| Compound ID |
Compound Name |
Compound Formula |
|
CP0946120
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-ethylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C20H29ClN6O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0839360
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-isobutylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
Show/Hide
|
C22H33ClN6O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0719096
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-isopropylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C21H31ClN6O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0957936
|
((2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)morpholin-2-yl)methanol
Show/Hide
|
C19H27ClN6O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0719098
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-methylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
Show/Hide
|
C19H27ClN6O
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 26.05 nM
|
|
|
|
CP0370214
|
3-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)piperazin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H36ClN7
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0719097
|
2-((2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)morpholin-2-yl)propan-2-ol
Show/Hide
|
C21H31ClN6O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0946531
|
5-(4-((2R,5S)-5-(4-Chlorobenzyl)-2-(methoxymethyl)-morpholino)piperidin-1-yl)-4H-1,2,4-triazol-3-amine
Show/Hide
|
C20H29ClN6O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0956391
|
(2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)-N-methylmorpholine-2-carboxamide
Show/Hide
|
C20H28ClN7O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0230989
|
3-[4-[(3S)-3-[(4-chlorophenyl)methyl]morpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0175801
|
3-[4-[(2R)-2-[(4-chlorophenyl)methyl]piperidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0075840
|
(3R,5S)-1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-5-[(4-chlorophenyl)methyl]pyrrolidin-3-ol
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0686385
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H27ClN6O
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0220464
|
3-[4-[(2S,4R)-2-[(4-chlorophenyl)methyl]-4-methoxypyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0220465
|
3-[4-[(2S,4S)-2-[(4-chlorophenyl)methyl]-4-methoxypyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 345 nM
|
|
|
|
CP0369392
|
3-[4-[(2R)-2-[(4-chlorophenyl)methyl]pyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0220467
|
(3S,5S)-1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-5-[(4-chlorophenyl)methyl]pyrrolidin-3-ol
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0456481
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(naphthalen-1-ylmethyl)piperidin-4-amine
Show/Hide
|
C26H29ClN6
|
1
|
| 1 |
IC50 = 573 nM
|
|
|
|
CP0157955
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxan-2-ylmethyl)piperidin-4-amine
Show/Hide
|
C21H31ClN6O
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0390143
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxolan-2-ylmethyl)piperidin-4-amine
Show/Hide
|
C20H29ClN6O
|
1
|
| 1 |
IC50 = 1080 nM
|
|
|
|
CP0262465
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2S)-2-methoxypropyl]piperidin-4-amine
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0447368
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine
Show/Hide
|
C19H29BrN6
|
1
|
| 1 |
IC50 = 1269 nM
|
|
|
|
CP0409606
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-benzyl-N-[2-(4-chlorophenyl)ethyl]piperidin-4-amine
Show/Hide
|
C22H27ClN6
|
1
|
| 1 |
IC50 = 1508 nM
|
|
|
|
CP0311092
|
3-[4-[(2S)-2-[(4-chlorophenyl)methyl]-4-methylpiperazin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C19H28ClN7
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0352216
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methoxyethyl)piperidin-4-amine
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0955868
|
(S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-3-(4-chlorobenzyl)thiomorpholine-1,1-Dioxide
Show/Hide
|
C18H25ClN6O2S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0437217
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(cyclohexylmethyl)piperidin-4-amine
Show/Hide
|
C22H33ClN6
|
1
|
| 1 |
IC50 = 2025 nM
|
|
|
|
CP0434613
|
(2S)-1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]propan-2-ol
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 2350 nM
|
|
|
|
CP0368213
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2-chlorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
IC50 = 2585 nM
|
|
|
|
CP0476153
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H23BrN6
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0458641
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-ethylpiperidin-4-amine
Show/Hide
|
C17H25BrN6
|
1
|
| 1 |
IC50 = 2715 nM
|
|
|
|
CP0323379
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine
Show/Hide
|
C19H29ClN6
|
2
|
| 1 |
IC50 = 2955 nM
|
|
|
| 2 |
Ki = 3404 nM
|
|
|
|
CP0437223
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-cyclopropylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C19H28N6
|
1
|
| 1 |
IC50 = 3070 nM
|
|
|
|
CP0363328
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methoxy-2-methylpropyl)piperidin-4-amine
Show/Hide
|
C20H31ClN6O
|
1
|
| 1 |
IC50 = 3650 nM
|
|
|
|
CP0075800
|
1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-2-methylpropan-2-ol
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0238581
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethanol
Show/Hide
|
C17H25ClN6O
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0957172
|
(S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)piperazin-2-one
Show/Hide
|
C18H24ClN7O
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0220471
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(oxetan-3-yl)piperidin-4-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0365402
|
3-[4-[(2S,3S)-2-[(4-chlorophenyl)methyl]-3-methoxyazetidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 5550 nM
|
|
|
|
CP0109502
|
(2R)-1-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]propan-2-ol
Show/Hide
|
C18H27ClN6O
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0447329
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-propan-2-ylphenyl)ethyl]piperidin-4-amine
Show/Hide
|
C19H30N6
|
1
|
| 1 |
IC50 = 6965 nM
|
|
|
|
CP0417516
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-ethylpiperidin-4-amine
Show/Hide
|
C17H25ClN6
|
1
|
| 1 |
IC50 = 7080 nM
|
|
|
|
CP0437222
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-ethylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C18H28N6
|
1
|
| 1 |
IC50 = 7121 nM
|
|
|
|
CP0719095
|
5-(4-((2R,5S)-5-(4-Chlorobenzyl)-2-methylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
Show/Hide
|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0417514
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H23ClN6
|
1
|
| 1 |
IC50 = 7470 nM
|
|
|
|
CP0161810
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-N-methylethanesulfonamide
Show/Hide
|
C18H28ClN7O2S
|
1
|
| 1 |
IC50 = 7550 nM
|
|
|
|
CP0262463
|
N-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]acetamide
Show/Hide
|
C19H28ClN7O
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0220469
|
1-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]-3-methylurea
Show/Hide
|
C19H29ClN8O
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0157956
|
N-[2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]ethyl]methanesulfonamide
Show/Hide
|
C18H28ClN7O2S
|
1
|
| 1 |
IC50 = 12500 nM
|
|
|
|
CP0238580
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2R)-2-methoxypropyl]piperidin-4-amine
Show/Hide
|
C19H29ClN6O
|
1
|
| 1 |
IC50 = 12500 nM
|
|
|
|
CP0417517
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-methylphenyl)ethyl]piperidin-4-amine
Show/Hide
|
C17H26N6
|
1
|
| 1 |
IC50 = 12550 nM
|
|
|
|
CP0452090
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-propan-2-ylpiperidin-4-amine
Show/Hide
|
C18H27ClN6
|
1
|
| 1 |
IC50 = 15650 nM
|
|
|
|
CP0220468
|
3-[4-[3-(4-chlorophenyl)piperidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0041008
|
3-[4-[2-(4-bromophenoxy)ethyl]piperazin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C14H19BrN6O
|
1
|
| 1 |
IC50 = 19800 nM
|
|
|
|
CP0220472
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]acetic acid
Show/Hide
|
C17H23ClN6O2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0882792
|
(S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-3-(4-chlorobenzyl)piperazin-2-one
Show/Hide
|
C18H24ClN7O
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0157970
|
3-[4-[3-(4-chlorophenyl)pyrrolidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C17H23ClN6
|
1
|
| 1 |
IC50 = 37000 nM
|
|
|
|
CP0447331
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(2,4-dichlorophenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C16H22Cl2N6
|
1
|
| 1 |
IC50 = 47600 nM
|
|
|
|
CP0352217
|
2-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-[2-(4-chlorophenyl)ethyl]amino]-N-methylacetamide
Show/Hide
|
C18H26ClN7O
|
1
|
| 1 |
IC50 = 48000 nM
|
|
|
|
CP0417510
|
N-[[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]methyl]-4-bromobenzamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0417513
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)-N-methylmethanesulfonamide
Show/Hide
|
C15H21BrN6O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0437218
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[(4-bromophenyl)methyl]piperidine-4-carboxamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0437220
|
1-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-3-(4-bromophenyl)urea
Show/Hide
|
C14H18BrN7O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0437221
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-tert-butylphenyl)ethyl]-N-methylpiperidin-4-amine
Show/Hide
|
C20H32N6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0447367
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-2-(4-bromophenyl)acetamide
Show/Hide
|
C15H19BrN6O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0458642
|
3-[4-[[(4-bromophenyl)methyl-methylamino]methyl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C16H23BrN6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0458649
|
N-[1-(5-amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)methanesulfonamide
Show/Hide
|
C14H19BrN6O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0478235
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-(2-phenylethyl)piperidin-4-amine
Show/Hide
|
C16H24N6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0478236
|
1-[4-(5-amino-1H-1,2,4-triazol-3-yl)piperazin-1-yl]-2-(4-bromophenoxy)ethanone
Show/Hide
|
C14H17BrN6O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
