| Compound ID |
Compound Name |
Compound Formula |
|
CP0061303
|
(2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid
Show/Hide
|
C29H39N5O7
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0469090
|
(1R,5S,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-ol
Show/Hide
|
C22H27NO2
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0088373
|
(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
Show/Hide
|
C28H37N5O7
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0479295
|
ethyl 3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C27H35NO3
|
1
|
| 1 |
EC50 = 49.1 nM
|
|
|
|
CP0444864
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-benzoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H28O8
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0552079
|
3-[(1S,5R,9R)-9-(3-hydroxypropyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Show/Hide
|
C25H33NO2
|
1
|
| 1 |
EC50 = 80.9 nM
|
|
|
|
CP0451330
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-9-(4-methoxybenzoyl)oxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O9
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0444833
|
[(2S,4aR,6aR,7R,10aR,10bR)-7-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromen-9-yl] 3-fluorobenzoate
Show/Hide
|
C28H27FO8
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0479296
|
methyl (E)-3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]prop-2-enoate
Show/Hide
|
C26H31NO3
|
1
|
| 1 |
EC50 = 143 nM
|
|
|
|
CP0444863
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(2-fluorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27FO8
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0444846
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(4-chlorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27ClO8
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0444862
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(4-fluorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27FO8
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0444832
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(4-methylbenzoyl)oxy-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O8
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0401391
|
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-1-methyl-3-piperidinyl]-1H-benzimidazole
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|
C27H42N4
|
2
|
| 1 |
EC50 = 389 nM
|
|
|
| 2 |
Ki = 110 nM
|
|
|
|
CP0401390
|
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3-piperidinyl]-1H-benzimidazole
Show/Hide
|
C26H40N4
|
2
|
| 1 |
EC50 = 514 nM
|
|
|
| 2 |
Ki = 168 nM
|
|
|
|
CP0444865
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-9-(3-methoxybenzoyl)oxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O9
|
1
|
| 1 |
EC50 = 620 nM
|
|
|
|
CP0553129
|
[(2S,4aR,6aR,7R,9S,10aR,10bR)-9-benzamido-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromen-7-yl] acetate
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0444834
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(4-nitrobenzoyl)oxy-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27NO10
|
1
|
| 1 |
EC50 = 770 nM
|
|
|
|
CP0000305
|
(-)-(etorphine)
Show/Hide
|
C17H19NO3
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0386132
|
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1-methyl-3-piperidinyl]-1H-benzimidazole
Show/Hide
|
C27H42N4
|
2
|
| 1 |
EC50 = 2190 nM
|
|
|
| 2 |
Ki > 500 nM
|
|
|
|
CP0386129
|
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole
Show/Hide
|
C26H40N4
|
2
|
| 1 |
EC50 = 4696 nM
|
|
|
| 2 |
Ki > 667 nM
|
|
|
|
CP0469087
|
3-[(1S,5R,9R)-2-(2-phenylethyl)-9-propyl-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Show/Hide
|
C25H33NO
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0469092
|
methyl 3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C26H33NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0479294
|
3-[(1S,5R,9R)-9-[(E)-3-hydroxyprop-1-enyl]-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Show/Hide
|
C25H31NO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0479298
|
methyl 3-[(1S,5R,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C26H33NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0552043
|
3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoic acid
Show/Hide
|
C25H31NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0552077
|
3-[(1R,5S,9S)-9-(3-hydroxypropyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Show/Hide
|
C25H33NO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0552078
|
methyl 3-[(1R,5S,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C26H33NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0036843
|
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester
Show/Hide
|
C23H28O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0036846
|
(3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
Show/Hide
|
C28H30O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
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CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0064900
|
methyl (4aR,5S,8aR)-4-[2-(3,4-dichlorophenyl)acetyl]-5-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
|
C22H29Cl2N3O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0380896
|
1-[(4aR,8S,8aR)-4-benzyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C27H33Cl2N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0429065
|
1-[(4aR,8S,8aS)-8-pyrrolidin-1-yl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C20H27Cl2N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0448281
|
1-[(4aR,8S,8aR)-4-benzyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-phenylethanone
Show/Hide
|
C27H35N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0448282
|
1-[(4aR,8S,8aS)-8-pyrrolidin-1-yl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl]-2-phenylethanone
Show/Hide
|
C20H29N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0399637
|
2-(4,5-dimethoxy-2-pyrrolidin-1-ylsulfonylphenyl)-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C27H37N3O6S
|
1
|
| 1 |
Ki = 0.85 nM
|
|
|
|
CP0041255
|
(+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide
Show/Hide
|
C28H39N3O2
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0508116
|
3-[8-(3-phenylpropyl)-8-azabicyclo[3.2.1]octan-3-yl]phenol
Show/Hide
|
C22H27NO
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0107231
|
3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl]-phenol
Show/Hide
|
C22H29NO
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0380556
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl(propan-2-ylcarbamoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C27H42N4O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0408353
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl-(2-methylsulfonylacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C26H39N3O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
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CP0536346
|
N-[2-[(1R,5S)-3-(3-carbamoylphenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-N-(cyclohexylmethyl)furan-2-carboxamide
Show/Hide
|
C28H37N3O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0435079
|
2-[2-[benzyl(methyl)sulfamoyl]-4,5-dimethoxyphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
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|
C31H39N3O5S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0444103
|
Axelopran sulfate
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|
C26H41N3O8S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0472100
|
3-[(1S,5R)-8-[2-[acetyl(cyclohexylmethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H37N3O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0436372
|
2-(4,5-dimethoxy-2-morpholin-4-ylsulfonylphenyl)-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C27H37N3O7S
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0382973
|
3-[(1S,5R)-8-[2-[cyclohexylmethyl(2,2-dimethylpropanoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C28H43N3O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0437945
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl(dimethylsulfamoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H40N4O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
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CP0437947
|
methyl N-[2-[(1S,5R)-3-(3-carbamoylphenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-N-(cyclohexylmethyl)carbamate
Show/Hide
|
C25H37N3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
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CP0437954
|
3-[(1R,5S)-8-[3-[2-ethylbutyl-(2-hydroxyacetyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H39N3O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
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CP0472099
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl-[2-(2H-tetrazol-5-yl)acetyl]amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C26H37N7O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0440569
|
2-[6-[benzyl(methyl)sulfamoyl]-1,3-benzodioxol-5-yl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C30H35N3O5S
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
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CP0412120
|
3-[(1S,5R)-8-[2-[cyclohexylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H37N3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
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CP0436368
|
2-[4,5-dimethoxy-2-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C28H40N4O6S
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0013111
|
ADL 8-2698
Show/Hide
|
C25H32N2O4
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
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CP0411192
|
3-[(1S,5R)-8-[2-[benzyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
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CP0437953
|
2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3-methylpiperidin-1-yl]propanoyl]amino]acetic acid
Show/Hide
|
C24H30N2O4
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
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CP0462665
|
2-(4,5-dimethoxy-2-pyrrolidin-1-ylsulfonylphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C27H37N3O5S
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0296160
|
(2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-5-oxopentanoic acid
Show/Hide
|
C99H155N31O23
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
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CP0436371
|
2-[6-(dimethylsulfamoyl)-1,3-benzodioxol-5-yl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C24H31N3O6S
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
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CP0048724
|
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
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CP0437948
|
3-[(1S,5R)-8-[2-(cyclohexylmethylamino)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C23H35N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0437946
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl(methylsulfonyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H37N3O3S
|
1
|
| 1 |
Ki = 7.943 nM
|
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CP0399638
|
2-[2-(dimethylsulfamoyl)-4,5-dimethoxyphenyl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C25H35N3O6S
|
1
|
| 1 |
Ki = 9.3 nM
|
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CP0436366
|
2-(4,5-dimethoxy-2-morpholin-4-ylsulfonylphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C27H37N3O6S
|
1
|
| 1 |
Ki = 9.4 nM
|
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CP0386133
|
2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenoxy)ethanol
Show/Hide
|
C29H39N3O2
|
1
|
| 1 |
Ki = 9.5 nM
|
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|
CP0437952
|
3-[(1R,5S)-8-[2-[cyclohexylmethyl-(2,2,2-trifluoroacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H34F3N3O2
|
1
|
| 1 |
Ki = 10 nM
|
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|
CP0437950
|
3-[(1S,5R)-8-[2-[2-ethylbutyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H37N3O3
|
1
|
| 1 |
Ki = 12.59 nM
|
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CP0472098
|
3-[(1S,5R)-8-[2-[(4,4-difluorocyclohexyl)methyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C25H35F2N3O3
|
1
|
| 1 |
Ki = 12.59 nM
|
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CP0437949
|
(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoic acid
Show/Hide
|
C23H29NO3
|
1
|
| 1 |
Ki = 15.85 nM
|
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CP0459481
|
3-[(1S,5R)-8-[2-[cyclopentylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H35N3O3
|
1
|
| 1 |
Ki = 15.85 nM
|
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CP0437944
|
3-[(1S,5R)-8-[5-[2-ethylbutyl-(2-hydroxyacetyl)amino]pentyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C27H43N3O3
|
1
|
| 1 |
Ki = 19.95 nM
|
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CP0437951
|
3-[(1S,5R)-8-[2-[(2-hydroxyacetyl)-(2-phenylethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 19.95 nM
|
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CP0533944
|
3-[(1S,5R)-8-[4-[2-ethylbutyl-(2-hydroxyacetyl)amino]butyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C26H41N3O3
|
1
|
| 1 |
Ki = 19.95 nM
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CP0509939
|
2-[4,5-dimethoxy-2-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C28H40N4O5S
|
1
|
| 1 |
Ki = 23 nM
|
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CP0049540
|
(S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide(ICI 199441)
Show/Hide
|
C21H24Cl2N2O
|
1
|
| 1 |
Ki = 24 nM
|
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CP0437943
|
3-[(1S,5R)-8-[6-[2-ethylbutyl-(2-hydroxyacetyl)amino]hexyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C28H45N3O3
|
1
|
| 1 |
Ki = 25.12 nM
|
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|
|
CP0530787
|
3-[(1S,5R)-8-[2-[(2-hydroxyacetyl)-(3-phenylpropyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
Ki = 31.62 nM
|
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CP0550968
|
3-[(1R,5S)-8-[2-[cyclobutylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C23H33N3O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
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CP0435080
|
2-[2-(dimethylsulfamoyl)-4,5-dimethoxyphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0386130
|
1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(trifluoromethyl)phenyl]-1H-benzimidazole
Show/Hide
|
C28H34F3N3
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0437955
|
3-[(1S,5R)-8-[2-[hexyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H37N3O3
|
1
|
| 1 |
Ki = 63.1 nM
|
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|
|
CP0038839
|
(4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
Ki = 103 nM
|
|
|
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CP0491131
|
US8846929, 300
Show/Hide
|
C33H40N4O4
|
1
|
| 1 |
Ki = 106 nM
|
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|
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CP0478166
|
2-[6-(dimethylsulfamoyl)-1,3-benzodioxol-5-yl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C24H31N3O5S
|
1
|
| 1 |
Ki = 110 nM
|
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CP0372876
|
1-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenyl)methanamine
Show/Hide
|
C28H38N4
|
1
|
| 1 |
Ki = 140 nM
|
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CP0536345
|
3-[(1R,5S)-8-[2-[(2-hydroxyacetyl)-(oxan-4-ylmethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H35N3O4
|
1
|
| 1 |
Ki = 199.53 nM
|
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CP0377809
|
(1-{4-[2-(4-Chlorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C27H34ClN3O
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0377805
|
[1-[4-[2-(2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctyl]methanol
Show/Hide
|
C34H47N5O
|
1
|
| 1 |
Ki = 258 nM
|
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CP0376883
|
methyl 1-[4-[2-(4-methylpiperazin-1-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctane-1-carboxylate
Show/Hide
|
C27H41N5O2
|
1
|
| 1 |
Ki = 312 nM
|
|
|
|
CP0503758
|
US8846929, 354
Show/Hide
|
C30H39N3O3
|
1
|
| 1 |
Ki = 386 nM
|
|
|
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CP0435078
|
2-(3,4-dimethoxyphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0261931
|
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one
Show/Hide
|
C21H26NO4+
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0880333
|
METHYLNALTREXONE BROMIDE
Show/Hide
|
C21H26BrNO4
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0436370
|
2-(1,3-benzodioxol-5-yl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0510256
|
US8846929, 304
Show/Hide
|
C23H31N3O3
|
1
|
| 1 |
Ki = 667 nM
|
|
|
|
CP0376884
|
(1-{4-[2-(4-Methylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C26H41N5O
|
1
|
| 1 |
Ki = 679 nM
|
|
|
|
CP0086136
|
US8476271, 405
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
Ki = 691 nM
|
|
|
|
CP0432046
|
N,N-diethyl-4-[[(1R,5R)-4-phenyl-8-prop-2-enyl-6,8-diazabicyclo[3.2.2]non-3-en-6-yl]methyl]benzamide
Show/Hide
|
C28H35N3O
|
1
|
| 1 |
Ki = 740 nM
|
|
|
|
CP0491120
|
US8846929, 364
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
Ki = 758 nM
|
|
|
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CP0491119
|
US8846929, 359
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 1011 nM
|
|
|
|
CP0426466
|
US8846929, 303
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
Ki = 1102 nM
|
|
|
|
CP0529291
|
US8846929, 353
Show/Hide
|
C31H45N5O3
|
1
|
| 1 |
Ki = 1159 nM
|
|
|
|
CP0413770
|
(2S)-1-[(2S)-2-(2-aminodecanoylamino)-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C66H89N11O10S
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0469759
|
US8846929, 176
Show/Hide
|
C30H42N4O3
|
1
|
| 1 |
Ki = 1305 nM
|
|
|
|
CP0443715
|
US8846929, 301
Show/Hide
|
C26H37N3O3
|
1
|
| 1 |
Ki = 1396 nM
|
|
|
|
CP0529481
|
US9290488, E54a
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
Ki = 1510 nM
|
|
|
|
CP0413120
|
US9290488, B21a
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 1516 nM
|
|
|
|
CP0483219
|
US8846929, 298
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 1523 nM
|
|
|
|
CP0376671
|
(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H70N10O9S
|
1
|
| 1 |
Ki = 1557 nM
|
|
|
|
CP0520136
|
US8846929, 294
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 1606 nM
|
|
|
|
CP0518184
|
US9090618, ZA26
Show/Hide
|
C23H35N5O
|
1
|
| 1 |
Ki = 1616 nM
|
|
|
|
CP0466707
|
US8846929, 120
Show/Hide
|
C31H39N5O3
|
1
|
| 1 |
Ki = 1710 nM
|
|
|
|
CP0470339
|
US8846929, 352
Show/Hide
|
C33H40N4O4
|
1
|
| 1 |
Ki = 1743 nM
|
|
|
|
CP0519422
|
US9290488, E53a(i)
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
Ki = 1770 nM
|
|
|
|
CP0544765
|
US8846929, 209
Show/Hide
|
C32H40N4O3
|
1
|
| 1 |
Ki = 1870 nM
|
|
|
|
CP0513748
|
US8846929, 296
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 1970 nM
|
|
|
|
CP0381394
|
(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C47H61N9O8S
|
1
|
| 1 |
Ki = 1977 nM
|
|
|
|
CP0205889
|
US8476271, 19
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 2027 nM
|
|
|
|
CP0491117
|
US8846929, 309
Show/Hide
|
C29H40N4O4S
|
1
|
| 1 |
Ki = 2045 nM
|
|
|
|
CP0557348
|
US8846929, 292
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 2141 nM
|
|
|
|
CP0529285
|
US8846929, 313
Show/Hide
|
C30H42N4O4
|
1
|
| 1 |
Ki = 2220 nM
|
|
|
|
CP0484873
|
(2S)-1-[(2S)-2-(2-aminodecanoylamino)-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C57H80N10O9S
|
1
|
| 1 |
Ki = 2254 nM
|
|
|
|
CP0442040
|
US8846929, 311
Show/Hide
|
C32H38N4O4
|
1
|
| 1 |
Ki = 2570 nM
|
|
|
|
CP0544987
|
US9290488, B12a
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
Ki = 2620 nM
|
|
|
|
CP0442038
|
US8846929, 84
Show/Hide
|
C29H36N4O3
|
1
|
| 1 |
Ki = 2712 nM
|
|
|
|
CP0543998
|
US8846929, 201
Show/Hide
|
C28H37N5O4
|
1
|
| 1 |
Ki = 2740 nM
|
|
|
|
CP0235395
|
(S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C34H38N6O5
|
1
|
| 1 |
Ki = 2765 nM
|
|
|
|
CP0443720
|
US8846929, 366
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
Ki = 2856 nM
|
|
|
|
CP0443717
|
US8846929, 302
Show/Hide
|
C25H35N3O3
|
1
|
| 1 |
Ki = 2863 nM
|
|
|
|
CP0517947
|
US8637502, 6
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
Ki = 2900 nM
|
|
|
|
CP0540038
|
US9290488, A11a(i)
Show/Hide
|
C29H38N4O3
|
1
|
| 1 |
Ki = 3050 nM
|
|
|
|
CP0470955
|
US8846929, 290
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 3155 nM
|
|
|
|
CP0437956
|
3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoic acid
Show/Hide
|
C16H23NO3
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0519421
|
US9290488, B20a(i)
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 3440 nM
|
|
|
|
CP0529482
|
US9290488, B20a(ii)
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 3920 nM
|
|
|
|
CP0412096
|
US9090618, ZA37
Show/Hide
|
C27H36N4O3
|
1
|
| 1 |
Ki = 3960 nM
|
|
|
|
CP0402464
|
US9290488, B34a
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
Ki = 3990 nM
|
|
|
|
CP0418230
|
US8637502, 12
Show/Hide
|
C25H23N3O2
|
1
|
| 1 |
Ki = 4050 nM
|
|
|
|
CP0556941
|
US9090618, ZA70
Show/Hide
|
C29H38ClN5
|
1
|
| 1 |
Ki = 4170 nM
|
|
|
|
CP0411821
|
2-(3,4-dichlorophenyl)-1-[4-(pyridin-2-ylmethyl)-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
|
C26H32Cl2N4O
|
1
|
| 1 |
Ki = 4300 nM
|
|
|
|
CP0383582
|
US8846929, 99
Show/Hide
|
C29H40N4O3
|
1
|
| 1 |
Ki = 4470 nM
|
|
|
|
CP0530685
|
US9290488, K29b
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
Ki = 4470 nM
|
|
|
|
CP0109897
|
US8846929, 362
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 4763 nM
|
|
|
|
CP0445196
|
US9290488, E53a(ii)
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
Ki = 4860 nM
|
|
|
|
CP0450784
|
US8846929, 314
Show/Hide
|
C32H38N4O4
|
1
|
| 1 |
Ki = 4925 nM
|
|
|
|
CP0538967
|
US9090618, H30b(ii)
Show/Hide
|
C31H44N4O2
|
1
|
| 1 |
Ki = 5275 nM
|
|
|
|
CP0399430
|
US8846929, 336
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 5437 nM
|
|
|
|
CP0462642
|
US8637502, 24
Show/Hide
|
C27H26N4O3
|
1
|
| 1 |
Ki = 5450 nM
|
|
|
|
CP0514985
|
US9090618, ZA28
Show/Hide
|
C22H34N6O
|
1
|
| 1 |
Ki = 5655 nM
|
|
|
|
CP0957896
|
US9090618, ZA69
Show/Hide
|
C28H37N5
|
1
|
| 1 |
Ki = 6160 nM
|
|
|
|
CP0507886
|
US9290488, L2b(i)
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
Ki = 6410 nM
|
|
|
|
CP0450789
|
US8846929, 38
Show/Hide
|
C29H36N4O
|
1
|
| 1 |
Ki = 6673 nM
|
|
|
|
CP0450741
|
US9090618, H56b(i)
Show/Hide
|
C32H46N4O2
|
1
|
| 1 |
Ki = 6790 nM
|
|
|
|
CP0510257
|
US8846929, 363
Show/Hide
|
C27H33N3O3
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0503752
|
US8846929, 8
Show/Hide
|
C30H45N5O3
|
1
|
| 1 |
Ki = 7556 nM
|
|
|
|
CP0529483
|
US9290488, C20a(ii)
Show/Hide
|
C30H38N4O4
|
1
|
| 1 |
Ki = 7670 nM
|
|
|
|
CP0450785
|
US8846929, 318
Show/Hide
|
C31H37N5O4
|
1
|
| 1 |
Ki = 7730 nM
|
|
|
|
CP0568166
|
US9290488, B11a(ii)
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
Ki = 8000 nM
|
|
|
|
CP0124715
|
N-(4-amino-2-methylquinolin-6-yl)-2-[(4-ethylphenoxy)methyl]benzamide
Show/Hide
|
C26H25N3O2
|
1
|
| 1 |
Ki = 8647.2 nM
|
|
|
|
CP0491129
|
US8846929, 310
Show/Hide
|
C28H36N4O6
|
1
|
| 1 |
Ki = 8680 nM
|
|
|
|
CP0443712
|
US8846929, 337
Show/Hide
|
C29H41N5O3
|
1
|
| 1 |
Ki = 8840 nM
|
|
|
|
CP0554260
|
US8846929, 196
Show/Hide
|
C28H38N4O4
|
1
|
| 1 |
Ki = 8880 nM
|
|
|
|
CP0279176
|
US8476271, 18
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 8900 nM
|
|
|
|
CP0464914
|
US8846929, 4
Show/Hide
|
C32H47N5O3
|
1
|
| 1 |
Ki = 8918 nM
|
|
|
|
CP0524500
|
US8637502, 9
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 9600 nM
|
|
|
|
CP0529288
|
US8846929, 86
Show/Hide
|
C21H31N3O
|
1
|
| 1 |
Ki = 9670 nM
|
|
|
|
CP0399423
|
US8846929, 83
Show/Hide
|
C23H32N4O3
|
1
|
| 1 |
Ki = 10177 nM
|
|
|
|
CP0529179
|
US9090618, ZA27
Show/Hide
|
C21H31N5O
|
1
|
| 1 |
Ki = 10260 nM
|
|
|
|
CP0402513
|
US9090618, ZA25
Show/Hide
|
C31H45N5O2
|
1
|
| 1 |
Ki = 10900 nM
|
|
|
|
CP0483216
|
US8846929, 241
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 10900 nM
|
|
|
|
CP0551139
|
US8846929, 6
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 11122 nM
|
|
|
|
CP0903202
|
US8846929, 351
Show/Hide
|
C30H38N6O4
|
1
|
| 1 |
Ki = 11275 nM
|
|
|
|
CP0464044
|
US8846929, 189
Show/Hide
|
C30H40N6O3
|
1
|
| 1 |
Ki = 11430 nM
|
|
|
|
CP0402465
|
US9290488, A11a(ii)
Show/Hide
|
C29H38N4O3
|
1
|
| 1 |
Ki = 11500 nM
|
|
|
|
CP0484123
|
US9090618, O85d
Show/Hide
|
C34H48N4O4
|
1
|
| 1 |
Ki = 12140 nM
|
|
|
|
CP0531780
|
US8846929, 308
Show/Hide
|
C28H38N4O4
|
1
|
| 1 |
Ki = 12160 nM
|
|
|
|
CP0445197
|
US9290488, L2b(ii)
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
Ki = 12500 nM
|
|
|
|
CP0466570
|
US8846929, 106
Show/Hide
|
C25H34N4O3
|
1
|
| 1 |
Ki = 12882 nM
|
|
|
|
CP0491126
|
US8846929, 70
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
Ki = 13080 nM
|
|
|
|
CP0442036
|
US8846929, 69
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
Ki = 13091 nM
|
|
|
|
CP0569075
|
US8846929, 121
Show/Hide
|
C25H34N4O3
|
1
|
| 1 |
Ki = 13563 nM
|
|
|
|
CP0479195
|
US9090618, ZA33
Show/Hide
|
C27H40N4O2
|
1
|
| 1 |
Ki = 13600 nM
|
|
|
|
CP0466709
|
US8846929, 123
Show/Hide
|
C30H37N5O3
|
1
|
| 1 |
Ki = 13745 nM
|
|
|
|
CP0383583
|
US8846929, 101
Show/Hide
|
C27H39N5O
|
1
|
| 1 |
Ki = 13970 nM
|
|
|
|
CP0529289
|
US8846929, 312
Show/Hide
|
C27H36N4O4
|
1
|
| 1 |
Ki = 14500 nM
|
|
|
|
CP0529290
|
US8846929, 320
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
Ki = 15010 nM
|
|
|
|
CP0442031
|
US8846929, 14
Show/Hide
|
C26H38N4O3
|
1
|
| 1 |
Ki = 15188 nM
|
|
|
|
CP0490203
|
US9290488, K2b(ii)
Show/Hide
|
C29H38N4O3
|
1
|
| 1 |
Ki = 15400 nM
|
|
|
|
CP0503750
|
US8846929, 88
Show/Hide
|
C22H28N4O
|
1
|
| 1 |
Ki = 15584 nM
|
|
|
|
CP0510253
|
US8846929, 82
Show/Hide
|
C27H33N5O3
|
1
|
| 1 |
Ki = 15770 nM
|
|
|
|
CP0472344
|
US8637502, 5
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 16200 nM
|
|
|
|
CP0478853
|
US9090618, H30b(i)
Show/Hide
|
C31H44N4O2
|
1
|
| 1 |
Ki = 16200 nM
|
|
|
|
CP0443113
|
US8846929, 188
Show/Hide
|
C29H40N4O4
|
1
|
| 1 |
Ki = 16400 nM
|
|
|
|
CP0491110
|
US8846929, 78
Show/Hide
|
C23H32N4O2
|
1
|
| 1 |
Ki = 16831 nM
|
|
|
|
CP0899416
|
US8846929, 122
Show/Hide
|
C29H35N5O3
|
1
|
| 1 |
Ki = 17516 nM
|
|
|
|
CP0472349
|
US8846929, 128
Show/Hide
|
C27H36N4O4
|
1
|
| 1 |
Ki = 17638 nM
|
|
|
|
CP0510254
|
US8846929, 85
Show/Hide
|
C21H31N3O
|
1
|
| 1 |
Ki = 17850 nM
|
|
|
|
CP0223449
|
US8846929, 356
Show/Hide
|
C28H39N3O3
|
1
|
| 1 |
Ki = 18180 nM
|
|
|
|
CP0503751
|
US8846929, 328
Show/Hide
|
C31H45N5O3
|
1
|
| 1 |
Ki = 18818 nM
|
|
|
|
CP0512244
|
US8846929, 56
Show/Hide
|
C24H34N4O4
|
1
|
| 1 |
Ki = 19145 nM
|
|
|
|
CP0531762
|
US8846929, 22
Show/Hide
|
C26H39N5O
|
1
|
| 1 |
Ki = 19407 nM
|
|
|
|
CP0529286
|
US8846929, 7
Show/Hide
|
C28H43N5O3
|
1
|
| 1 |
Ki = 19610 nM
|
|
|
|
CP0406798
|
US9090618, H58d(ii)
Show/Hide
|
C33H48N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0412095
|
US9090618, B56c(ii)
Show/Hide
|
C31H44N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0412097
|
US9090618, ZA48
Show/Hide
|
C33H48N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0413164
|
US9090618, H36b(i)
Show/Hide
|
C31H45N5O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0413165
|
US9090618, ZA52
Show/Hide
|
C36H55N5O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0426226
|
US9090618, ZA10
Show/Hide
|
C34H50N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0426229
|
US9090618, ZA50
Show/Hide
|
C33H51N5O2S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0442552
|
US9090618, ZA43
Show/Hide
|
C33H51N5O2S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0450742
|
US9090618, ZA35
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0479194
|
US9090618, H32b(ii)
Show/Hide
|
C32H46N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0500380
|
US9090618, H56d(ii)
Show/Hide
|
C32H46N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0526549
|
US9090618, ZA56
Show/Hide
|
C30H44N4O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0529180
|
US9090618, ZA55
Show/Hide
|
C30H44N4O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0538970
|
US9090618, ZA58
Show/Hide
|
C33H48N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0550113
|
US9090618, ZA59
Show/Hide
|
C33H48N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0556385
|
US9090618, H56b(ii)
Show/Hide
|
C32H46N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0957292
|
US9090618, ZA68
Show/Hide
|
C28H37N5
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0412571
|
US8846929, 228
Show/Hide
|
C29H41N5O5
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0413138
|
US8846929, 211
Show/Hide
|
C31H45N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0417247
|
US8846929, 194
Show/Hide
|
C31H43N5O4
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0443713
|
US8846929, 326
Show/Hide
|
C35H51N5O5
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0450106
|
US8846929, 193
Show/Hide
|
C29H41N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0450786
|
US8846929, 355
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0466577
|
US8846929, 207
Show/Hide
|
C31H38N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0470333
|
US8846929, 235
Show/Hide
|
C23H31N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0470951
|
US8846929, 197
Show/Hide
|
C27H38N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0470952
|
US8846929, 216
Show/Hide
|
C31H43N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0483217
|
US8846929, 279
Show/Hide
|
C28H39N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0491118
|
US8846929, 323
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0492151
|
US8846929, 203
Show/Hide
|
C30H41N5O4
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0510247
|
US8846929, 335
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0515133
|
US8846929, 305
Show/Hide
|
C31H38N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0531764
|
US8846929, 327
Show/Hide
|
C31H43N5O5
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0533591
|
US8846929, 286
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0535561
|
US8846929, 174
Show/Hide
|
C29H39N5O4
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0545697
|
US8846929, 199
Show/Hide
|
C30H42N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0545896
|
US8846929, 270
Show/Hide
|
C28H25N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0554241
|
US8846929, 288
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0556940
|
US8846929, 221
Show/Hide
|
C29H42N6O4
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0557345
|
US8846929, 178
Show/Hide
|
C28H39N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0558717
|
US8846929, 218
Show/Hide
|
C28H41N5O4
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0561856
|
US8846929, 212
Show/Hide
|
C27H37N5O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0941773
|
US8846929, 317
Show/Hide
|
C26H34N8O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0129542
|
US8476271, 97
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0413438
|
US9145408, 360
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0478850
|
US9145408, 369
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0451938
|
US9290488, ZA04
Show/Hide
|
C30H41N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0516743
|
US9290488, ZA05
Show/Hide
|
C32H45N5O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0544986
|
US9290488, B2a(ii)
Show/Hide
|
C29H38N4O3
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0484468
|
US8846929, 81
Show/Hide
|
C24H34N4O2
|
1
|
| 1 |
Ki = 20507 nM
|
|
|
|
CP0524499
|
US8637502, 56
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
Ki = 20800 nM
|
|
|
|
CP0510252
|
US8846929, 79
Show/Hide
|
C25H36N4O4
|
1
|
| 1 |
Ki = 20971 nM
|
|
|
|
CP0503749
|
US8846929, 77
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki = 21144 nM
|
|
|
|
CP0551328
|
US8637502, 57
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
Ki = 21900 nM
|
|
|
|
CP0399425
|
US8846929, 306
Show/Hide
|
C29H38N4O4
|
1
|
| 1 |
Ki = 22330 nM
|
|
|
|
CP0442032
|
US8846929, 21
Show/Hide
|
C31H47N5O3
|
1
|
| 1 |
Ki = 22592 nM
|
|
|
|
CP0450748
|
US8637502, 61
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 22800 nM
|
|
|
|
CP0491116
|
US8846929, 307
Show/Hide
|
C27H36N4O4
|
1
|
| 1 |
Ki = 23090 nM
|
|
|
|
CP0520563
|
US8846929, 5
Show/Hide
|
C27H39N5O
|
1
|
| 1 |
Ki = 23220 nM
|
|
|
|
CP0526528
|
US8637502, 60
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 23400 nM
|
|
|
|
CP0529284
|
US8846929, 80
Show/Hide
|
C28H35N5O3
|
1
|
| 1 |
Ki = 23741 nM
|
|
|
|
CP0464915
|
US8846929, 114
Show/Hide
|
C29H40N4O3
|
1
|
| 1 |
Ki = 24072 nM
|
|
|
|
CP0503753
|
US8846929, 15
Show/Hide
|
C21H30N4O
|
1
|
| 1 |
Ki = 24560 nM
|
|
|
|
CP0442039
|
US8846929, 133
Show/Hide
|
C24H30FN3O3
|
1
|
| 1 |
Ki = 25020 nM
|
|
|
|
CP0412569
|
US8846929, 126
Show/Hide
|
C27H40N4O4
|
1
|
| 1 |
Ki = 25970 nM
|
|
|
|
CP0466574
|
US8846929, 129
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
Ki = 26095 nM
|
|
|
|
CP0442188
|
US8846929, 34
Show/Hide
|
C27H35N5O2
|
1
|
| 1 |
Ki = 26105 nM
|
|
|
|
CP0450783
|
US8846929, 103
Show/Hide
|
C25H35N5O2
|
1
|
| 1 |
Ki = 26460 nM
|
|
|
|
CP0529287
|
US8846929, 10
Show/Hide
|
C25H37N5O
|
1
|
| 1 |
Ki = 27675 nM
|
|
|
|
CP0450788
|
US8846929, 27
Show/Hide
|
C27H38N4O3
|
1
|
| 1 |
Ki = 27790 nM
|
|
|
|
CP0442030
|
US8846929, 2
Show/Hide
|
C23H34N4O
|
1
|
| 1 |
Ki = 28064 nM
|
|
|
|
CP0503755
|
US8846929, 51
Show/Hide
|
C25H37N5O
|
1
|
| 1 |
Ki = 28106 nM
|
|
|
|
CP0484465
|
US8846929, 61
Show/Hide
|
C26H38N4O3
|
1
|
| 1 |
Ki = 28131 nM
|
|
|
|
CP0553793
|
US8846929, 66
Show/Hide
|
C26H39N5O3S
|
1
|
| 1 |
Ki = 28211 nM
|
|
|
|
CP0515132
|
US8846929, 87
Show/Hide
|
C26H38N6O
|
1
|
| 1 |
Ki = 29200 nM
|
|
|
|
CP0383584
|
US8846929, 104
Show/Hide
|
C26H37N5O3
|
1
|
| 1 |
Ki = 29775 nM
|
|
|
|
CP0919309
|
US8846929, 71
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
Ki = 31727 nM
|
|
|
|
CP0545906
|
US8846929, 282
Show/Hide
|
C29H35N5O3
|
1
|
| 1 |
Ki = 32209 nM
|
|
|
|
CP0503754
|
US8846929, 16
Show/Hide
|
C28H40N4O3
|
1
|
| 1 |
Ki = 34024 nM
|
|
|
|
CP0520566
|
US8846929, 31
Show/Hide
|
C26H39N5O
|
1
|
| 1 |
Ki = 34671 nM
|
|
|
|
CP0443711
|
US8846929, 92
Show/Hide
|
C25H36N4O2
|
1
|
| 1 |
Ki = 34954 nM
|
|
|
|
CP0466710
|
US8846929, 111
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 35615 nM
|
|
|
|
CP0443703
|
US8846929, 26
Show/Hide
|
C24H37N7O
|
1
|
| 1 |
Ki = 35858 nM
|
|
|
|
CP0464045
|
US8846929, 191
Show/Hide
|
C27H37N5O4
|
1
|
| 1 |
Ki = 37410 nM
|
|
|
|
CP0491121
|
US8846929, 17
Show/Hide
|
C23H32N4O2
|
1
|
| 1 |
Ki = 37800 nM
|
|
|
|
CP0519156
|
US8846929, 90
Show/Hide
|
C25H35N5O2
|
1
|
| 1 |
Ki = 38310 nM
|
|
|
|
CP0441924
|
US8846929, 60
Show/Hide
|
C27H39N5O2
|
1
|
| 1 |
Ki = 38477 nM
|
|
|
|
CP0450790
|
US8846929, 43
Show/Hide
|
C30H38N4O
|
1
|
| 1 |
Ki = 38851 nM
|
|
|
|
CP0399072
|
US8846929, 240
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 41190 nM
|
|
|
|
CP0402596
|
US8846929, 125
Show/Hide
|
C27H38N4O4
|
1
|
| 1 |
Ki = 42000 nM
|
|
|
|
CP0542020
|
US8846929, 52
Show/Hide
|
C26H38N4O2
|
1
|
| 1 |
Ki = 43207 nM
|
|
|
|
CP0529282
|
US8846929, 13
Show/Hide
|
C29H41N5O2
|
1
|
| 1 |
Ki = 43483 nM
|
|
|
|
CP0399432
|
US8846929, 11
Show/Hide
|
C24H37N5O3S
|
1
|
| 1 |
Ki = 44071 nM
|
|
|
|
CP0503746
|
US8846929, 44
Show/Hide
|
C32H40N4O3
|
1
|
| 1 |
Ki = 45038 nM
|
|
|
|
CP0491125
|
US8846929, 58
Show/Hide
|
C24H37N5O2
|
1
|
| 1 |
Ki = 45883 nM
|
|
|
|
CP0450781
|
US8846929, 45
Show/Hide
|
C26H33N5O2
|
1
|
| 1 |
Ki = 46719 nM
|
|
|
|
CP0484463
|
US8846929, 9
Show/Hide
|
C23H35N5O
|
1
|
| 1 |
Ki = 47271 nM
|
|
|
|
CP0520571
|
US8846929, 243
Show/Hide
|
C24H31N3O3
|
1
|
| 1 |
Ki = 47391 nM
|
|
|
|
CP0503757
|
US8846929, 102
Show/Hide
|
C26H38N4O3
|
1
|
| 1 |
Ki = 49120 nM
|
|
|
|
CP0450777
|
US8846929, 23
Show/Hide
|
C28H41N5O2
|
1
|
| 1 |
Ki = 52099 nM
|
|
|
|
CP0550161
|
US8637502, 47
Show/Hide
|
C25H36N4O3
|
1
|
| 1 |
Ki = 52100 nM
|
|
|
|
CP0529283
|
US8846929, 39
Show/Hide
|
C25H37N5O
|
1
|
| 1 |
Ki = 52574 nM
|
|
|
|
CP0519154
|
US8846929, 59
Show/Hide
|
C27H39N5O2
|
1
|
| 1 |
Ki = 53164 nM
|
|
|
|
CP0491128
|
US8846929, 95
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
Ki = 53540 nM
|
|
|
|
CP0517946
|
US8637502, 66
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
Ki = 54760 nM
|
|
|
|
CP0442025
|
US8846929, 68
Show/Hide
|
C25H36N4O2
|
1
|
| 1 |
Ki = 54999 nM
|
|
|
|
CP0450787
|
US8846929, 18
Show/Hide
|
C25H35N5O2
|
1
|
| 1 |
Ki = 55229 nM
|
|
|
|
CP0442024
|
US8846929, 37
Show/Hide
|
C27H39N5O2
|
1
|
| 1 |
Ki = 56989 nM
|
|
|
|
CP0466711
|
BDBM12181
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 57741 nM
|
|
|
|
CP0491124
|
US8846929, 50
Show/Hide
|
C27H41N5O3S
|
1
|
| 1 |
Ki = 59230 nM
|
|
|
|
CP0442033
|
US8846929, 24
Show/Hide
|
C24H34N4O
|
1
|
| 1 |
Ki = 60848 nM
|
|
|
|
CP0520565
|
US8846929, 30
Show/Hide
|
C27H41N5O3S
|
1
|
| 1 |
Ki = 61698 nM
|
|
|
|
CP0551327
|
US8637502, 44
Show/Hide
|
C23H30N4O2
|
1
|
| 1 |
Ki = 65660 nM
|
|
|
|
CP0510248
|
US8846929, 28
Show/Hide
|
C27H38N4O4
|
1
|
| 1 |
Ki = 66315 nM
|
|
|
|
CP0491130
|
US8846929, 329
Show/Hide
|
C35H51N5O5
|
1
|
| 1 |
Ki = 67102 nM
|
|
|
|
CP0470331
|
US8846929, 253
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 68750 nM
|
|
|
|
CP0517899
|
US8637502, 67
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 72400 nM
|
|
|
|
CP0545907
|
US8846929, 284
Show/Hide
|
C29H41N5O3
|
1
|
| 1 |
Ki = 72511 nM
|
|
|
|
CP0546869
|
(2S)-1-{[(2S,5S)-5-(hydroxymethyl)pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carbonitrile
Show/Hide
|
C11H17N3O2
|
1
|
| 1 |
Ki = 76337 nM
|
|
|
|
CP0491123
|
US8846929, 42
Show/Hide
|
C26H37N5O2
|
1
|
| 1 |
Ki = 81321 nM
|
|
|
|
CP0442187
|
US8846929, 25
Show/Hide
|
C24H36N4O3
|
1
|
| 1 |
Ki = 82251 nM
|
|
|
|
CP0503748
|
US8846929, 65
Show/Hide
|
C25H38N4O3
|
1
|
| 1 |
Ki = 85587 nM
|
|
|
|
CP0484466
|
US8846929, 67
Show/Hide
|
C24H36N4O3
|
1
|
| 1 |
Ki = 86219 nM
|
|
|
|
CP0520567
|
US8846929, 33
Show/Hide
|
C24H35N5O3
|
1
|
| 1 |
Ki = 96003 nM
|
|
|
|
CP0402598
|
US8846929, 226
Show/Hide
|
C27H39N5O3
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0450102
|
US8846929, 119
Show/Hide
|
C24H33N5O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0450773
|
US8846929, 3
Show/Hide
|
C23H34N4O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0464036
|
US8846929, 124
Show/Hide
|
C29H35N5O3
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0464918
|
US8846929, 127
Show/Hide
|
C24H32N4O3
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0557306
|
US8846929, 47
Show/Hide
|
C24H35N5O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0377807
|
(1-{4-[2-(3,3-Dimethylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C27H43N5O
|
1
|
| 1 |
Ki > 500 nM
|
|
|
|
CP0377808
|
(1-{4-[2-(3-Methylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C26H41N5O
|
1
|
| 1 |
Ki > 500 nM
|
|
|
|
CP0038350
|
(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanamido]-5-carbamimidamidopentanamido]hexanamido]-3-hydroxypropanamido]propanamido]-5-carbamimidamidopentanamido]hexanamido]-4-methylpentanamido]propanamido]butanediamido]-4-carbamoylbutanoic acid
Show/Hide
|
C79H129N27O22
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0372512
|
(+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
|
C21H27Cl2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0372529
|
(+)-1-{(1S,2S,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
|
C22H29Cl2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373152
|
(+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
|
C22H29Cl2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0390914
|
(1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
|
C21H27Cl2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0390917
|
(-)-1-{(1R,2R,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
|
C22H29Cl2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0390918
|
(+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C26H31Cl2N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0390920
|
(-)-1-{(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
|
C22H29Cl2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0390922
|
(-)-Methyl(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
|
C21H27Cl2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0417979
|
(+)-1-[(1S,2S,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C26H31Cl2N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0417987
|
(-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C26H31Cl2N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0475786
|
(-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo-[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C26H31Cl2N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479308
|
(1S,2S,5R)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
|
C21H27Cl2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0145209
|
[1-[4-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctyl]methanol
Show/Hide
|
C27H41N5O
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0427455
|
1-{1-[1-(Hydroxymethyl)cyclooctyl]piperidin-4-yl}-1Hbenzimidazol-2(3H)-one
Show/Hide
|
C21H31N3O2
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
