Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01776 , Cysteinyl leukotriene receptor 1
Gene Name CYSLTR1
Organism Cavia porcellus, Guinea pig
Protein Classification Membrane receptor
Uniprot ID Q2NNR5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01776
 
Compound ID Compound Name Compound Formula
CP0380609
4-[1-(3-carboxypropyl)-7-[2-[4-[4-(3-fluoro-2-methylphenyl)butoxy]phenyl]ethynyl]-2-methylindol-3-yl]butanoic acid
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C36H38FNO5
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0381577
4-[1-(3-carboxypropyl)-7-[2-[4-[4-(3-chloro-2-methylphenyl)butoxy]phenyl]ethynyl]-2-methylindol-3-yl]butanoic acid
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C36H38ClNO5
 1
1
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
CP0494801
4-[1-(3-carboxypropyl)-2-methyl-7-[2-[4-[4-(2,3,4,6-tetrafluorophenyl)butoxy]phenyl]ethynyl]indol-3-yl]butanoic acid
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C35H33F4NO5
 1
1
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
CP0456062
4-[1-(3-carboxypropyl)-7-[2-[4-[4-(3-chloro-2-methylphenyl)butoxy]phenyl]ethynyl]-4-fluoro-2-methylindol-3-yl]butanoic acid
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C36H37ClFNO5
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0432238
4-[1-(3-carboxypropyl)-4-fluoro-2-methyl-7-[2-[4-[4-(2,3,4,6-tetrafluorophenyl)butoxy]phenyl]ethynyl]indol-3-yl]butanoic acid
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C35H32F5NO5
 1
1
IC50 = 4.3 nM
   TI
   LI
   LO
   TS
CP0427949
4-[1-(3-carboxypropyl)-4-fluoro-7-[2-[4-[4-(3-fluoro-2-methylphenyl)butoxy]phenyl]ethynyl]-2-methylindol-3-yl]butanoic acid
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C36H37F2NO5
 1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS