| Compound ID |
Compound Name |
Compound Formula |
|
CP0157955
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxan-2-ylmethyl)piperidin-4-amine
Show/Hide
|
C21H31ClN6O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0390143
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxolan-2-ylmethyl)piperidin-4-amine
Show/Hide
|
C20H29ClN6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0456481
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(naphthalen-1-ylmethyl)piperidin-4-amine
Show/Hide
|
C26H29ClN6
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0175801
|
3-[4-[(2R)-2-[(4-chlorophenyl)methyl]piperidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0220464
|
3-[4-[(2S,4R)-2-[(4-chlorophenyl)methyl]-4-methoxypyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0262465
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2S)-2-methoxypropyl]piperidin-4-amine
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0220465
|
3-[4-[(2S,4S)-2-[(4-chlorophenyl)methyl]-4-methoxypyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0230989
|
3-[4-[(3S)-3-[(4-chlorophenyl)methyl]morpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0258496
|
2-[[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]methyl]phenol
Show/Hide
|
C22H27ClN6O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0369392
|
3-[4-[(2R)-2-[(4-chlorophenyl)methyl]pyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0112463
|
3-[[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]methyl]phenol
Show/Hide
|
C22H27ClN6O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0220467
|
(3S,5S)-1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-5-[(4-chlorophenyl)methyl]pyrrolidin-3-ol
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0352216
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methoxyethyl)piperidin-4-amine
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0075840
|
(3R,5S)-1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-5-[(4-chlorophenyl)methyl]pyrrolidin-3-ol
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0163081
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(4-chlorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0368213
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2-chlorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C22H26Cl2N6
|
2
|
| 1 |
IC50 = 104 nM
|
|
|
| 2 |
IC50 = 149 nM
|
|
|
|
CP0458641
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-ethylpiperidin-4-amine
Show/Hide
|
C17H25BrN6
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0409606
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-benzyl-N-[2-(4-chlorophenyl)ethyl]piperidin-4-amine
Show/Hide
|
C22H27ClN6
|
2
|
| 1 |
IC50 = 122 nM
|
|
|
| 2 |
IC50 = 163 nM
|
|
|
|
CP0437217
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(cyclohexylmethyl)piperidin-4-amine
Show/Hide
|
C22H33ClN6
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0447368
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine
Show/Hide
|
C19H29BrN6
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0434613
|
(2S)-1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]propan-2-ol
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0476153
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H23BrN6
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0258485
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(3-chlorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0220471
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxetan-3-yl)piperidin-4-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0352721
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[(2-chloro-4-fluorophenyl)methyl]-N-[2-(4-chlorophenyl)ethyl]piperidin-4-amine
Show/Hide
|
C22H25Cl2FN6
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0323379
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine
Show/Hide
|
C19H29ClN6
|
3
|
| 1 |
IC50 = 229 nM
|
|
|
| 2 |
IC50 = 232 nM
|
|
|
| 3 |
Ki = 312 nM
|
|
|
|
CP0836935
|
(S)-3-(4-(3-(4-chlorobenzyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C24H30ClN7
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0511392
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2,5-difluorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C22H25ClF2N6
|
1
|
| 1 |
IC50 = 277 nM
|
|
|
|
CP0112464
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[[3-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C23H26ClF3N6
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0109502
|
(2R)-1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]propan-2-ol
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0912045
|
(S)-3-(4-(3-(4-chlorobenzyl)-6-methylene-1,4-oxazepan-4-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C20H27ClN6O
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0238581
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethanol
Show/Hide
|
C17H25ClN6O
|
1
|
| 1 |
IC50 = 384 nM
|
|
|
|
CP0417516
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-ethylpiperidin-4-amine
Show/Hide
|
C17H25ClN6
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
|
CP0417514
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H23ClN6
|
1
|
| 1 |
IC50 = 389 nM
|
|
|
|
CP0075800
|
1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-2-methylpropan-2-ol
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 395 nM
|
|
|
|
CP0773613
|
(S)-3-(4-(7-chloro-3-(4-chlorobenzyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C24H29Cl2N7
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0262463
|
N-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]acetamide
Show/Hide
|
C19H28ClN7O
|
1
|
| 1 |
IC50 = 495 nM
|
|
|
|
CP0363328
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methoxy-2-methylpropyl)piperidin-4-amine
Show/Hide
|
C20H31ClN6O
|
1
|
| 1 |
IC50 = 505 nM
|
|
|
|
CP0238580
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2R)-2-methoxypropyl]piperidin-4-amine
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0365402
|
3-[4-[(2S,3S)-2-[(4-chlorophenyl)methyl]-3-methoxyazetidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0487578
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(3-chloropyridin-4-yl)methyl]piperidin-4-amine
Show/Hide
|
C21H25Cl2N7
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0437223
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-cyclopropylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C19H28N6
|
1
|
| 1 |
IC50 = 765 nM
|
|
|
|
CP0161810
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-N-methylethanesulfonamide
Show/Hide
|
C18H28ClN7O2S
|
1
|
| 1 |
IC50 = 870 nM
|
|
|
|
CP0686385
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H27ClN6O
|
1
|
| 1 |
IC50 = 915 nM
|
|
|
|
CP0801699
|
(S)-3-(4-(3-(4-chlorobenzyl)-7-fluoro-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H26ClFN6O
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0452090
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-propan-2-ylpiperidin-4-amine
Show/Hide
|
C18H27ClN6
|
1
|
| 1 |
IC50 = 945 nM
|
|
|
|
CP0437222
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-ethylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C18H28N6
|
1
|
| 1 |
IC50 = 1011 nM
|
|
|
|
CP0447329
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-propan-2-ylphenyl)ethyl]piperidin-4-amine
Show/Hide
|
C19H30N6
|
1
|
| 1 |
IC50 = 1175 nM
|
|
|
|
CP0157956
|
N-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]methanesulfonamide
Show/Hide
|
C18H28ClN7O2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0220469
|
1-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]-3-methylurea
Show/Hide
|
C19H29ClN8O
|
1
|
| 1 |
IC50 = 1430 nM
|
|
|
|
CP0417517
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-methylphenyl)ethyl]piperidin-4-amine
Show/Hide
|
C17H26N6
|
1
|
| 1 |
IC50 = 1525 nM
|
|
|
|
CP0352217
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-N-methylacetamide
Show/Hide
|
C18H26ClN7O
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0220468
|
3-[4-[3-(4-chlorophenyl)piperidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6
|
1
|
| 1 |
IC50 = 1850 nM
|
|
|
|
CP0220472
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]acetic acid
Show/Hide
|
C17H23ClN6O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0447331
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(2,4-dichlorophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H22Cl2N6
|
1
|
| 1 |
IC50 = 2255 nM
|
|
|
|
CP0912043
|
(S)-3-(4-(7-chloro-3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H26Cl2N6O
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0773610
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydropyrido[3,2-f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C22H26ClN7O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0437221
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-tert-butylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C20H32N6
|
1
|
| 1 |
IC50 = 4160 nM
|
|
|
|
CP0773609
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydropyrido[4,3-f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C22H26ClN7O
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0041008
|
3-[4-[2-(4-bromophenoxy)ethyl]piperazin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C14H19BrN6O
|
1
|
| 1 |
IC50 = 6755 nM
|
|
|
|
CP0808278
|
(S)-4-(1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl)-3-(4-chlorobenzyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-7-carbonitrile
Show/Hide
|
C24H26ClN7O
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0964740
|
(S)-1-(5-amino-1H-1,2,4-triazol-3-yl)-N-(1-(4-chlorophenoxy)-3-(4-chlorophenyl)propan-2-yl)-N-methylpiperidin-4-amine
Show/Hide
|
C23H28Cl2N6O
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0686386
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydropyrido[3,4-f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C22H26ClN7O
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0773612
|
(S)-2-((1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl)(benzyl)amino)-3-(4-chlorophenyl)propan-1-ol
Show/Hide
|
C23H29ClN6O
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0157970
|
3-[4-[3-(4-chlorophenyl)pyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C17H23ClN6
|
1
|
| 1 |
IC50 = 19500 nM
|
|
|
|
CP0773607
|
(S)-3-(4-(7,9-dichloro-3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H25Cl3N6O
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0417510
|
N-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]methyl]-4-bromobenzamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 = 23100 nM
|
|
|
|
CP0417513
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)-N-methylmethanesulfonamide
Show/Hide
|
C15H21BrN6O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0437218
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[(4-bromophenyl)methyl]piperidine-4-carboxamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0437220
|
1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-3-(4-bromophenyl)urea
Show/Hide
|
C14H18BrN7O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0447367
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-2-(4-bromophenyl)acetamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0458642
|
3-[4-[[(4-bromophenyl)methyl-methylamino]methyl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C16H23BrN6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0458649
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)methanesulfonamide
Show/Hide
|
C14H19BrN6O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0478235
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-(2-phenylethyl)piperidin-4-amine
Show/Hide
|
C16H24N6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0478236
|
1-[4-(5-amino-1H-1,2,4-triazol-3-yl)piperazin-1-yl]-2-(4-bromophenoxy)ethanone
Show/Hide
|
C14H17BrN6O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
