| Compound ID |
Compound Name |
Compound Formula |
|
CP0180295
|
4-[[1-(2,4-dichlorophenyl)sulfonyl-3-hydroxyazetidin-3-yl]methoxy]-2-fluorobenzonitrile
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|
C17H13Cl2FN2O4S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 34.1 nM
|
|
|
|
CP0761632
|
4-[1-(2,4-Dichloro-benzenesulfonyl)-4-hydroxy-piperidin-4-ylmethoxy]-benzonitrile
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|
C19H18Cl2N2O4S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 1150 nM
|
|
|
|
CP0468867
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[7-[5-(trifluoromethyl)pyrimidin-2-yl]-3-oxa-7,9-diazabicyclo[3.3.1]nonan-9-yl]methanone
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|
C25H23F3N8O2S2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0417536
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[2-(trifluoromethyl)-4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
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|
C24H20F6N8OS2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0140132
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone
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|
C25H23F3N8OS2
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0470851
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(2S)-2-methyl-4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
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|
C24H23F3N8OS2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0432615
|
[6-[[4-[2-(1-hydroxyethyl)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone
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|
C26H25F3N8O2S2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0471650
|
[6-[[4-(2,5-dimethylpyrazol-3-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone
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|
C25H24F3N9OS
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0495685
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(3S)-3-methyl-4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
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|
C24H23F3N8OS2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0432617
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[8-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-3-yl]methanone
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|
C25H23F3N8OS2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0475174
|
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(2R)-2-methyl-4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
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|
C24H23F3N8OS2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0350860
|
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
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|
C26H28F3N3O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0432616
|
[6-[[3-(1,3-dimethylpyrazol-4-yl)-1,2,4-thiadiazol-5-yl]amino]pyridin-3-yl]-[3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone
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|
C24H23F3N10OS
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0180290
|
9-[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridine-3-carbonyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-one
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|
C21H21N5O3S2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
