| Compound ID |
Compound Name |
Compound Formula |
|
CP0421042
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H18N2O2
|
1
|
| 1 |
EC50 = 940 nM
|
|
|
|
CP0440604
|
3-(2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0440605
|
1-methyl-3-(2-nitro-1-phenylethyl)-2-phenylindole
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0440606
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrole
Show/Hide
|
C18H16N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0456939
|
3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0467874
|
3-(2-nitro-1-phenylethyl)-1-phenylindole
Show/Hide
|
C22H18N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0467875
|
2-cyclohexyl-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0491795
|
2-phenyl-2-(2-phenyl-1H-indol-3-yl)ethanamine
Show/Hide
|
C22H20N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0155571
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0483591
|
(NE)-N-[amino-(4-chlorophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H22Cl3N5O2S
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0475901
|
(NE)-N-(1-aminoethylidene)-N'-(4-bromophenyl)sulfonyl-5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C24H21BrClN5O2S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0479894
|
(NE)-N-[amino-(2,4-difluorophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H21Cl2F2N5O2S
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
Ki = 7.7 nM
|
|
|
|
CP0003146
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H21Cl3N4O
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0566949
|
(NE)-N-(1-aminoethylidene)-N'-(4-tert-butylphenyl)sulfonyl-5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C28H30ClN5O2S
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
Ki = 48 nM
|
|
|
|
CP0492771
|
(NE)-N-[amino-(3-methoxyphenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C30H25Cl2N5O3S
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
Ki = 86 nM
|
|
|
|
CP0567160
|
N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]pyridine-2-carboximidamide
Show/Hide
|
C28H22Cl2N6O2S
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
Ki = 26 nM
|
|
|
|
CP0475903
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-4-phenyl-N'-[4-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C25H21ClF3N5O2S
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
Ki = 5.7 nM
|
|
|
|
CP0413327
|
US10787419, Compound 2
Show/Hide
|
C24H21Cl2N5O2S
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0480976
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-(4-iodophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C24H21ClIN5O2S
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0483586
|
methyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-iodophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C24H21ClIN5O2S2
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0480996
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-(4-methoxyphenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C25H24ClN5O3S
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
Ki = 182 nM
|
|
|
|
CP0483593
|
(NE)-N-[amino-(2-fluorophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H22Cl2FN5O2S
|
2
|
| 1 |
IC50 = 72 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0193243
|
(+/-)-SLV319
Show/Hide
|
C23H20Cl2N4O2S
|
2
|
| 1 |
IC50 = 76 nM
|
|
|
| 2 |
Ki = 8.1 nM
|
|
|
|
CP0480997
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-4-phenyl-N'-[4-(trifluoromethoxy)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C25H21ClF3N5O3S
|
2
|
| 1 |
IC50 = 76 nM
|
|
|
| 2 |
Ki = 138 nM
|
|
|
|
CP0513716
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-4-phenyl-N'-(4-propan-2-ylphenyl)sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C27H28ClN5O2S
|
2
|
| 1 |
IC50 = 90 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0413326
|
methyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-[4-(trifluoromethyl)phenyl]sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C25H21ClF3N5O2S2
|
2
|
| 1 |
IC50 = 97 nM
|
|
|
| 2 |
Ki = 63 nM
|
|
|
|
CP0413330
|
(NE)-N-[amino(thiophen-2-yl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C27H21Cl2N5O2S2
|
2
|
| 1 |
IC50 = 101 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0483587
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-(4-methylphenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C25H24ClN5O2S
|
2
|
| 1 |
IC50 = 113 nM
|
|
|
| 2 |
Ki = 87 nM
|
|
|
|
CP0483590
|
(NE)-N-[amino-(4-fluorophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H22Cl2FN5O2S
|
2
|
| 1 |
IC50 = 116 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0483589
|
US10787419, Compound 8
Show/Hide
|
C29H23Cl2N5O2S
|
2
|
| 1 |
IC50 = 117 nM
|
|
|
| 2 |
Ki = 26 nM
|
|
|
|
CP0475902
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-naphthalen-2-ylsulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C28H24ClN5O2S
|
2
|
| 1 |
IC50 = 118 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0413334
|
(NE)-N-(1-amino-2-phenoxyethylidene)-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C30H25Cl2N5O3S
|
2
|
| 1 |
IC50 = 125 nM
|
|
|
| 2 |
Ki = 72 nM
|
|
|
|
CP0479893
|
US10787419, Compound 3
Show/Hide
|
C27H27Cl2N5O2S
|
2
|
| 1 |
IC50 = 182 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0483594
|
benzyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C30H25Cl2N5O2S2
|
2
|
| 1 |
IC50 = 213 nM
|
|
|
| 2 |
Ki = 127 nM
|
|
|
|
CP0413328
|
(NE)-N-[1-adamantyl(amino)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C33H33Cl2N5O2S
|
2
|
| 1 |
IC50 = 226 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0480977
|
US10787419, Compound 4
Show/Hide
|
C26H23Cl2N5O2S
|
2
|
| 1 |
IC50 = 241 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0413329
|
(NE)-N-[amino-(3-bromophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H22BrCl2N5O2S
|
2
|
| 1 |
IC50 = 292 nM
|
|
|
| 2 |
Ki = 56 nM
|
|
|
|
CP0489176
|
methyl N'-[C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C24H21Cl2N5O2S2
|
2
|
| 1 |
IC50 = 329 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0540250
|
propan-2-yl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C26H25Cl2N5O2S2
|
2
|
| 1 |
IC50 = 395 nM
|
|
|
| 2 |
Ki = 166 nM
|
|
|
|
CP0413333
|
2-phenylethyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C31H27Cl2N5O2S2
|
2
|
| 1 |
IC50 = 441 nM
|
|
|
| 2 |
Ki = 287 nM
|
|
|
|
CP0413325
|
ethyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C25H23Cl2N5O2S2
|
2
|
| 1 |
IC50 = 534 nM
|
|
|
| 2 |
Ki = 67 nM
|
|
|
|
CP0483592
|
US10787419, Compound 12
Show/Hide
|
C28H22Cl2N6O2S
|
2
|
| 1 |
IC50 = 603 nM
|
|
|
| 2 |
Ki = 34 nM
|
|
|
|
CP0547350
|
(NE)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-(4-fluorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C24H21ClFN5O2S
|
2
|
| 1 |
IC50 = 686 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0483588
|
(NZ)-N-(1-aminoethylidene)-N'-(benzenesulfonyl)-5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C24H22ClN5O2S
|
2
|
| 1 |
IC50 = 2041 nM
|
|
|
| 2 |
Ki = 114 nM
|
|
|
|
CP0480978
|
3-phenylpropyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-(4-chlorophenyl)sulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C32H29Cl2N5O2S2
|
2
|
| 1 |
IC50 = 2642 nM
|
|
|
| 2 |
Ki = 190 nM
|
|
|
|
CP0413324
|
methyl N'-[(E)-C-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-N-naphthalen-2-ylsulfonylcarbonimidoyl]carbamimidothioate
Show/Hide
|
C28H24ClN5O2S2
|
2
|
| 1 |
IC50 = 2667 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0492772
|
(NE)-N-(1-amino-2-methylpropylidene)-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C26H25Cl2N5O2S
|
2
|
| 1 |
IC50 > 1000 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0483585
|
US10787419, Compound 2E1
Show/Hide
|
C24H21Cl2N5O2S
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0464071
|
(NE)-N-[amino-(4-bromophenyl)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C29H22BrCl2N5O2S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0492770
|
(NZ)-N-[amino-(2,3,4,5-tetrahydropyridin-6-ylamino)methylidene]-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C28H27Cl2N7O2S
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0413335
|
US10787419, Compound 2E2
Show/Hide
|
C24H21Cl2N5O2S
|
1
|
| 1 |
Ki = 671 nM
|
|
|
