| Compound ID |
Compound Name |
Compound Formula |
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CP0001102
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(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
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C10H13N5O4
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2
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| 1 |
EC50 = 13.49 nM
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|
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| 2 |
IC50 = 1.148 nM
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CP0039348
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(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C12H16N6O4
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2
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| 1 |
EC50 = 14.79 nM
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|
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| 2 |
IC50 = 0.4898 nM
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CP0495143
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-phenoxycyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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C23H28N6O5
|
1
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| 1 |
EC50 = 67.61 nM
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|
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CP0488416
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(2-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C23H27ClN6O5
|
1
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| 1 |
EC50 = 100 nM
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|
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CP0495164
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(4-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C23H27ClN6O5
|
1
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| 1 |
EC50 = 120.23 nM
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|
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CP0488249
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(4-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C21H24ClN5O5
|
1
|
| 1 |
EC50 = 131.83 nM
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|
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CP0488244
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(3-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C21H24ClN5O5
|
1
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| 1 |
EC50 = 154.88 nM
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|
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CP0488422
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(3-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C23H27ClN6O5
|
1
|
| 1 |
EC50 = 162.18 nM
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CP0488425
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(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-(2-chlorophenoxy)cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C21H24ClN5O5
|
1
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| 1 |
EC50 = 186.21 nM
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|
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CP0534813
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(4-tert-butylphenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C27H36N6O5
|
1
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| 1 |
EC50 = 234.42 nM
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|
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CP0527802
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-[(3-methoxyphenyl)methoxy]cyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
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|
C23H29N5O6
|
1
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| 1 |
EC50 = 1047.13 nM
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CP0495148
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(2-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C24H29ClN6O5
|
1
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| 1 |
EC50 = 1412.54 nM
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CP0488424
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(3-chlorophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C24H29ClN6O5
|
1
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| 1 |
EC50 = 1479.11 nM
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|
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CP0488246
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(4-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C24H29BrN6O5
|
1
|
| 1 |
EC50 = 1513.56 nM
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CP0527804
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(1R,2R)-2-phenoxycyclopentyl]amino]purin-9-yl]oxolane-3,4-diol
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|
C21H25N5O5
|
1
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| 1 |
EC50 = 1659.59 nM
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|
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CP0488423
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-[(3-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C24H29BrN6O5
|
1
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| 1 |
EC50 = 2754.23 nM
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CP0494931
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-(3-methoxyphenoxy)cyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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|
C24H30N6O6
|
1
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| 1 |
EC50 = 2754.23 nM
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CP0488250
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(2S,3S,4R,5R)-5-[6-[[(1R,2R)-2-(3-bromophenoxy)cyclopentyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C23H27BrN6O5
|
1
|
| 1 |
EC50 = 3019.95 nM
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CP0495145
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-[(3-methoxyphenyl)methoxy]cyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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|
C25H32N6O6
|
1
|
| 1 |
EC50 = 4168.69 nM
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|
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CP0488245
|
(2R,3R,4S,5R)-2-[6-[[(1R,2R)-2-[(3-bromophenyl)methoxy]cyclopentyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C22H26BrN5O5
|
1
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| 1 |
EC50 = 8317.64 nM
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CP0041613
|
Anapriline
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|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
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| 2 |
IC50 > 5011.87 nM
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CP0066236
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1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
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|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
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| 2 |
IC50 > 5011.87 nM
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CP0366351
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1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
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|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
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| 2 |
IC50 > 5011.87 nM
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CP0018686
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(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
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|
C18H19IN6O4
|
2
|
| 1 |
IC50 = 0.78 nM
|
|
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| 2 |
Ki = 0.72 nM
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CP0385928
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-hydroxycyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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|
C17H24N6O5
|
1
|
| 1 |
IC50 = 2.291 nM
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CP0077413
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(2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
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|
C15H20ClN5O4
|
1
|
| 1 |
IC50 = 11.22 nM
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CP0384628
|
4-[3-(8-methoxy-2,4-dioxo-3-propylpurino[7,8-a]pyridin-1-yl)propylcarbamoyl]benzenesulfonyl fluoride
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|
C23H24FN5O6S
|
2
|
| 1 |
IC50 = 27 nM
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|
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| 2 |
IC50 = 1072 nM
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CP0381923
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(2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
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|
C15H21N5O5
|
1
|
| 1 |
IC50 = 27.54 nM
|
|
|
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CP0381922
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[(3-hydroxy-1-adamantyl)amino]purin-9-yl]oxolane-2-carboxamide
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|
C22H30N6O5
|
1
|
| 1 |
IC50 = 79.43 nM
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CP0397955
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[[(1R,2R)-2-phenylmethoxycyclopentyl]amino]purin-9-yl]oxolane-2-carboxamide
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|
C24H30N6O5
|
1
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| 1 |
IC50 = 269.15 nM
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CP0380753
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7-ethoxy-6-ethyl-3-(4-methyl-1,3-thiazol-2-yl)chromen-4-one
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C17H17NO3S
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0225001
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4-(3,3-Dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide
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|
C16H17F2N3O2S
|
1
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| 1 |
Ki > 10000 nM
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