Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01549 , Mu-type opioid receptor
Gene Name OPRM1
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P33535
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01549
 
Compound ID Compound Name Compound Formula
CP0913584
N-[cis-4-({2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}amino)cyclohexyl]guanidine dihydrochloride
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C24H30Cl4N6
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0893263
N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C23H30Cl4N4
 1
1
Ki = 120 nM
   TI
   LI
   LO
   TS
CP0913296
(1RS,2SR)-N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}cyclohexane-1,2-diamine dihydrochloride
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C23H27Cl3N4
 1
1
Ki = 150 nM
   TI
   LI
   LO
   TS
CP0858413
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-5-methylquinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C23H30Cl4N4
 1
1
Ki = 170 nM
   TI
   LI
   LO
   TS
CP0913273
(1RS,2RS)-N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}cyclohexane-1,2-diamine dihydrochloride
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C23H28Cl4N4
 1
1
Ki = 180 nM
   TI
   LI
   LO
   TS
CP0941354
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]quinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C22H28Cl4N4
 1
1
Ki = 180 nM
   TI
   LI
   LO
   TS
CP0915591
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-7-methylquinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C23H30Cl4N4
 1
1
Ki = 200 nM
   TI
   LI
   LO
   TS
CP0918606
(1RS,2SR)-N-[2-({2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}amino)cyclohexyl]guanidine dihydrochloride
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C24H30Cl4N6
 1
1
Ki = 220 nM
   TI
   LI
   LO
   TS
CP0941356
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}ethane-1,2-diamine dihydrochloride
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C19H22Cl4N4
 1
1
Ki = 240 nM
   TI
   LI
   LO
   TS
CP0913274
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}butane-1,4-diamine dihydrochloride
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C21H26Cl4N4
 1
1
Ki = 250 nM
   TI
   LI
   LO
   TS
CP0858549
N-[6-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}amino)hexyl]guanidine dihydrochloride
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C24H32Cl4N6
 1
1
Ki = 300 nM
   TI
   LI
   LO
   TS
CP0932751
trans-N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}cyclohexane-1,4-diamine dihydrochloridef
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C23H28Cl4N4
 1
1
Ki = 300 nM
   TI
   LI
   LO
   TS
CP0870110
N-{6-Chloro-2-[(E)-2-(4-chlorophenyl)ethenyl]quinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C22H28Cl6N4
 1
1
Ki = 380 nM
   TI
   LI
   LO
   TS
CP0941355
N-{6-tert-Butyl-2-[(E)-2-(4-chlorophenyl)ethenyl]-quinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C26H36Cl4N4
 1
1
Ki = 380 nM
   TI
   LI
   LO
   TS
CP0858394
cis-N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}cyclohexane-1,4-diamine dihydrochloride
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C23H28Cl4N4
 1
1
Ki = 410 nM
   TI
   LI
   LO
   TS
CP0894551
2-(4-chlorostyryl)-N-(6-aminohexyl)benzo[g]quinazolin-4-amine dihydrochloride
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C26H30Cl4N4
 1
1
Ki = 410 nM
   TI
   LI
   LO
   TS
CP0893262
N-{2-[(E)-2-(4-Chlorophenyl)ethenyl]-8-methylquinazolin-4-yl}hexane-1,6-diamine dihydrochloride
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C23H30Cl4N4
 1
1
Ki = 930 nM
   TI
   LI
   LO
   TS
CP0893264
N-[4-({2-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}amino)butyl]guanidine dihydrochloride
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C22H28Cl4N6
 1
1
Ki = 2300 nM
   TI
   LI
   LO
   TS