Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01374 , T-cell surface glycoprotein CD4
Gene Name CD4
Organism Homo sapiens, Human
Protein Classification Surface antigen
Uniprot ID P01730
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01374
 
Compound ID Compound Name Compound Formula
CP0565034
13-(cyclohexylmethoxy)-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C34H44ClN3O5S2
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0471563
4-[[8-[4-(dimethylamino)phenyl]sulfonyl-13-ethyl-6-methylidene-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-trien-4-yl]sulfonyl]-N,N-dimethylaniline;hydrochloride
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C31H42ClN5O4S2
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0956020
Cyclotriazadisulfonamide Hydrochloride
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C31H40ClN3O4S2
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0426282
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-13-phenylmethoxy-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C34H38ClN3O5S2
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0535097
13-butyl-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C31H40ClN3O4S2
 1
1
IC50 = 540 nM
   TI
   LI
   LO
   TS
CP0532959
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-13-(2-methylpropyl)-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C31H40ClN3O4S2
 1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0532960
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-13-phenyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C33H36ClN3O4S2
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0535151
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-13-propyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C30H38ClN3O4S2
 1
1
IC50 = 830 nM
   TI
   LI
   LO
   TS
CP0492130
13-ethyl-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C29H36ClN3O4S2
 1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
CP0471562
13-tert-butyl-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C31H40ClN3O4S2
 1
1
IC50 = 950 nM
   TI
   LI
   LO
   TS
CP0565033
13-ethoxy-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C29H36ClN3O5S2
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0533279
13-methyl-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C28H34ClN3O4S2
 1
1
IC50 = 1670 nM
   TI
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CP0553227
13-methoxy-6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene;hydrochloride
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C28H34ClN3O5S2
 1
1
IC50 = 1880 nM
   TI
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   TS
CP0533131
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(15),11,13-triene
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C27H31N3O4S2
 1
1
IC50 = 2810 nM
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CP0535150
6-methylidene-4,8-bis-(4-methylphenyl)sulfonyl-4,8,15-triazabicyclo[9.3.1]pentadeca-1(14),11-dien-13-one;hydrobromide
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C27H32BrN3O5S2
 1
1
IC50 = 9300 nM
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   TS