-Aminomethyl-7-ethoxy-6-methoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C16H21ClN2O4
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
|
CP0871292
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid(pyridin-2-ylmethyl)amide HCl
Show/Hide
|
C20H21ClF3N5O2
|
1
|
| 1 |
IC50 = 7400 nM
|
|
|
|
CP0462730
|
(R)-3-amino-N-(1-benzyl-4-methylpiperidin-4-yl)-4-(2-fluorophenyl)butanamide
Show/Hide
|
C23H30FN3O
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
|
CP0176059
|
4-[[[5-[(3R)-3-aminopiperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]methyl]phenol
Show/Hide
|
C18H22N6O
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0424561
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(4-methylpyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H21N7
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0503416
|
3-(aminomethyl)-6-chloro-2-ethyl-4-phenylisoquinolin-1-one
Show/Hide
|
C18H17ClN2O
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0904746
|
1-Aminomethyl-6-methoxy-7-propoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C17H23ClN2O4
|
1
|
| 1 |
IC50 = 8400 nM
|
|
|
|
CP0922705
|
(R)-{2-[{2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino]phenoxy}acetic acid HCl
Show/Hide
|
C22H22ClF3N4O5
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
|
CP0939149
|
(R)-4-({2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carbonyl}amino)benzenesulfonic acid HCl
Show/Hide
|
C20H20ClF3N4O5S
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0876907
|
(R)-2-[3-Amino-4-(2,4,5-trifluorophenyl)butyryl]-3,4-dihydro-2H-pyrazole-3-carboxylic acid(4-sulfamoyl phenyl)amide HCl
Show/Hide
|
C20H21ClF3N5O4S
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0443976
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C19H24N6
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0560529
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(2-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H19N7O2
|
1
|
| 1 |
IC50 = 11700 nM
|
|
|
|
CP0919834
|
1-Aminomethyl-7-hydroxy-6-methoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C14H17ClN2O4
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0577461
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(4-fluoropyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H18FN7
|
1
|
| 1 |
IC50 = 14400 nM
|
|
|
|
CP0508831
|
3-(aminomethyl)-6-chloro-2-methyl-4-phenylisoquinolin-1-one
Show/Hide
|
C17H15ClN2O
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0856096
|
(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-acetic acid ethyl ester hydrochloride
Show/Hide
|
C16H21ClN2O4
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0577460
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(2,4-difluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H18F2N6
|
1
|
| 1 |
IC50 = 17700 nM
|
|
|
|
CP0911995
|
(E)-3-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-acrylic acid ethyl ester TFA
Show/Hide
|
C19H21F3N2O6
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0920299
|
1-Aminomethyl-5,6,7-trimethoxy-isoquinoline-4-carboxylic acid ethyl ester hydrochloride
Show/Hide
|
C16H21ClN2O5
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0532215
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(2,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H18Cl2N6
|
1
|
| 1 |
IC50 = 22200 nM
|
|
|
|
CP0560531
|
N-(2-chlorophenyl)-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C16H17ClN6
|
1
|
| 1 |
IC50 = 23600 nM
|
|
|
|
CP0176058
|
5-[(3R)-3-aminopiperidin-1-yl]-N-(2-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H19ClN6
|
1
|
| 1 |
IC50 = 25300 nM
|
|
|
|
CP0885946
|
(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-methanol hydrochloride
Show/Hide
|
C13H17ClN2O3
|
1
|
| 1 |
IC50 = 31800 nM
|
|
|
|
CP0958926
|
(R)-5-(3-aminopiperidin-1-yl)-N-(1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H18N8
|
1
|
| 1 |
IC50 = 31800 nM
|
|
|
|
CP0883586
|
1-Aminomethyl-6,7-dimethoxy-isoquinoline-4-carboxylic acid propylamide hydrochloride
Show/Hide
|
C16H22ClN3O3
|
1
|
| 1 |
IC50 = 51400 nM
|
|
|
|
CP0967487
|
3-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-propionic acid ethyl ester TFA
Show/Hide
|
C19H23F3N2O6
|
1
|
| 1 |
IC50 = 52600 nM
|
|
|
|
CP0577462
|
N-methyl-N-phenyl-5-piperazin-1-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C17H20N6
|
1
|
| 1 |
IC50 = 80500 nM
|
|
|
|
CP0893195
|
3-(2-Aminoethyl)-6-chloro-2-methyl-4-phenylisoquinolin-1(2H)-one hydrochloride
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
IC50 = 87000 nM
|
|
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CP0457409
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6-chloro-3-[(dimethylamino)methyl]-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Show/Hide
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C22H25ClN2O
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1
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| 1 |
IC50 > 100000 nM
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CP0459957
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6-chloro-3-(methylaminomethyl)-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Show/Hide
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C21H23ClN2O
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1
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| 1 |
IC50 > 100000 nM
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CP0468330
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3-amino-6-chloro-2-methyl-4-phenylisoquinolin-1-one
Show/Hide
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C16H13ClN2O
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1
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| 1 |
IC50 > 100000 nM
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CP0548615
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6-chloro-3-(hydroxymethyl)-2-methyl-4-phenylisoquinolin-1-one
Show/Hide
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C17H14ClNO2
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1
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| 1 |
IC50 > 100000 nM
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CP0557918
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5-N,7-N-ditert-butylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
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C14H23N5
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1
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| 1 |
IC50 > 100000 nM
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CP0572953
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5-morpholin-4-yl-N-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
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C13H15N7O
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1
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| 1 |
IC50 > 100000 nM
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CP0573412
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5-[(3R)-3-aminopiperidin-1-yl]-N-methyl-N-phenylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
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C18H22N6
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1
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| 1 |
IC50 > 100000 nM
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CP0039344
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(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 2,2,2-trifluoroacetic acid
Show/Hide
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C18H25N3O2
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1
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| 1 |
Ki = 0.6 nM
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CP0141788
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(2S,5R)-5-Ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)-piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki = 1 nM
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CP0214060
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(2S)-1-[(2S)-2-amino-2-cyclopentylacetyl]pyrrolidine-2-carbonitrile
Show/Hide
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C12H19N3O
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1
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| 1 |
Ki = 1 nM
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CP0744509
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(S)-2-(4-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-4-methylpiperidin-1-yl)isonicotinic acid
Show/Hide
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C19H25N5O3
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1
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| 1 |
Ki = 1 nM
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CP0045027
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(2S,5R)-5-ethynyl-1-(N-(4-methyl-1-(5-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl)pyrrolidine-2-carbonitrile
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki = 1.3 nM
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CP0141781
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(2S,5R)-5-ethynyl-1-(N-(4-methyl-1-(5-cyano-pyridin-2-yl)piperidin-4-yl)glycyl)pyrrolidine-2-carbonitrile
Show/Hide
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C21H24N6O
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1
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| 1 |
Ki = 3 nM
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CP0048107
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(2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
Show/Hide
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C17H25N3O2
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1
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| 1 |
Ki = 4 nM
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CP0716878
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(S)-6-(4-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)cyclohexyloxy)nicotinonitrile
Show/Hide
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C19H23N5O2
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1
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| 1 |
Ki = 4 nM
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CP0282994
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(2S,5R)-5-ethynyl-1-{N-(4-trans(5-cyano-pyridin-2-yloxy)cyclohexyl)glycyl}pyrrolidine-2-carbonitrile
Show/Hide
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C21H23N5O2
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1
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| 1 |
Ki = 5 nM
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CP0312025
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(2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C14H19N3O
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1
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| 1 |
Ki = 8 nM
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CP0522906
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(2S,5R)-1-[(2S)-2-amino-4-methylpentanoyl]-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C13H19N3O
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1
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| 1 |
Ki = 8 nM
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CP0312076
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(2S)-1-[2-(tert-butylamino)acetyl]pyrrolidine-2-carbonitrile
Show/Hide
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C11H19N3O
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1
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| 1 |
Ki = 10 nM
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CP0334045
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(2S)-1-[2-(cyclopentylamino)acetyl]pyrrolidine-2-carbonitrile
Show/Hide
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C12H19N3O
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1
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| 1 |
Ki = 11 nM
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CP0282995
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(2S,5R)-1-(N-cyclopentylglycyl)-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C14H19N3O
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1
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| 1 |
Ki = 22 nM
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CP0532148
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(2S,5R)-1-((2S)-2-amino-2-cyclopentylethanoyl)-5-prop-1-ynylpyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O
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1
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| 1 |
Ki = 24 nM
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CP0146197
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(2S,5R)-1-(N-(tert-butyl)glycyl)-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C13H19N3O
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1
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| 1 |
Ki = 25 nM
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CP0897755
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(2S,5S)-1-L-leucyl-5-methylpyrrolidine-2-carbonitrile
Show/Hide
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C12H21N3O
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1
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| 1 |
Ki = 49 nM
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CP0221542
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(2S,5R)-5-ethynyl-1-[N-(3-hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile
Show/Hide
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C19H25N3O2
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1
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| 1 |
Ki = 62 nM
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CP0425388
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(2S,5R)-1-(N-cyclohexylglycyl)-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O
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1
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| 1 |
Ki = 79 nM
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CP0425389
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(2S,5R)-5-ethynyl-1-(N-trans(4-hydroxycyclohexyl)glycyl)pyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O2
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1
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| 1 |
Ki = 90 nM
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CP0522907
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(2S,5R)-1-[(2S)-2-amino-2-cyclohexylacetyl]-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O
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1
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| 1 |
Ki = 96 nM
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CP0897756
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(2S,5S)-1-((2S)-2-amino-2-cyclopentylethanoyl)-5-methylpyrrolidine-2-carbonitrile
Show/Hide
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C13H21N3O
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1
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| 1 |
Ki = 97 nM
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CP0512046
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(2S,5S)-1-[2-(cyclopentylamino)acetyl]-5-methylpyrrolidine-2-carbonitrile
Show/Hide
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C13H21N3O
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1
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| 1 |
Ki = 811 nM
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CP0428228
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(2S,5R)-1-(N-cyclopentylglycyl)-5-prop-1-ynylpyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O
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1
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| 1 |
Ki = 959 nM
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CP0376147
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(2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-ethenylpyrrolidine-2-carbonitrile
Show/Hide
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C14H21N3O
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1
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| 1 |
Ki = 3800 nM
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CP0862384
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(2S,5S)-1-((S)-2-amino-4-methylpentanoyl)-5-phenylpyrrolidine-2-carbonitrile
Show/Hide
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C17H23N3O
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1
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| 1 |
Ki > 30000 nM
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CP0927587
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(2S,5S)-1-((S)-2-amino-2-cyclohexylacetyl)-5-ethynylpyrrolidine-2-carbonitrile
Show/Hide
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C15H21N3O
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1
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| 1 |
Ki > 30000 nM
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