Compound ID |
Compound Name |
Compound Formula |
CP0048192
|
2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol
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|
C24H40O3
|
1
|
1 |
EC50 = 0.16 nM
|
|
|
CP0397077
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-phenylcyclopropyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C23H19F2N3O
|
1
|
1 |
EC50 = 19 nM
|
|
|
CP0375333
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-2-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H20F2N4O
|
1
|
1 |
EC50 = 43 nM
|
|
|
CP0375332
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C23H21F2N3O
|
1
|
1 |
EC50 = 59 nM
|
|
|
CP0437500
|
6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)quinolin-3-amine
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|
C20H15Cl2FN4O
|
1
|
1 |
EC50 = 77 nM
|
|
|
CP0379011
|
6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)quinoline
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|
C20H14Cl2FN3O2
|
1
|
1 |
EC50 = 83 nM
|
|
|
CP0388581
|
N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]-3-(trifluoromethoxy)quinolin-6-amine
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|
C21H15ClF4N4O2
|
1
|
1 |
EC50 = 130 nM
|
|
|
CP0388674
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-chloroquinolin-3-yl)propanamide
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|
C20H13Cl2FN4O2
|
1
|
1 |
EC50 = 130 nM
|
|
|
CP0388675
|
N-(9-ethylcarbazol-3-yl)-3-[3-(oxan-4-yl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C24H26N4O3
|
1
|
1 |
EC50 = 150 nM
|
|
|
CP0381508
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopentyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C20H21F2N3O2
|
1
|
1 |
EC50 = 150 nM
|
|
|
CP0423248
|
N-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C18H18ClFN4O3
|
1
|
1 |
EC50 = 170 nM
|
|
|
CP0379014
|
3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(6-chloro-1,8-naphthyridin-3-yl)propanamide
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|
C19H12Cl2FN5O2
|
1
|
1 |
EC50 = 220 nM
|
|
|
CP0437003
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl)propanamide
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|
C18H18ClFN6O2S
|
1
|
1 |
EC50 = 220 nM
|
|
|
CP0379012
|
N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]quinolin-6-amine
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|
C20H16ClFN4O
|
1
|
1 |
EC50 = 240 nM
|
|
|
CP0420845
|
3-(3-(2-Cyano-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
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|
C26H20FN5O2
|
1
|
1 |
EC50 = 240 nM
|
|
|
CP0388577
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluoro-2-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C26H23FN4O2
|
1
|
1 |
EC50 = 280 nM
|
|
|
CP0423249
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
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|
C25H20ClFN4O2
|
1
|
1 |
EC50 = 330 nM
|
|
|
CP0396917
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R,2R,4S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C24H27F2N3O
|
1
|
1 |
EC50 = 498 nM
|
|
|
CP0423250
|
2-tert-Butyl-5-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)pyrimidine
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|
C19H20ClFN4O2
|
1
|
1 |
EC50 = 540 nM
|
|
|
CP0388583
|
N-(2-tert-butylpyrimidin-5-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C19H19ClFN5O2
|
1
|
1 |
EC50 = 570 nM
|
|
|
CP0375336
|
(2R,4R)-9-(2,5-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
1 |
EC50 = 639 nM
|
|
|
CP0379010
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C25H21FN4O2
|
1
|
1 |
EC50 = 650 nM
|
|
|
CP0397078
|
(2R,4R)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O
|
1
|
1 |
EC50 = 768 nM
|
|
|
CP0483740
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-fluoro-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H18F3N3O
|
1
|
1 |
EC50 = 855 nM
|
|
|
CP0379008
|
3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butyl)quinoline
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|
C21H17ClFN3O
|
1
|
1 |
EC50 = 1600 nM
|
|
|
CP0474275
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclobutyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C19H19F2N3O2
|
1
|
1 |
EC50 = 1900 nM
|
|
|
CP0397080
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1S)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H19F2N3O2
|
1
|
1 |
EC50 = 5000 nM
|
|
|
CP0396919
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-3-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H20F2N4O
|
1
|
1 |
EC50 = 5400 nM
|
|
|
CP0381504
|
(2S,4S)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O
|
1
|
1 |
EC50 = 8900 nM
|
|
|
CP0155571
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0375335
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-phenyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H21N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0379951
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C19H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0379970
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0381505
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C20H21F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0396918
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C20H21F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0396920
|
(2R,4R)-9-(2,6-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0396921
|
(2R,4R)-9-(2-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H20FN3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0397081
|
(2S,4S)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H17F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0400313
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C17H20N4O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0406642
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrimidin-4-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C16H19N5O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0410471
|
(2R,4R)-9-(3-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H20FN3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0410473
|
(2R,4R)-9-(4-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H20FN3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0410476
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C19H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0410712
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-methyl-1-morpholin-4-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H26F2N4O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0456395
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-3-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H20N4O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0474269
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H19F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0474274
|
(2R,4R)-9-(2,4-dichlorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19Cl2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0483738
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H17F2N3O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0487953
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H19N5O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0379009
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethyl)pyridin-3-yl)propanamide
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|
C17H11ClF4N4O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0388568
|
N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C25H21FN4O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0388576
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)propanamide
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|
C19H11ClF4N4O3S
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0388582
|
5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)isoxazol-3-amine
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|
C18H20ClFN4O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0388584
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-cyano-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)propanamide
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|
C19H12ClF4N5O3
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0388585
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-(trifluoromethyl)phenyl)propanamide
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|
C18H12ClF4N3O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0423239
|
N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)tetrazol-2-yl]propanamide
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|
C24H21FN6O
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0423243
|
5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propylamino)-2-(2,2,2-trifluoroethoxy)nicotinonitrile
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|
C19H14ClF4N5O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0423247
|
3-(3-(3-Cyanopyridin-4-yl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9Hcarbazol-3-yl)propanamide
Show/Hide
|
C25H20N6O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0437503
|
6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)benzo[d]thiazol-2-amine
Show/Hide
|
C18H13Cl2FN4OS
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0457650
|
3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]propanamide
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|
C18H11Cl2F4N3O2
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0456330
|
(2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1,5-a]pyridin-3-yl)methanone
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|
C19H17Cl2N3O2
|
1
|
1 |
IC50 = 1068 nM
|
|
|
CP0442068
|
((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)(6-methylpyridin-3-yl)methanone
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|
C22H26N2O2
|
1
|
1 |
IC50 = 1887 nM
|
|
|
CP0436035
|
N-[[1-(hydroxymethyl)cyclopentyl]methyl]-3-morpholin-4-ylimidazo[1,5-a]pyridine-1-carboxamide
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|
C19H26N4O3
|
1
|
1 |
IC50 > 17000 nM
|
|
|
CP0436298
|
((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)((S)-4-methylmorpholin-3-yl)methanone
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|
C21H30N2O3
|
1
|
1 |
IC50 > 17000 nM
|
|
|