Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01783 , Endothelin receptor type B
Gene Name EDNRB
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P24530
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01783
 
Compound ID Compound Name Compound Formula
CP0104972
(3S)-3-[[(2S)-2-[[(2S)-2-[[(1S,4S,7S,10R,13S,16R,19S,22R,25R,28R,31S,36R,39S,42R,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-19,22,28-tris(hydroxymethyl)-42-[(4-hydroxyphenyl)methyl]-16-(2-methylpropyl)-13-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-45-propan-2-yl-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecazabicyclo[23.22.4]henpentacontane-36-carbonyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C109H159N25O32S5
 2
1
IC50 = 0.13 nM
   TI
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2
Ki = 0.06 nM
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CP0437617
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-1H-indole-2-carboxylic acid
   Show/Hide
C32H25NO8
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0871246
Sodium salt (Z)-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate
   Show/Hide
C30H29NaO10
 1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CP0278704
3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one
   Show/Hide
C28H26O9
 3
1
IC50 = 120 nM
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2
IC50 = 480 nM
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3
IC50 = 780 nM
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CP0916154
Sodium salt (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate
   Show/Hide
C28H25NaO9
 1
1
IC50 = 130 nM
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   LI
   LO
   TS
CP0466790
5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C26H21NO8S
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0372421
5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-3-methyl-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C30H30O10
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0436750
3-Benzo[1,3]dioxol-5-yl-4-cyclohexylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H26O6
 1
1
IC50 = 225 nM
   TI
   LI
   LO
   TS
CP0448474
5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C27H23NO9S
 1
1
IC50 = 230 nM
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   LI
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   TS
CP0514643
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C29H28O9
 1
1
IC50 = 240 nM
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CP0394167
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(3-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O7
 1
1
IC50 = 260 nM
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CP0409400
5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C29H28O10
 1
1
IC50 = 260 nM
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   TS
CP0449589
1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid
   Show/Hide
C26H21NO8S
 1
1
IC50 = 280 nM
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   TS
CP0522628
1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C28H27NO9S
 1
1
IC50 = 380 nM
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   TS
CP0380276
7-(3,4-Dimethoxy-phenylsulfanyl)-5-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C27H23NO9S
 1
1
IC50 = 420 nM
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CP0391420
5-Benzo[1,3]dioxol-5-ylmethyl-7-(benzo[1,3]dioxol-5-ylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C25H17NO8S
 1
1
IC50 = 420 nM
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   TS
CP0507095
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-triethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C31H32O9
 1
1
IC50 = 445 nM
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CP0454710
1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-6-benzyloxy-5-methoxy-1H-indole-2-carboxylic acid
   Show/Hide
C32H25NO8S
 1
1
IC50 = 490 nM
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   TS
CP0460910
3-Benzo[1,3]dioxol-5-yl-4-cyclopentylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C24H24O6
 1
1
IC50 = 630 nM
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CP0505148
4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O7
 1
1
IC50 = 640 nM
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   TS
CP0445462
7-Benzo[1,3]dioxol-5-yl-5-benzo[1,3]dioxol-5-ylmethyl-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C25H17NO8
 1
1
IC50 = 670 nM
   TI
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   TS
CP0539754
1-Benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-6-methoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C32H27NO7S
 1
1
IC50 = 690 nM
   TI
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   TS
CP0430476
5-Benzo[1,3]dioxol-5-ylmethyl-7-(3-methoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C25H19NO7S
 1
1
IC50 = 760 nM
   TI
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   TS
CP0436917
3-Benzo[1,3]dioxol-5-yl-4-(3,5-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O8
 1
1
IC50 = 760 nM
   TI
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   LO
   TS
CP0496488
1-Benzo[1,3]dioxol-5-ylmethyl-3-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid
   Show/Hide
C27H25NO8
 1
1
IC50 = 850 nM
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CP0449841
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(2,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C28H26O9
 1
1
IC50 = 850 nM
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CP0498651
1-Benzyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C25H23NO5S
 1
1
IC50 = 870 nM
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CP0394350
N-[4-[[4-(1,3-benzodioxol-5-yl)-2-hydroxy-2-(4-methoxyphenyl)-5-oxofuran-3-yl]methyl]phenyl]acetamide
   Show/Hide
C27H23NO7
 1
1
IC50 = 880 nM
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CP0397375
3-Benzo[1,3]dioxol-5-yl-4-(3,4-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O8
 1
1
IC50 = 950 nM
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CP0425308
3-Benzo[1,3]dioxol-5-yl-4-(2,5-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O8
 1
1
IC50 = 1000 nM
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CP0404552
5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C27H25NO8S
 1
1
IC50 = 1100 nM
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CP0505014
1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C26H23NO7S
 1
1
IC50 = 1100 nM
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   TS
CP0449904
2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-3-methyl-butyric acid ethyl ester
   Show/Hide
C36H39NO12
 1
1
IC50 = 1300 nM
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CP0495081
3-Benzo[1,3]dioxol-5-yl-4-cycloheptylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H28O6
 1
1
IC50 = 1300 nM
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   TS
CP0305262
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-1H-indole-2-carboxylic acid
   Show/Hide
C26H21NO8
 1
1
IC50 = 1400 nM
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   TS
CP0436701
4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O7
 1
1
IC50 = 1410 nM
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CP0507299
3-Benzo[1,3]dioxol-5-yl-4-benzo[1,3]dioxol-5-ylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H20O8
 1
1
IC50 = 1500 nM
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   TS
CP0460801
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O7
 1
1
IC50 = 1550 nM
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   TS
CP0381088
1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C32H27NO7S
 1
1
IC50 = 1600 nM
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CP0522001
3-Benzo[1,3]dioxol-5-yl-4-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H22O8
 1
1
IC50 = 1600 nM
   TI
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   TS
CP0531946
4-Benzyl-5-hydroxy-5-(4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H26O7
 1
1
IC50 = 1600 nM
   TI
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CP0449864
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O6
 1
1
IC50 = 1750 nM
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CP0453175
ethyl 2-[[4-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-5-oxo-3-[(3,4,5-trimethoxyphenyl)methyl]furan-2-yl]oxycarbonylamino]acetate
   Show/Hide
C33H33NO12
 1
1
IC50 = 1800 nM
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CP0397940
3-Benzo[1,3]dioxol-5-yl-4-(4-dimethylamino-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H25NO6
 1
1
IC50 = 1800 nM
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CP0374245
3-Benzo[1,3]dioxol-5-yl-4-biphenyl-4-ylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C31H24O6
 1
1
IC50 = 1900 nM
   TI
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CP0921956
Sodium salt (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate
   Show/Hide
C29H27NaO9
 1
1
IC50 = 1900 nM
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   TS
CP0397343
4-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester
   Show/Hide
C27H22O8
 1
1
IC50 = 2000 nM
   TI
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   TS
CP0496557
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(2,3,4-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C28H26O9
 1
1
IC50 = 2000 nM
   TI
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CP0504799
3,5-Bis-benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5H-furan-2-one
   Show/Hide
C25H18O7
 1
1
IC50 = 2000 nM
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   TS
CP0425319
3-Benzo[1,3]dioxol-5-yl-4-(2,3-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O8
 1
1
IC50 = 2200 nM
   TI
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   TS
CP0424312
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-methoxy-1H-indole-2-carboxylic acid
   Show/Hide
C25H19NO7
 1
1
IC50 = 2400 nM
   TI
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   TS
CP0416491
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-1H-indole-2-carboxylic acid
   Show/Hide
C31H23NO7
 1
1
IC50 = 2500 nM
   TI
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   TS
CP0384363
2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-4-methyl-pentanoic acid ethyl ester
   Show/Hide
C37H41NO12
 1
1
IC50 = 2500 nM
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   TS
CP0404152
3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20Cl2O5
 1
1
IC50 = 2700 nM
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   TS
CP0503357
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulfonyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O8S
 1
1
IC50 = 3000 nM
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CP0455701
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-ylmethyl-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C28H21NO6
 1
1
IC50 = 3200 nM
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   TS
CP0496438
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-1H-indole-2-carboxylic acid
   Show/Hide
C24H17NO6
 1
1
IC50 = 3300 nM
   TI
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   TS
CP0403952
4-Benzyl-3-(3,4-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H24O6
 1
1
IC50 = 3900 nM
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   LO
   TS
CP0404460
3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid
   Show/Hide
C31H25NO6
 1
1
IC50 = 4400 nM
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   TS
CP0423209
1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C24H17NO6S
 1
1
IC50 = 4500 nM
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   TS
CP0480743
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(3,4,5-trimethoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O8
 1
1
IC50 = 4500 nM
   TI
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   TS
CP0846693
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H19NaO6
 1
1
IC50 = 4550 nM
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   TS
CP0461125
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O6
 1
1
IC50 = 4550 nM
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   TS
CP0885962
Sodium salt (Z)-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate
   Show/Hide
C29H27NaO10
 1
1
IC50 = 5100 nM
   TI
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   TS
CP0397353
4-Benzyl-3-(3,5-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H24O6
 1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0490197
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-benzyloxy-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C31H24O6
 1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
CP0467553
3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-6-propoxy-1H-indole-2-carboxylic acid
   Show/Hide
C27H23NO7
 1
1
IC50 = 5600 nM
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   TS
CP0424119
3-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester
   Show/Hide
C27H22O8
 1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0522626
1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenylsulfanyl)-6-propoxy-1H-indole-2-carboxylic acid
   Show/Hide
C27H25NO6S
 1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0436523
1,3-Bis-benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1H-indole-2-carboxylic acid
   Show/Hide
C25H19NO8
 1
1
IC50 = 7000 nM
   TI
   LI
   LO
   TS
CP0509187
1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C24H19NO5S
 1
1
IC50 = 7400 nM
   TI
   LI
   LO
   TS
CP0867543
Potassium salt of (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate
   Show/Hide
C27H22KNO7
 1
1
IC50 = 8200 nM
   TI
   LI
   LO
   TS
CP0416642
5-Hydroxy-4-(4-methoxy-benzyl)-3,5-bis-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H24O6
 1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0380407
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-1-ylmethyl)-5H-furan-2-one
   Show/Hide
C34H26O7
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0406386
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-isopropoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O6
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0381770
1,3-Bis-benzo[1,3]dioxol-5-yl-5-propoxy-1H-indole-2-carboxylic acid
   Show/Hide
C26H21NO7
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0507290
4-Benzyl-5-hydroxy-3-(3-methoxy-phenyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H22O5
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0520417
1,3-Bis-benzo[1,3]dioxol-5-yl-5-benzyloxy-1H-indole-2-carboxylic acid
   Show/Hide
C30H21NO7
 1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0403885
3-Benzo[1,3]dioxol-5-yl-1-benzyl-1H-indole-2-carboxylic acid
   Show/Hide
C23H17NO4
 1
1
IC50 = 14500 nM
   TI
   LI
   LO
   TS
CP0573145
1-Benzyl-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C23H19NO3S
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0441189
1,3-Bis-benzo[1,3]dioxol-5-yl-5-methoxy-1H-indole-2-carboxylic acid
   Show/Hide
C24H17NO7
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0496465
3-Benzo[1,3]dioxol-5-yl-4-ethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C20H18O6
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0860431
Sodium salt (Z)-3-benzyl-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate
   Show/Hide
C26H21NaO7
 1
1
IC50 = 15700 nM
   TI
   LI
   LO
   TS
CP0420933
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H22O9
 1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0437650
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-nitro-benzyl)-5H-furan-2-one
   Show/Hide
C25H19NO8
 1
1
IC50 = 17000 nM
   TI
   LI
   LO
   TS
CP0460904
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dimethoxy-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C26H22O7
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0520232
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(3-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O6
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0496518
1-Benzo[1,3]dioxol-5-yl-5-benzyloxy-3-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid
   Show/Hide
C30H23NO6
 1
1
IC50 = 21000 nM
   TI
   LI
   LO
   TS
CP0447210
1,3-Bis-benzo[1,3]dioxol-5-yl-1H-indole-2-carboxylic acid
   Show/Hide
C23H15NO6
 1
1
IC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0913618
(Z)-2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate(2-hydroxy-ethyl)-trimethyl-ammonium
   Show/Hide
C30H33NO7
 1
1
IC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0518219
3-(3-Methoxy-phenylsulfanyl)-benzo[b]thiophene-2-carboxylic acid
   Show/Hide
C16H12O3S2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0539794
3-(3-Methoxy-phenylsulfanyl)-benzofuran-2-carboxylic acid
   Show/Hide
C16H12O4S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0395073
3-Benzo[1,3]dioxol-5-yl-5-methoxy-1-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid
   Show/Hide
C24H19NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0402777
1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(3-methoxy-phenyl)-1H-indole-2-carboxylic acid
   Show/Hide
C24H19NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0404525
1-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-phenyl)-5-methoxy-1H-indole-2-carboxylic acid
   Show/Hide
C25H21NO7
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0408801
1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid
   Show/Hide
C24H19NO6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0420886
3-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid
   Show/Hide
C23H17NO5
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0424125
3-Benzo[1,3]dioxol-5-yl-5-methoxy-1-phenyl-1H-indole-2-carboxylic acid
   Show/Hide
C23H17NO5
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0441190
3-Benzo[1,3]dioxol-5-yl-5-chloro-1-phenyl-1H-indole-2-carboxylic acid
   Show/Hide
C22H14ClNO4
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0492961
3-Benzo[1,3]dioxol-5-yl-6-methoxy-1-phenyl-1H-indole-2-carboxylic acid
   Show/Hide
C23H17NO5
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0392823
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H22O6
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0380749
3-Benzo[1,3]dioxol-5-yl-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C28H26O8
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0409401
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C24H16Cl2O5
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0420839
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3-nitro-benzyl)-5H-furan-2-one
   Show/Hide
C25H19NO8
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0492986
4-Benzyl-3-(2,4-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H24O6
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0510277
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tolyl-5H-furan-2-one
   Show/Hide
C25H20O5
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0404241
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-chloro-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C24H17ClO5
 1
1
IC50 = 27000 nM
   TI
   LI
   LO
   TS
CP0446182
5-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-7-(3-methoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
   Show/Hide
C26H21NO8S
 1
1
IC50 = 29000 nM
   TI
   LI
   LO
   TS
CP0406379
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-phenyl-5H-furan-2-one
   Show/Hide
C24H18O5
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0082372
5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid
   Show/Hide
C19H18O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0534320
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-hydroxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O7
 1
1
IC50 > 250 nM
   TI
   LI
   LO
   TS
CP0372420
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-3-methyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C27H24O7
 1
1
IC50 > 1140 nM
   TI
   LI
   LO
   TS
CP0530853
1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid
   Show/Hide
C34H31NO9S
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0375916
Allyl-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester
   Show/Hide
C32H31NO10
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0392809
((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester
   Show/Hide
C41H37NO10
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0429970
[4-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-5-oxo-3-[(3,4,5-trimethoxyphenyl)methyl]furan-2-yl] N-methylcarbamate
   Show/Hide
C30H29NO10
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0441719
3-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-propionic acid ethyl ester
   Show/Hide
C34H35NO12
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0503989
((S)-1-Phenyl-ethyl)-carbamic acid 4-benzo[1,3]dioxol-5-yl-3-benzyl-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-2-yl ester
   Show/Hide
C34H29NO7
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0374728
4-(4-Benzo[1,3]dioxol-5-yl-3-benzyl-2-hydroxy-5-oxo-2,5-dihydro-furan-2-yl)-benzoic acid methyl ester
   Show/Hide
C26H20O7
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0394370
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O5
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0403942
3-(4-Chloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H21ClO5
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0403943
3-Benzo[1,3]dioxol-5-yl-4-(3,4-dichloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H18Cl2O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0414808
3-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid
   Show/Hide
C26H20O8
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0416709
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(2,4-dimethoxy-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C26H22O7
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0425307
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methylsulfanyl-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O5S
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0437504
3-Benzo[1,3]dioxol-5-yl-4-(4-chloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H19ClO6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0448931
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methyl-benzyl)-5H-furan-2-one
   Show/Hide
C26H22O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0461276
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-ethyl-phenyl)-5-hydroxy-5H-furan-2-one
   Show/Hide
C26H22O5
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0463618
5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-phenyl-5H-furan-2-one
   Show/Hide
C25H22O5
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0466929
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-naphthalen-1-ylmethyl-5H-furan-2-one
   Show/Hide
C29H22O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0480709
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methylsulfanyl-benzyl)-5H-furan-2-one
   Show/Hide
C26H22O6S
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0492161
3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(2-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C25H20O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0498287
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-naphthalen-2-ylmethyl-5H-furan-2-one
   Show/Hide
C29H22O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0498288
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-pyridin-3-ylmethyl-5H-furan-2-one
   Show/Hide
C24H19NO6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0507644
5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-p-tolyl-5H-furan-2-one
   Show/Hide
C26H24O5
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0514477
4-Benzyl-3-(2,5-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one
   Show/Hide
C26H24O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0518243
4-(4-Benzo[1,3]dioxol-5-yl-3-benzyl-2-hydroxy-5-oxo-2,5-dihydro-furan-2-yl)-benzoic acid
   Show/Hide
C25H18O7
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0518299
3-Benzo[1,3]dioxol-5-yl-5-methoxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one
   Show/Hide
C29H28O9
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
CP0534580
3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3-trifluoromethyl-benzyl)-5H-furan-2-one
   Show/Hide
C26H19F3O6
 1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS