Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01997 , Gonadotropin-releasing hormone receptor
Gene Name GNRHR
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P30969
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01997
 
Compound ID Compound Name Compound Formula
CP0033448
BAY-784
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C29H26ClF4N3O5S2
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0473218
N-[(2-chlorophenyl)methyl]-1-(4-fluorophenyl)sulfonyl-2-methylspiro[2H-indole-3,4'-piperidine]-5-carboxamide
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C27H27ClFN3O3S
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0425867
1'-acetyl-N-[(2-chlorophenyl)methyl]-1-(4-methoxyphenyl)sulfonyl-2-methylspiro[2H-indole-3,4'-piperidine]-5-carboxamide
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C30H32ClN3O5S
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0554164
N-[(3-chloropyridin-2-yl)methyl]-2-cyclopropyl-1-(4-fluorophenyl)sulfonyl-1',1'-dioxospiro[2H-indole-3,4'-thiane]-5-carboxamide
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C28H27ClFN3O5S2
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0491984
N-[(2-chlorophenyl)methyl]-1-(4-methoxyphenyl)sulfonyl-2-methyl-2,3-dihydroindole-5-carboxamide
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C24H23ClN2O4S
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0532999
1-(benzenesulfonyl)-N-[(2-chlorophenyl)methyl]-2,3,3-trimethyl-2H-indole-5-carboxamide
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C25H25ClN2O3S
 1
1
IC50 = 4843 nM
   TI
   LI
   LO
   TS