Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01026 , Sodium-dependent noradrenaline transporter
Gene Name SLC6A2
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P23975
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01026
 
Compound ID Compound Name Compound Formula
CP0779578
N-(((6S,7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl)methyl)acetamide hemi fumarate
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C18H22Cl2N2O6
 1
1
IC50 = 0.33 nM
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CP0500782
N-[[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl]acetamide;hydrochloride
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C14H19Cl3N2O2
 1
1
IC50 = 0.33 nM
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CP0882725
(6R,7R)-7-(3,4-Dichlorophenyl)-N,N-dimethyl-1,4-oxazepane-6-carboxamide monohydrochloride
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C14H19Cl3N2O2
 1
1
IC50 = 0.77 nM
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CP0500787
N-[[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl]-2-methoxyacetamide;hydrochloride
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C15H21Cl3N2O3
 1
1
IC50 = 1.2 nM
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CP0444775
N-[[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl]propanamide;hydrochloride
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C15H21Cl3N2O2
 1
1
IC50 = 1.5 nM
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CP0444767
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]benzamide;hydrochloride
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C19H21Cl2FN2O2
 1
1
IC50 = 1.7 nM
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CP0917019
((6S,7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl)methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 2 nM
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CP0807335
Rac-(4-(3,4-Dichlorophenyl)azepan-4-yl)methanol monohydrochloride
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C13H18Cl3NO
 1
1
IC50 = 2.1 nM
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CP0873467
N-(((6S,7R)-7-(4-Chloro-3-fluorophenyl)-1,4-oxazepan-6-yl)methyl)acetamide monohydrochloride
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C14H19Cl2FN2O2
 1
1
IC50 = 2.3 nM
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CP0478033
N-[[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl]butanamide;hydrochloride
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C16H23Cl3N2O2
 1
1
IC50 = 2.6 nM
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CP0500780
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-1,4-dioxane-2-carboxamide;hydrochloride
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C17H23Cl2FN2O4
 1
1
IC50 = 2.6 nM
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CP0549462
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-methoxyacetamide;hydrochloride
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C15H21Cl2FN2O3
 1
1
IC50 = 3.2 nM
   TI
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CP0927979
N-(((6S,7R)-7-(4-Chloro-3-methylphenyl)-1,4-oxazepan-6-yl)methyl)acetamide monohydrochloride
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C15H22Cl2N2O2
 1
1
IC50 = 3.3 nM
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CP0444770
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-ethoxyacetamide;hydrochloride
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C16H23Cl2FN2O3
 1
1
IC50 = 3.3 nM
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CP0500784
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-(trideuteriomethoxy)acetamide;hydrochloride
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C15H21Cl2FN2O3
 1
1
IC50 = 3.3 nM
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CP0910706
N-(((6S,7R)-7-(3-Chloro-4-methylphenyl)-1,4-oxazepan-6-yl)methyl)acetamide monohydrochloride
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C15H22Cl2N2O2
 1
1
IC50 = 3.4 nM
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CP0517159
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-3-methoxypropanamide;hydrochloride
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C16H23Cl2FN2O3
 1
1
IC50 = 3.9 nM
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CP0500785
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-propan-2-yloxyacetamide;hydrochloride
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C17H25Cl2FN2O3
 1
1
IC50 = 4.8 nM
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CP0500783
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]oxolane-2-carboxamide;hydrochloride
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C17H23Cl2FN2O3
 1
1
IC50 = 5.3 nM
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CP0875180
[(7S)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-7-yl]methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 5.6 nM
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CP0856844
N-(2-((6R,7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl)ethyl)acetamide monohydrochloride
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C15H21Cl3N2O2
 1
1
IC50 = 5.8 nM
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CP0927972
((6R,7S)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl)methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 5.8 nM
   TI
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CP0830796
[(6R,7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl]methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 6 nM
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CP0808632
[(6S,7S)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-6-yl]methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 8.5 nM
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CP0517160
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-methoxypropanamide;hydrochloride
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C16H23Cl2FN2O3
 1
1
IC50 = 8.8 nM
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CP0910705
(6R,7R)-7-(3,4-Dichlorophenyl)-N-methyl-1,4-oxazepane-6-carboxamide monohydrochloride
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C13H17Cl3N2O2
 1
1
IC50 = 12 nM
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CP0927974
N-(((6S,7R)-7-(3-Chloro-4-fluorophenyl)-1,4-oxazepan-6-yl)methyl)acetamide hemi fumarate
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C18H22ClFN2O6
 1
1
IC50 = 13 nM
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CP0704677
Rac-[7-(3,4-Dichlorophenyl)-1,4-oxazepan-7-yl]methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 17 nM
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CP0517156
N-[[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl]-2-methoxy-2-methylpropanamide;hydrochloride
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C17H25Cl2FN2O3
 1
1
IC50 = 21 nM
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CP0864592
(6R,7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepane-6-carboxamide monohydrochloride
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C12H15Cl3N2O2
 1
1
IC50 = 52 nM
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CP0719035
[(7R)-7-(3,4-Dichlorophenyl)-1,4-oxazepan-7-yl]methanol monohydrochloride
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C12H16Cl3NO2
 1
1
IC50 = 700 nM
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