Brief Information of the Cell Line and Protein
Cell Line ID: CL000028 , PC-12
Synonyms
PC 12
PC12
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_S979
Protein ID: PT02031 , Voltage-dependent N-type calcium channel subunit alpha-1B
Gene Name CACNA1B
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q00975
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000028  Protein ID: PT02031
 
Compound ID Compound Name Compound Formula
CP0860520
2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[4-(2-phenoxy-ethylamino)-piperidin-1-yl]-pentanenitrile oxalic acid
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C31H43N3O7
 2
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0871283
ZICONOTIDE
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C102H172N36O32S7
 2
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
2
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0853789
1-(4-Amino-piperidin-1-yl)-4,4-bis-(4-fluoro-phenyl)-butan-1-one hydrochloride
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C21H25ClF2N2O
 2
1
IC50 = 1030 nM
   TI
   LI
   LO
   TS
2
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0911153
4-Methyl-2-methylamino-pentanoic acid {1-[4,4-bis-(4-fluoro-phenyl)-butyryl]-piperidin-4-yl}-amide hydrochloride
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C28H38ClF2N3O2
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0875086
2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[1-(2-phenoxy-ethyl)-piperidin-4-ylamino]-pentanenitrile hydrochloride
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C29H42ClN3O3
 2
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
2
IC50 = 3800 nM
   TI
   LI
   LO
   TS