| Compound ID |
Compound Name |
Compound Formula |
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CP0000753
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C88H137N17O18
|
2
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| 1 |
EC50 > 30000 nM
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|
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| 2 |
IC50 > 30000 nM
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CP0082953
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2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride
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|
C19H23NO5
|
1
|
| 1 |
IC50 = 1 nM
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|
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CP0402722
|
5,6-dimethyl-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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C21H27F3N4O3
|
1
|
| 1 |
Ki = 0.03981 nM
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|
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CP0453534
|
3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-quinazoline-2,4-dione
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|
C23H25F3N4O3
|
1
|
| 1 |
Ki = 0.0631 nM
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|
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CP0372270
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3-[4-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]butyl]-5-methyl-1H-pyrimidine-2,4-dione
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C21H26F4N4O3
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
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CP0049375
|
5-Methyl-3-(3-{4-[2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1H-pyrimidine-2,4-dione
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|
C20H25F3N4O3
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
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CP0404098
|
5-fluoro-3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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|
C19H21F5N4O3
|
1
|
| 1 |
Ki = 0.2512 nM
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|
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CP0494754
|
6-methyl-4-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-2H-1,2,4-triazine-3,5-dione
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|
C19H24F3N5O3
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
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CP0497518
|
3-[2-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]ethyl]-5-methyl-1H-pyrimidine-2,4-dione
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|
C19H22F4N4O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
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CP0469583
|
5-ethyl-3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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|
C21H26F4N4O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
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CP0497521
|
5-methyl-3-[[1-[[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]methyl]cyclopropyl]methyl]-1H-pyrimidine-2,4-dione
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|
C22H27F3N4O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
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CP0405701
|
3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1,3-diazinane-2,4-dione
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|
C19H24F4N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
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CP0453316
|
5-chloro-3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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|
C19H21ClF4N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
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CP0192450
|
3-(3-{3-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-5-methyl-1H-pyrimidine-2,4-dione
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|
C20H24F4N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
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CP0449087
|
3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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|
C19H22F4N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
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CP0404116
|
3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-methoxy-1H-pyrimidine-2,4-dione
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|
C20H24F4N4O4
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
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CP0442185
|
3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-6-methyl-1H-pyrimidine-2,4-dione
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|
C20H24F4N4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
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CP0498606
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5-methyl-1-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]pyrimidine-2,4-dione
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|
C20H25F3N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
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CP0505309
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3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-propan-2-yl-1H-pyrimidine-2,4-dione
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|
C22H28F4N4O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
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CP0453297
|
3-[2,2-dimethyl-3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-methyl-1H-pyrimidine-2,4-dione
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|
C22H29F3N4O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
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CP0404179
|
(5R,6S)-3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5,6-dihydroxy-5-methyl-1,3-diazinane-2,4-dione
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|
C20H26F4N4O5
|
1
|
| 1 |
Ki = 5.012 nM
|
|
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CP0432643
|
5-(dimethylamino)-3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione
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|
C21H27F4N5O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
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CP0442597
|
3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-(hydroxymethyl)-1H-pyrimidine-2,4-dione
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|
C20H24F4N4O4
|
1
|
| 1 |
Ki = 7.943 nM
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|
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CP0403994
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3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-(trifluoromethyl)-1H-pyrimidine-2,4-dione
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|
C20H22F6N4O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
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CP0429302
|
N-[2-(2-chloro-5-fluorophenoxy)ethyl]-3-(2-methylsulfonylphenyl)propan-1-amine
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|
C18H21ClFNO3S
|
1
|
| 1 |
Ki = 50 nM
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CP0414929
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(4S)-4-N-[2-(2,5-difluorophenoxy)ethyl]-6-N-methyl-1,1-dioxo-3,4-dihydro-2H-thiochromene-4,6-diamine;hydrochloride
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|
C18H21ClF2N2O3S
|
1
|
| 1 |
Ki = 130 nM
|
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CP0532153
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N-[2-(2-chloro-5-fluorophenoxy)ethyl]-2-(2-methylsulfonylphenyl)ethanamine
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|
C17H19ClFNO3S
|
1
|
| 1 |
Ki = 150 nM
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CP0873943
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5-chloro-1-(5-chloro-2-(methylthio)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrochloride
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|
C14H14Cl3N3OS
|
1
|
| 1 |
Ki = 220 nM
|
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CP0414930
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4-N-[2-(2,5-difluorophenoxy)ethyl]-6-N-methyl-1,1-dioxo-3,4-dihydro-2H-thiochromene-4,6-diamine;hydrochloride
Show/Hide
|
C18H21ClF2N2O3S
|
1
|
| 1 |
Ki = 350 nM
|
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CP0450836
|
(4R)-4-N-[2-(2,5-difluorophenoxy)ethyl]-6-N-methyl-1,1-dioxo-3,4-dihydro-2H-thiochromene-4,6-diamine;hydrochloride
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|
C18H21ClF2N2O3S
|
1
|
| 1 |
Ki = 1200 nM
|
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CP0893288
|
2-(2-Chloro-5-fluorophenoxy)-N-[5-chloro-2-(methylsulfonyl)benzyl]ethanamine hydrochloride
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|
C16H17Cl3FNO3S
|
1
|
| 1 |
Ki = 1800 nM
|
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CP0445906
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N-[2-(2-chloro-5-fluorophenoxy)ethyl]-1,1-dioxo-3,4-dihydro-2H-thiochromen-4-amine;hydrochloride
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|
C17H18Cl2FNO3S
|
1
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| 1 |
Ki > 270 nM
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CP0450835
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N-[2-(2-chloro-5-fluorophenoxy)ethyl]-1-(2-methylsulfonylphenyl)ethanamine;hydrochloride
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|
C17H20Cl2FNO3S
|
1
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| 1 |
Ki > 270 nM
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CP0547513
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N-[2-(2-chloro-5-fluorophenoxy)ethyl]-1,1-dioxo-2,3-dihydro-1-benzothiophen-3-amine;hydrochloride
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|
C16H16Cl2FNO3S
|
1
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| 1 |
Ki > 270 nM
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CP0866794
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N-(3-Chlorobenzyl)-2-(2-chloro-5-fluorophenoxy)ethanamine hydrochloride
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|
C15H15Cl3FNO
|
1
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| 1 |
Ki > 270 nM
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CP0867038
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2-(2-Chloro-5-fluorophenoxy)-N-[2-(methylsulfonyl)benzyl]ethanamine hydrochloride
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C16H18Cl2FNO3S
|
1
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| 1 |
Ki > 270 nM
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CP0240279
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1-benzyl-5-chloro-2-iminopyridine-3-carboxamide
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|
C13H12ClN3O
|
1
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| 1 |
Ki > 2700 nM
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