| Compound ID |
Compound Name |
Compound Formula |
|
CP0481690
|
N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
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|
C31H23F4N3O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0446824
|
N-[(1S)-1-[4-(3-chlorophenyl)phenyl]ethyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C26H24ClN3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0453891
|
N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-methyl-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamide
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|
C33H27F4N3O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0381392
|
4-(1,8-naphthyridin-2-yl)-N-[1-[4-[3-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide
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|
C27H24F3N3O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0517994
|
3,3,3-trifluoro-N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamide
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|
C32H22F7N3O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0508186
|
N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-methyl-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamide
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|
C32H25F4N3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0534545
|
N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
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|
C31H23F4N3O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0499875
|
2,2-difluoro-N-[(1S)-1-[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]ethyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
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|
C31H21F6N3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0512222
|
N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C26H21F4N3O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0455192
|
N-[[4-(3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C26H25N3O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0516152
|
N-[[4-(3-chloro-4-fluorophenyl)phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
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|
C29H21ClFN3O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0413768
|
3,3,3-trifluoro-N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-hydroxy-2-[4-(1,8-naphthyridin-2-yl)phenyl]propanamide
Show/Hide
|
C31H20F7N3O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0498295
|
N-[[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C23H18F4N4O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0507080
|
N-[[4-(3-chloro-4-fluorophenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C25H21ClFN3O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0381391
|
N-[[4-(3-chlorophenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C25H22ClN3O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0456687
|
2-[4-(3-chlorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-oxadiazole
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|
C25H19ClN4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0512223
|
N-[[2-fluoro-4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C26H21F4N3O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0435902
|
N-[[2-[4-fluoro-3-(trifluoromethyl)phenyl]pyrimidin-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C24H19F4N5O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0449448
|
N-[[3-(3-chlorophenyl)-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C22H19ClN4O2
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0525082
|
N-[[4-(3-ethylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
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|
C27H27N3O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0535905
|
N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
Show/Hide
|
C30H21F4N3O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0517995
|
N-[[3-(3-chloro-4-fluorophenyl)-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C22H18ClFN4O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0553492
|
2-[4-(3-chloro-4-fluorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-oxadiazole
Show/Hide
|
C25H18ClFN4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0446345
|
2-[4-chloro-3-(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
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|
C21H16ClF3N4O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0517996
|
2-[3,4-bis(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
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|
C22H16F6N4O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0426059
|
2-[3-chloro-4-(trifluoromethoxy)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
Show/Hide
|
C21H16ClF3N4O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0426058
|
2-[3-(1,8-naphthyridin-2-yl)propyl]-5-[4-[3-(trifluoromethyl)phenyl]phenyl]-1,3,4-oxadiazole
Show/Hide
|
C26H19F3N4O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0499479
|
N-[[5-[4-fluoro-3-(trifluoromethyl)phenyl]pyrimidin-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C24H19F4N5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0449447
|
N-[[1-[4-fluoro-3-(trifluoromethyl)phenyl]pyrazol-4-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C23H19F4N5O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0462857
|
N-[[5-[4-fluoro-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C22H17F4N5OS
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0486967
|
N-[[4-(4-chloro-3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C26H24ClN3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0513868
|
N-[[4-(3-chlorophenyl)-1,3-thiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C22H19ClN4OS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0534544
|
2-amino-N-[[4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl]methyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
Show/Hide
|
C30H22F4N4O
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0535904
|
4-(1,8-naphthyridin-2-yl)-N-[[4-[3-(trifluoromethoxy)phenyl]phenyl]methyl]butanamide
Show/Hide
|
C26H22F3N3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0515722
|
N-[[2-(3-chlorophenyl)-1,3-thiazol-4-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C22H19ClN4OS
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0435903
|
N-[[6-[4-fluoro-3-(trifluoromethyl)phenyl]pyridazin-3-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C24H19F4N5O
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
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CP0493491
|
methyl 2-fluoro-6-[3-fluoro-4-[[4-(1,8-naphthyridin-2-yl)butanoylamino]methyl]phenyl]benzoate
Show/Hide
|
C27H23F2N3O3
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0446825
|
4-(1,8-naphthyridin-2-yl)-N-[(4-phenylphenyl)methyl]butanamide
Show/Hide
|
C25H23N3O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0493492
|
N-[[4-(3-methoxyphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C26H25N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0523642
|
N-[[5-[4-fluoro-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Show/Hide
|
C22H17F4N5O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0523643
|
2-[3-[3-[4-(3-chloro-4-fluorophenyl)phenyl]-1H-1,2,4-triazol-5-yl]propyl]-1,8-naphthyridine
Show/Hide
|
C25H19ClFN5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0553493
|
2-[4-fluoro-3-(trifluoromethyl)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
Show/Hide
|
C21H16F4N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0435904
|
2-[4-(3-chlorophenyl)phenyl]-5-[3-(1,8-naphthyridin-2-yl)propyl]-1,3,4-thiadiazole
Show/Hide
|
C25H19ClN4S
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0446344
|
2-[4-(1,8-naphthyridin-2-yl)butyl]-5-[4-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0523644
|
2-[4-(1,8-naphthyridin-2-yl)butyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole
Show/Hide
|
C21H17F3N4O
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0523645
|
2-[4-fluoro-3-(trifluoromethoxy)phenyl]-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
Show/Hide
|
C21H16F4N4O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
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CP0514015
|
2-(4-chlorophenyl)-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
Show/Hide
|
C20H17ClN4O
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
