Brief Information of the Cell Line and Protein
Cell Line ID: CL000031 , MDCK
Synonyms
MDCK (NBL-2)
MDCK(NBL-2)
NBL-2
Madin-Darby Canine Kidney
Madin Darby Canine Kidney
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0422
Protein ID: PT01598 , Alpha-2C adrenergic receptor
Gene Name ADRA2C
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P18825
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000031  Protein ID: PT01598
 
Compound ID Compound Name Compound Formula
CP0127400
(-)-Pramipexole
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C10H17N3S
 1
1
Ki = 52.2 nM
   TI
   LI
   LO
   TS
CP0335097
benzyl 5-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate
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C21H25N3O2
 1
1
Ki = 254 nM
   TI
   LI
   LO
   TS
CP0066194
N-[2-(1,3-benzodioxol-5-yl)ethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropan-1-amine
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C28H33NO4
 1
1
Ki = 429 nM
   TI
   LI
   LO
   TS
CP0001212
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
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C23H29N5OS
 1
1
Ki = 433 nM
   TI
   LI
   LO
   TS
CP0168317
1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
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C28H27ClF5NO
 1
1
Ki = 445 nM
   TI
   LI
   LO
   TS
CP0387083
(3aS,9bS)-3a-methyl-5-phenyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
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C18H20N2
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0054519
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
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C25H31F3N2
 1
1
Ki = 1036 nM
   TI
   LI
   LO
   TS
CP0482695
3-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-5-(4-piperidin-4-ylphenyl)benzoic acid
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C24H21ClN4O2S
 1
1
Ki = 1320 nM
   TI
   LI
   LO
   TS
CP0921018
2-((5-Chlorothiophen-2-yl)ethynyl)-N-cyclopentyl-9H-purin-6-amine
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C16H14ClN5S
 1
1
Ki = 1490 nM
   TI
   LI
   LO
   TS
CP0003459
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
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C28H37N5OS
 1
1
Ki = 1557 nM
   TI
   LI
   LO
   TS
CP0225367
benzyl 5-(4-cyclopentylpiperazin-1-yl)-1,3-dihydroisoindole-2-carboxylate
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C25H31N3O2
 1
1
Ki = 1640 nM
   TI
   LI
   LO
   TS
CP0327799
4-(2-benzyl-1,3-dihydroisoindol-5-yl)morpholine
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C19H22N2O
 1
1
Ki = 2466 nM
   TI
   LI
   LO
   TS
CP0137322
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
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C22H25N3O3
 1
1
Ki = 2841 nM
   TI
   LI
   LO
   TS
CP0248165
2-benzyl-5-(3-methoxyphenyl)-1,3-dihydroisoindole
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C22H21NO
 1
1
Ki = 2879 nM
   TI
   LI
   LO
   TS
CP0883983
2-((5-Chlorothiophen-2-yl)ethynyl)-N-(3,4-dihydroxyphenethyl)-9H-purin-6-amine
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C19H14ClN5O2S
 1
1
Ki = 3520 nM
   TI
   LI
   LO
   TS
CP0002070
1-(1H-Indol-3-yl)-2-propanamine
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C11H14N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085414
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
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C20H27NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391120
(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
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C14H21NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391121
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
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C13H19NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391154
(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C14H19NO3
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0411059
(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
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C18H22N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0156479
(+)-N-methyl-laurotetanine
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C20H23NO4
 1
1
Ki > 950 nM
   TI
   LI
   LO
   TS