Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT06211 , Free fatty acid receptor 2
Gene Name FFAR2
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q8VCK6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT06211
 
Compound ID Compound Name Compound Formula
CP0408921
(3R)-3-benzyl-4-[cyclopropyl-[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
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C23H20Cl2N2O3S
 1
1
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
CP0412291
(3R)-4-[[4-[5-chloro-2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]-cyclopropylamino]-3-(furan-2-ylmethyl)-4-oxobutanoic acid
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C27H24ClN3O5S
 1
1
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
CP0422648
(3R)-3-(cyclopentylmethyl)-4-[cyclopropyl-[4-[2-(6-pyrazol-1-ylpyridin-3-yl)phenyl]-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
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C30H31N5O3S
 1
1
EC50 = 79.43 nM
   TI
   LI
   LO
   TS
CP0117647
(3R)-3-(cyclopentylmethyl)-4-[cyclopropyl-[4-[2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
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C28H31N3O4S
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0444268
(3R)-3-[cyclopropyl-[4-[2-(6-pyrazol-1-ylpyridin-3-yl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-5-methylhexanoic acid
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C28H29N5O3S
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0387331
(3R)-3-[cyclopropyl-[4-[2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-5-methylhexanoic acid
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C26H29N3O4S
 1
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
CP0426945
(S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide
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C14H15ClN2OS
 1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CP0474752
(3R)-3-benzyl-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-cyclopropylamino]-4-oxobutanoic acid
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C23H21ClN2O3S
 1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CP0532943
(3R)-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-3-(cyclopentylmethyl)-4-oxobutanoic acid
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C20H23ClN2O3S
 1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CP0427201
(3R)-3-benzyl-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-4-oxobutanoic acid
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C21H19ClN2O3S
 1
1
EC50 = 251.19 nM
   TI
   LI
   LO
   TS
CP0412292
(3S)-3-benzyl-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-4-oxobutanoic acid
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C21H19ClN2O3S
 1
1
EC50 = 794.33 nM
   TI
   LI
   LO
   TS
CP0393336
(3R)-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-3-(oxan-4-ylmethyl)-4-oxobutanoic acid
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C20H23ClN2O4S
 1
1
EC50 = 1584.89 nM
   TI
   LI
   LO
   TS