| Compound ID |
Compound Name |
Compound Formula |
|
CP0837174
|
Trans-2',3',4',9'-Tetrahydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'-pyrido[3,4-b]indol]-4-amine Dihydrochloride
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|
C24H30ClN3
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
Ki = 0.19 nM
|
|
|
|
CP0656335
|
trans-6'-Fluoro-4',9'-dihydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
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|
C30H35FN2O8
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0868434
|
trans-6'-Fluoro-4',9'-dihydro-N-methyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
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|
C29H33FN2O8
|
2
|
| 1 |
EC50 = 60 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0858459
|
trans-4',9'-Dihydro-4-(dimethylamino)-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-6'-ol Hemicitrate
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|
C30H36N2O9
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0868687
|
trans-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine 2-hydroxypropane-1,2,3-tricarboxylate
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|
C30H36N2O8
|
1
|
| 1 |
EC50 = 11000 nM
|
|
|
|
CP0868689
|
trans-N4-(2-(1H-indol-3-yl)ethyl)-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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|
C24H33Cl2N3
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0894726
|
1-((trans)-4-(dimethylamino)-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride
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|
C24H34ClN3O
|
2
|
| 1 |
EC50 = 43000 nM
|
|
|
| 2 |
Ki = 1.9 nM
|
|
|
|
CP0764294
|
trans-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine hydrochloride
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|
C24H29ClN2O
|
2
|
| 1 |
Ki = 0.1 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0888228
|
trans-N4-(2-(5-fluoro-1H-indol-3-yl)ethyl)-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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|
C24H32Cl2FN3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0868690
|
3-cyclopentyl-N-((trans)-4-(dimethylamino)-4-phenylcyclohexyl)propanamide hydrochloride
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|
C22H35ClN2O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0868692
|
trans-N1,N1-dimethyl-1-phenyl-N4-(3-phenylpropyl)cyclohexane-1,4-diamine dihydrochloride
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|
C23H34Cl2N2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0958424
|
trans-2',3',4',9'-Tetrahydro-N,N,2'-trimethyl-4-phenyl-spiro[cyclohexane-1,1'-pyrido[3,4-b]-indol]-4-amine Dihydrochloride
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|
C25H32ClN3
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0508735
|
2-hydroxypropane-1,2,3-tricarboxylic acid;N-methyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine
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|
C29H34N2O8
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0456027
|
N,N-dimethyl-1'-phenylspiro[2,3,4,9-tetrahydrocarbazole-1,4'-cyclohexane]-1'-amine
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|
C25H30N2
|
1
|
| 1 |
Ki = 1.26 nM
|
|
|
|
CP0868662
|
trans-4-(2-(1H-indol-3-yl)ethoxy)-N,N-dimethyl-1-phenylcyclohexanamine
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|
C24H30N2O
|
2
|
| 1 |
Ki = 2 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0418728
|
N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-thiopyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine;2-hydroxypropane-1,2,3-tricarboxylic acid
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|
C30H36N2O7S
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0931324
|
trans-4-(dimethylamino)-1-phenethyl-4-phenylcyclohexanol hydrochloride
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|
C22H30ClNO
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0868666
|
trans-4',9'-Dihydro-N,N,6'-trimethyl-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine Hemicitrate
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|
C31H38N2O8
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0451737
|
4-N-(1H-indol-3-ylmethyl)-1-N,1-N-dimethyl-1-phenylcyclohexane-1,4-diamine
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|
C23H29N3
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0508699
|
N-[4-(dimethylamino)-4-phenylcyclohexyl]-2-phenylacetamide;hydrochloride
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|
C22H28N2O
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0910087
|
trans-N1,N1-dimethyl-N4-phenethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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|
C22H32Cl2N2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0921241
|
trans-4',9'-Dihydro-6'-methoxy-N,N-dimethyl-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine Hydrochloride
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|
C25H31ClN2O2
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0910341
|
trans-N4-benzyl-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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|
C21H30Cl2N2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0868691
|
trans-4-(benzyloxy)-N,N-dimethyl-1-phenylcyclohexanamine hydrochloride
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|
C21H28ClNO
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0858238
|
Cis-6'-Fluoro-4',9'-dihydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
Show/Hide
|
C30H35FN2O8
|
1
|
| 1 |
Ki = 97.4 nM
|
|
|
|
CP0908510
|
cis-N,N-dimethyl-1-phenyl-4-(piperidin-1-yl)cyclohexanamine hydrochloride
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|
C19H31ClN2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0419425
|
1-N,1-N-dimethyl-1-phenylcyclohexane-1,4-diamine
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|
C14H22N2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0521467
|
4-(dimethylamino)-1,4-diphenylcyclohexan-1-ol
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|
C20H25NO
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0910342
|
cis-4-(benzyloxy)-N,N-dimethyl-1-phenylcyclohexanamine hydrochloride
Show/Hide
|
C21H28ClNO
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0934489
|
cis-N,N-dimethyl-4-morpholino-1-phenylcyclohexanamine hydrochloride
Show/Hide
|
C18H29ClN2O
|
1
|
| 1 |
Ki = 810 nM
|
|
|
|
CP0894725
|
trans-1-benzyl-4-(dimethylamino)-4-phenylcyclohexanol hydrochloride
Show/Hide
|
C21H28ClNO
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
