Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
 Cell Line Info 
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01172 , Progesterone receptor
 Protein Info 
Gene Name PGR
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P06401
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026
 Cell Line Info 
 Protein ID: PT01172
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0035186
 Compound Info 
(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
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C29H35NO2
  1
1
IC50 = 0.4 nM
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CP0412317
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C32H43NO2
  1
1
IC50 = 3.4 nM
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CP0438095
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-11-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C35H48N2O4S
  1
1
IC50 = 4.6 nM
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CP0396796
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-11-(4-morpholin-4-ylphenyl)-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C34H45NO3
  1
1
IC50 = 4.8 nM
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CP0396797
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-11-[4-(diethylamino)phenyl]-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C34H47NO2
  1
1
IC50 = 6 nM
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CP0434728
 Compound Info 
(8S,9S,10R,11S,13S,14S,17S)-11-[(4-chlorophenyl)methoxy]-17-hydroxy-10,13-dimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C29H35ClO3
  1
1
IC50 = 8.2 nM
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CP0343817
 Compound Info 
(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
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C32H41NO2
  1
1
IC50 = 14.4 nM
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CP0068675
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-11-[4-[methyl(propan-2-yl)amino]phenyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C34H47NO2
  1
1
IC50 = 21 nM
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CP0396799
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylpent-1-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C33H45NO2
  1
1
IC50 = 21.1 nM
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CP0529952
 Compound Info 
(8R,9S,10R,11S,13S,14S,17S)-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-13-methyl-11-[4-(4-methylpiperazin-1-yl)phenyl]-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
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C35H48N2O2
  1
1
IC50 = 25.4 nM
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CP0529951
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-17-prop-1-ynyl-11-(4-pyrrol-1-ylphenyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H37NO2
  1
1
IC50 = 523 nM
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CP0485770
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-11-[4-[methyl(propan-2-yl)amino]phenyl]-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H43NO2
  1
1
IC50 = 527 nM
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CP0531036
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-10,13-dimethyl-17-(3,3,3-trifluoroprop-1-ynyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C30H36F3NO2
  1
1
IC50 = 910 nM
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CP0421754
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-10,13-dimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C30H39NO2
  1
1
IC50 = 1135 nM
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CP0343816
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-(2-cyclopropylethynyl)-11-[4-(dimethylamino)phenyl]-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H41NO2
  1
1
IC50 = 1487 nM
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CP0434729
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-but-1-ynyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C31H41NO2
  1
1
IC50 = 1546 nM
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CP0438094
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-hydroxy-11-[4-[2-methoxyethyl(methyl)amino]phenyl]-10,13-dimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H43NO3
  1
1
IC50 = 1640 nM
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CP0470985
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-hydroxy-11-(4-methoxyphenyl)-10,13-dimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C29H36O3
  1
1
IC50 = 1689 nM
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CP0396800
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-10,13-dimethyl-17-(3-methylbut-1-ynyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H43NO2
  1
1
IC50 = 2084 nM
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CP0421753
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-ynyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C33H45NO2
  1
1
IC50 = 2488 nM
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CP0471010
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-17-prop-1-ynyl-11-(4-pyrrolidin-1-ylphenyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C32H41NO2
  1
1
IC50 = 4068 nM
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CP0407827
 Compound Info 
(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carbonitrile
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C21H20N4O2
  1
1
IC50 = 4200 nM
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CP0527812
 Compound Info 
(8S,9R,10R,11S,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(3-methoxyprop-1-ynyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
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C31H41NO3
  1
1
IC50 = 4242 nM
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CP0460490
 Compound Info 
(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2-methyl-1,4-dihydro-1,6-naphthyridine-3-carbonitrile
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C20H18N4O2
  1
1
IC50 = 5400 nM
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CP0723935
 Compound Info 
(S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
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C21H22N4O3
  1
1
IC50 >= 10000 nM
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