Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT02767 , Melanin-concentrating hormone receptor 2
Gene Name MCHR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q969V1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT02767
 
Compound ID Compound Name Compound Formula
CP0378079
2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1-yl-quinolin-6-yl)-acetamide
   Show/Hide
C22H22Cl2N4O2
 1
1
IC50 = 3.7 nM
   TI
   LI
   LO
   TS
CP0466897
2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide
   Show/Hide
C23H26Cl2N4O2
 1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
CP0510365
N-[2-(4-aminopiperidin-1-yl)-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C24H25F3N4O3
 1
1
IC50 = 4.7 nM
   TI
   LI
   LO
   TS
CP0494661
N-[4-methyl-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C28H31F3N4O3
 1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CP0485076
(E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-3-(4-trifluoromethoxy-phenyl)-acrylamide
   Show/Hide
C23H22F3N3O3
 1
1
IC50 = 6.4 nM
   TI
   LI
   LO
   TS
CP0391621
N-[2-(2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C24H23F3N4O3
 1
1
IC50 = 6.8 nM
   TI
   LI
   LO
   TS
CP0409389
2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-methylamino-ethyl)-amino]-quinolin-6-yl}-acetamide
   Show/Hide
C22H24Cl2N4O2
 1
1
IC50 = 6.8 nM
   TI
   LI
   LO
   TS
CP0391850
N-[2-[3-(dimethylamino)propylamino]-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C24H27F3N4O3
 1
1
IC50 = 7.1 nM
   TI
   LI
   LO
   TS
CP0466898
(E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-quinolin-6-yl]-3-(4-trifluoromethoxy-phenyl)-acrylamide
   Show/Hide
C24H25F3N4O2
 1
1
IC50 = 8.4 nM
   TI
   LI
   LO
   TS
CP0192469
2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-ethoxy)-4-methyl-quinolin-6-yl]-acetamide
   Show/Hide
C22H23Cl2N3O3
 1
1
IC50 = 8.7 nM
   TI
   LI
   LO
   TS
CP0378080
(E)-N-(4-Methyl-2-piperazin-1-yl-quinolin-6-yl)-3-(4-trifluoromethoxy-phenyl)-acrylamide
   Show/Hide
C24H23F3N4O2
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS
CP0378081
2-(2,4-Dichloro-phenoxy)-N-{2-[(2-hydroxy-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide
   Show/Hide
C21H21Cl2N3O3
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS
CP0378082
Acetic acid 2-({6-[2-(3,4-dichloro-phenoxy)-acetylamino]-4-methyl-quinolin-2-yl}-methyl-amino)-ethyl ester
   Show/Hide
C23H23Cl2N3O4
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS
CP0391852
2-(2,4-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-piperazin-1-yl)-quinolin-6-yl]-acetamide
   Show/Hide
C23H24Cl2N4O2
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS
CP0446449
N-(4-methyl-2-morpholin-4-ylquinolin-6-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C23H22F3N3O4
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS
CP0485075
N-[2-[(1-ethylpyrrolidin-2-yl)methylamino]-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
   Show/Hide
C26H29F3N4O3
 1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS