| Compound ID |
Compound Name |
Compound Formula |
|
CP0670595
|
Brintonamide D
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|
C48H66N6O10
|
1
|
| 1 |
IC50 = 1790 nM
|
|
|
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CP0854392
|
(S)-methyl 1-((6S,9S,12R)-12-benzyl-6-isobutyl-5,9,11-trimethyl-1-((S)-1-((2R,3S)-3-methyl-2-(3-phenylpropanoyloxy)pentanoyl)pyrrolidin-2-yl)-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxylate
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C48H68N6O10
|
1
|
| 1 |
IC50 = 3220 nM
|
|
|
|
CP0899057
|
Brintonamide E
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C48H66N6O10
|
1
|
| 1 |
IC50 = 4610 nM
|
|
|
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CP0762384
|
Brintonamide C
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|
C50H73N7O10
|
1
|
| 1 |
IC50 = 5510 nM
|
|
|
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CP0219007
|
methyl (2S)-1-[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2R,3S)-2-hydroxy-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]-methylamino]-4-methylpentanoyl]amino]propanoyl]-methylamino]-3-phenylpropanoyl]pyrrolidine-2-carboxylate
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|
C39H60N6O9
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0762370
|
Brintonamide B
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|
C38H58N6O9
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
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CP0883486
|
(S)-methyl 1-((6S,9S,12R)-12-benzyl-6-isobutyl-5,9,11-trimethyl-1-((S)-1-((2R,3S)-3-methyl-2-(3-phenylpropioloyloxy)pentanoyl)pyrrolidin-2-yl)-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxylate
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|
C48H64N6O10
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
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CP0503345
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[(1-oxothian-4-yl)amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C38H44N6O5S
|
1
|
| 1 |
Ki = 0.02512 nM
|
|
|
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CP0458803
|
4-[[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]amino]piperidine-1-sulfonamide
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|
C38H46N8O6S
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
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CP0483786
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[(1-methylsulfonylpiperidin-4-yl)amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C39H47N7O6S
|
1
|
| 1 |
Ki = 0.0631 nM
|
|
|
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CP0512123
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(oxan-4-ylamino)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C38H44N6O5
|
1
|
| 1 |
Ki = 0.0631 nM
|
|
|
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CP0103318
|
(2S,5S,8R)-5-benzyl-8-[(3,4-dichlorophenyl)methyl]-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C33H33Cl2N5O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
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CP0378715
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-sulfamoylpiperazin-1-yl)acetamide
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|
C39H47N9O7S
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
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CP0495703
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(thian-4-ylamino)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C38H44N6O4S
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
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CP0458800
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-hydroxypiperidin-1-yl)acetamide
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|
C40H47N7O6
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
|
CP0502442
|
(2S,5S,8R,12R)-12-(4-acetylpiperazin-1-yl)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C39H45N7O5
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
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CP0307533
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-morpholin-4-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C37H42N6O5
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
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CP0378717
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[methyl(oxan-4-yl)amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C39H46N6O5
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0378718
|
(2S,5S,8R,12R)-5,8-dibenzyl-12-[(1,1-dioxothian-4-yl)amino]-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C38H44N6O6S
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
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CP0378725
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-morpholin-4-ylpiperidin-1-yl)acetamide
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|
C44H54N8O6
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
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CP0503380
|
(2S,5S,8R,12R)-12-amino-5-benzyl-8-[(3,4-dichlorophenyl)methyl]-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C33H34Cl2N6O4
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
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CP0386011
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[(1-methylpiperidin-4-yl)amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C39H47N7O4
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0458797
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(4-piperidin-1-ylpiperidin-1-yl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C43H53N7O4
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0502444
|
(2S,5S,8R,12S)-12-amino-5-benzyl-8-[(3,4-dichlorophenyl)methyl]-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C33H34Cl2N6O4
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
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CP0526291
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(4-morpholin-4-ylpiperidin-1-yl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C42H51N7O5
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
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CP0378713
|
(2S,5S,8R,12R)-5-benzyl-8-[(3,4-dichlorophenyl)methyl]-2-(1H-indol-3-ylmethyl)-12-morpholin-4-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C37H40Cl2N6O5
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
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CP0532402
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-[4-(1-oxo-1,4-thiazinan-4-yl)piperidin-1-yl]acetamide
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|
C44H54N8O6S
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
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CP0365293
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-morpholin-4-ylacetamide
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|
C39H45N7O6
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
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CP0483785
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]acetamide
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|
C40H47N7O6
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
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CP0503381
|
N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(1-oxo-1,4-thiazinan-4-yl)acetamide
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|
C39H45N7O6S
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
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CP0180211
|
4-(4-methylphenyl)-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]benzamide
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|
C41H52N4O4
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
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CP0950400
|
(R)-1-(3-(3-chlorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
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|
C36H47ClN4O4
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
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CP0378710
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(4-methylpiperazin-1-yl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C38H45N7O4
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
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CP0386010
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C39H48N6O9
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
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CP0419822
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N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-piperidin-1-ylpiperidin-1-yl)acetamide
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|
C45H56N8O5
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
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CP0440366
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N-[1-[[(2R)-1-[3-(2-methylpiperidin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
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|
C34H44N4O3S
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
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CP0386009
|
1-[2-[[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]amino]-2-oxoethyl]piperidine-4-carboxamide
Show/Hide
|
C41H48N8O6
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
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CP0526293
|
(2S,5S,8R,12R)-5,8-dibenzyl-12-[[(2S,3S,4S,5R)-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2,3,5,6-tetrahydroxyhexyl]amino]-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C51H68N6O19
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
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CP0928334
|
(R)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)-1-(3-p-tolylacrylamido)cyclopentanecarboxamide
Show/Hide
|
C37H50N4O4
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
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CP0490457
|
(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[[(2S,3R,4S,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexyl]amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
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|
C45H58N6O14
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
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CP0040685
|
N-[1-[[(2R)-1-(3-morpholin-4-ylpropylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H38N4O4S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
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CP0532360
|
(2S,5S,8R,12S)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-morpholin-4-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C37H42N6O5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
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CP0525697
|
N-[1-[[(2R)-1-(3-morpholin-4-ylpropylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H40N4O4S
|
1
|
| 1 |
Ki = 0.7943 nM
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|
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CP0868008
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-(ethylthio)benzamide
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|
C36H50N4O4S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
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CP0915958
|
(R)-1-(3-(3-methoxyphenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C37H50N4O5
|
1
|
| 1 |
Ki = 0.7943 nM
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CP0458798
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(2S,5S,8R,12S)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(oxan-4-ylamino)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C38H44N6O5
|
1
|
| 1 |
Ki = 1 nM
|
|
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CP0844980
|
(R)-1-(3-(2-chlorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C36H47ClN4O4
|
1
|
| 1 |
Ki = 1 nM
|
|
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CP0919506
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(R)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)-1-(3-m-tolylacrylamido)cyclopentanecarboxamide
Show/Hide
|
C37H50N4O4
|
1
|
| 1 |
Ki = 1 nM
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|
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CP0928333
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(R)-1-(3-(4-(methylthio)phenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C37H50N4O4S
|
1
|
| 1 |
Ki = 1 nM
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|
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CP0932422
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(R)-1-(3-(3-fluorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C36H47FN4O4
|
1
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| 1 |
Ki = 1 nM
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|
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CP0458801
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(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-[[(2S,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexyl]amino]-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C45H58N6O14
|
1
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| 1 |
Ki = 1.259 nM
|
|
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CP0485056
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N-[2-[[(2R)-1-oxo-3-phenyl-1-(3-pyrrolidin-1-ylpropylamino)propan-2-yl]carbamoyl]-1,3-dihydroinden-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C35H38N4O3S
|
1
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| 1 |
Ki = 1.259 nM
|
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CP0525698
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N-[1-[[(2R)-1-[3-(dibutylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C36H50N4O3S
|
1
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| 1 |
Ki = 1.259 nM
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|
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CP0878719
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(R)-1-(3-(4-chlorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C36H47ClN4O4
|
1
|
| 1 |
Ki = 1.259 nM
|
|
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CP0949786
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(R)-1-(3-(2-methoxyphenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
|
C37H50N4O5
|
1
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| 1 |
Ki = 1.259 nM
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|
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CP0378712
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(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-piperazin-1-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C37H43N7O4
|
1
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| 1 |
Ki = 1.585 nM
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|
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CP0427667
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N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-methylpiperazin-1-yl)acetamide
Show/Hide
|
C40H48N8O5
|
1
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| 1 |
Ki = 1.585 nM
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CP0458802
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N'-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]butanediamide
Show/Hide
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C45H54N8O11
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1
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| 1 |
Ki = 1.585 nM
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CP0526603
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(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-piperidin-1-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C38H44N6O4
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1
|
| 1 |
Ki = 1.585 nM
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|
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CP0501500
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N-[2-[[(2R)-1-[3-(dibutylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1,3-dihydroinden-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
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C39H48N4O3S
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1
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| 1 |
Ki = 1.585 nM
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CP0849191
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(R)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)-1-(3-o-tolylacrylamido)cyclopentanecarboxamide
Show/Hide
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C37H50N4O4
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1
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| 1 |
Ki = 1.585 nM
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CP0038729
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(2S,5S,8R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C33H35N5O4
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1
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| 1 |
Ki = 1.995 nM
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CP0458796
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(2S,5S,8R,12R)-12-amino-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C33H36N6O4
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1
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| 1 |
Ki = 1.995 nM
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|
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CP0502966
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N-[(2S,3R,4S,5R)-1-[[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]amino]-3,4,5,6-tetrahydroxyhexan-2-yl]acetamide
Show/Hide
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C41H51N7O9
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1
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| 1 |
Ki = 1.995 nM
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CP0440364
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N-[1-[[(2R)-1-[3-(4-methylpiperazin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C32H41N5O3S
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1
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| 1 |
Ki = 1.995 nM
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|
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CP0541542
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N-[2-[[(2R)-1-(3-morpholin-4-ylpropylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1,3-dihydroinden-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
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C35H38N4O4S
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1
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| 1 |
Ki = 1.995 nM
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|
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CP0845499
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(R)-1-(3-(4-methoxyphenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
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C37H50N4O5
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1
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| 1 |
Ki = 1.995 nM
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|
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CP0932335
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(R)-1-(3-(4-fluorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
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C36H47FN4O4
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1
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| 1 |
Ki = 1.995 nM
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|
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CP0509887
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N-[2-[[(2R)-1-[3-(4-methylpiperazin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1,3-dihydroinden-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
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C36H41N5O3S
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1
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| 1 |
Ki = 2.512 nM
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CP0336577
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(2S,5S,8R,13S)-13-amino-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C33H36N6O4
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1
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| 1 |
Ki = 3.162 nM
|
|
|
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CP0458799
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(2S,5S,8R,12S)-12-amino-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C33H36N6O4
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1
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| 1 |
Ki = 3.162 nM
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CP0495700
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(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-(4-methylsulfonylpiperazin-1-yl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C38H45N7O6S
|
1
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| 1 |
Ki = 3.162 nM
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|
|
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CP0927254
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(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-(methylthio)benzamide
Show/Hide
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C35H48N4O4S
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1
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| 1 |
Ki = 3.162 nM
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|
|
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CP0524338
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(2S,3S,4S,5S)-N-[(2S,5S,8R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanamide
Show/Hide
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C45H56N6O15
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1
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| 1 |
Ki = 3.981 nM
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|
|
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CP0440365
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N-[1-[[(2R)-1-[3-(4-methylpiperazin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C33H43N5O3S
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1
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| 1 |
Ki = 3.981 nM
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|
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CP0539654
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N-[1-[[(2R)-1-oxo-3-phenyl-1-(3-pyrrolidin-1-ylpropylamino)propan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C32H40N4O3S
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1
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| 1 |
Ki = 3.981 nM
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CP0914951
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(R)-1-(3-(2-fluorophenyl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
Show/Hide
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C36H47FN4O4
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1
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| 1 |
Ki = 3.981 nM
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|
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CP0919381
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(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-ethoxybenzamide
Show/Hide
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C36H50N4O5
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1
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| 1 |
Ki = 3.981 nM
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|
|
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CP0919507
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(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-3-butoxybenzamide
Show/Hide
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C38H54N4O5
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1
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| 1 |
Ki = 3.981 nM
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|
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CP0419820
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(2S,5S,8R,12R)-12-(4-aminopiperidin-1-yl)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C38H45N7O4
|
1
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| 1 |
Ki = 5.012 nM
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|
|
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CP0855168
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-butylbenzamide
Show/Hide
|
C38H54N4O4
|
1
|
| 1 |
Ki = 5.012 nM
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|
|
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CP0953484
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-3-propoxybenzamide
Show/Hide
|
C37H52N4O5
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1
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| 1 |
Ki = 5.012 nM
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|
|
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CP0495701
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(2S,5S,8R,13S)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-13-(oxan-4-ylamino)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
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C38H44N6O5
|
1
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| 1 |
Ki = 6.31 nM
|
|
|
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CP0428500
|
N-[1-[[(2S)-1-[3-(dibutylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C36H50N4O3S
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1
|
| 1 |
Ki = 6.31 nM
|
|
|
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CP0502443
|
(2S,5S,8R,13R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-13-(oxan-4-ylamino)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C38H44N6O5
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1
|
| 1 |
Ki = 7.943 nM
|
|
|
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CP0541543
|
N-[1-[[(2S)-1-[3-(2-methylpiperidin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C34H44N4O3S
|
1
|
| 1 |
Ki = 7.943 nM
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|
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CP0921352
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-isopropoxybenzamide
Show/Hide
|
C37H52N4O5
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1
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| 1 |
Ki = 7.943 nM
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|
|
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CP0928328
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-propoxybenzamide
Show/Hide
|
C37H52N4O5
|
1
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| 1 |
Ki = 10 nM
|
|
|
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CP0932336
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-isopropylbenzamide
Show/Hide
|
C37H52N4O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0522269
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N-[1-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H40N4O5S
|
1
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| 1 |
Ki = 12.59 nM
|
|
|
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CP0873446
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N-(1-((1-(2-(2-(2-aminoethoxy)ethoxy)ethylamino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)-2,3-dihydro-1H-inden-1-yl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C34H38N4O5S
|
1
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| 1 |
Ki = 12.59 nM
|
|
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CP0950401
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-4-butoxybenzamide
Show/Hide
|
C38H54N4O5
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1
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| 1 |
Ki = 12.59 nM
|
|
|
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CP0490455
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(2S,5S,8R,13R)-13-amino-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Show/Hide
|
C33H36N6O4
|
1
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| 1 |
Ki = 15.85 nM
|
|
|
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CP0954319
|
(R)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)-1-(3-(thiophen-2-yl)acrylamido)cyclopentanecarboxamide
Show/Hide
|
C34H46N4O4S
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1
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| 1 |
Ki = 15.85 nM
|
|
|
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CP0424339
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N-[2-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1,3-dihydroinden-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C34H38N4O5S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
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CP0484224
|
N-[1-[[(2S)-1-oxo-3-phenyl-1-(3-pyrrolidin-1-ylpropylamino)propan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H40N4O3S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
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CP0950402
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-3-ethoxybenzamide
Show/Hide
|
C36H50N4O5
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
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CP0503344
|
(2S)-2-acetamido-N'-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]butanediamide
Show/Hide
|
C47H57N9O12
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
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CP0438969
|
N-[1-[[(2S)-1-(3-morpholin-4-ylpropylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H40N4O4S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
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CP0869895
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-5-butylpicolinamide
Show/Hide
|
C37H53N5O4
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0950359
|
(R)-N-(1-((1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)carbamoyl)cyclopentyl)-3-methoxybenzamide
Show/Hide
|
C35H48N4O5
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
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CP0461906
|
N-[1-[[1-[2-[di(propan-2-yl)amino]ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H44N4O3S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
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CP0458925
|
N-[1-[[(2S)-1-[3-(diethylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H42N4O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
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CP0428496
|
N-[1-[[1-[3-(1-methylpyrrolidin-2-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H42N4O3S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
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CP0439584
|
N-[1-[[(2R)-1-[[(2R)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H38N4O4S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0525699
|
N-[1-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H38N4O5S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
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CP0461907
|
N-[1-[[1-oxo-3-phenyl-1-(2-piperidin-1-ylethylamino)propan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H40N4O3S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0535901
|
N-[1-[[(2S)-1-[[(2R)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H38N4O4S
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
|
CP0433323
|
N-[1-[[1-[2-(diethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H40N4O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0435616
|
N-[1-[[1-(7-aminoheptylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H42N4O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0437107
|
N-[1-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C28H36N4O5S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0461912
|
N-[1-[[1-[3-(diethylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H42N4O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0485058
|
N-[1-[[1-(2-morpholin-4-ylethylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H38N4O4S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0530440
|
N-[1-[[(2S)-1-[3-(4-methylpiperazin-1-yl)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H43N5O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0522403
|
N-[1-[[(2S)-1-[[4-(aminomethyl)phenyl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H36N4O3S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0553254
|
N-[1-[[1-(8-aminooctylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H44N4O3S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0522268
|
N-[1-[[1-(6-aminohexylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H40N4O3S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0435618
|
N-[1-[[(2R)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H38N4O4S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0442477
|
N-[1-[[(2S)-1-(cyclopropylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C28H31N3O3S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0504051
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N-[1-[[(2S)-1-[3-(dimethylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
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C30H38N4O3S
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1
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| 1 |
Ki = 316.23 nM
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CP0525700
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N-[1-[[(2S)-1-(5-aminopentylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
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C30H38N4O3S
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1
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| 1 |
Ki = 398.11 nM
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CP0878444
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N-(2-((1-(2-(2-(2-aminoethoxy)ethoxy)ethylamino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)-1,2,3,4-tetrahydronaphthalen-2-yl)benzo[b]thiophene-2-carboxamide
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C35H40N4O5S
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1
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| 1 |
Ki = 398.11 nM
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CP0458926
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N-[1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclohexyl]-1-benzothiophene-2-carboxamide
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C31H38N4O4S
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1
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| 1 |
Ki = 10000 nM
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CP0915957
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(R)-1-(3-(furan-2-yl)acrylamido)-N-(1-oxo-3-phenyl-1-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methylamino)propan-2-yl)cyclopentanecarboxamide
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C34H46N4O5
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1
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| 1 |
Ki > 100 nM
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CP0522402
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N-[3-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pentan-3-yl]-1-benzothiophene-2-carboxamide
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C30H40N4O5S
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1
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| 1 |
Ki < 1000 nM
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CP0437106
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N-[2-[[(2S)-1-[2-[2-(2-aminoethoxy)ethoxy]ethylamino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-1-benzothiophene-2-carboxamide
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C26H32N4O5S
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1
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| 1 |
Ki < 10000 nM
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