| Compound ID |
Compound Name |
Compound Formula |
|
CP0529669
|
1-(6-thiophen-2-yl-pyridazin-3-yl)-piperidine-4-carboxylic acid [1-(4-methyl-benzyl)-pyrrolidin-3-ylmethyl]-amide
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|
C27H33N5OS
|
2
|
| 1 |
EC50 = 1100 nM
|
|
|
| 2 |
IC50 = 5800 nM
|
|
|
|
CP0383327
|
1-(3-diethylamino-propylamino)-3-methyl-2-(2-methyl-allyl)-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
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|
C24H31N5
|
2
|
| 1 |
EC50 = 1900 nM
|
|
|
| 2 |
IC50 = 22400 nM
|
|
|
|
CP0464262
|
N-[2-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-2-[(5-methyl-4-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
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|
C24H30N6OS
|
2
|
| 1 |
EC50 = 2000 nM
|
|
|
| 2 |
IC50 = 14100 nM
|
|
|
|
CP0433641
|
2-(4-benzyl-5-(2-(piperidin-1-yl)ethyl)-4H-1,2,4-triazol-3-ylthio)-N-(2,4-dimethylphenyl)acetamide
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|
C26H33N5OS
|
2
|
| 1 |
EC50 = 3000 nM
|
|
|
| 2 |
IC50 = 17000 nM
|
|
|
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CP0383328
|
N-(1-benzylpiperidin-4-yl)-2-[[5-methyl-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
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|
C24H29N5OS
|
1
|
| 1 |
EC50 = 13500 nM
|
|
|
|
CP0372025
|
1-((1-(4-fluorobenzyl)-1H-tetrazol-5-yl)(2-fluorophenyl)methyl)-4-cyclohexylpiperazine
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|
C25H30F2N6
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 79400 nM
|
|
|
|
CP0501987
|
3-(4-chlorophenyl)-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C29H37ClN6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0502073
|
3-(4-methylphenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C30H40N6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0405057
|
3-(3-chlorophenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C29H37ClN6O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0505135
|
1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1,3-diphenylurea
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|
C29H38N6O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0538622
|
3-(4-methoxyphenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C30H40N6O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0452798
|
3-(3-methylphenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C30H40N6O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0525658
|
3-cyclohexyl-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C29H44N6O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0462439
|
3-(2,3-dichlorophenyl)-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C29H36Cl2N6O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0505134
|
3-(3-methoxyphenyl)-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C30H40N6O2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0399608
|
3-cyclopentyl-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C28H42N6O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0462441
|
1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenyl-3-propan-2-ylurea
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|
C26H40N6O
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0525657
|
3-(2-chlorophenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C29H37ClN6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0462440
|
3-(2-methylphenyl)-1-[3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
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|
C30H40N6O
|
1
|
| 1 |
IC50 = 271 nM
|
|
|
|
CP0502074
|
1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenyl-3-propylurea
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|
C26H40N6O
|
1
|
| 1 |
IC50 = 271 nM
|
|
|
|
CP0490613
|
N-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-N-phenylcyclohexanecarboxamide
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|
C29H43N5O
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0530876
|
3-benzyl-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
Show/Hide
|
C30H40N6O
|
1
|
| 1 |
IC50 = 323 nM
|
|
|
|
CP0490612
|
3-(2-methoxyphenyl)-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
Show/Hide
|
C30H40N6O2
|
1
|
| 1 |
IC50 = 381 nM
|
|
|
|
CP0452797
|
3-(2,6-dichlorophenyl)-1-[3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-1-phenylurea
Show/Hide
|
C29H36Cl2N6O
|
1
|
| 1 |
IC50 = 539 nM
|
|
|
|
CP0396523
|
N-[1-[3-[1-(3,4-dichloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H33Cl2N5O3S
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0462438
|
N-[2-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-N-phenylcyclohexanecarboxamide
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|
C28H41N5O
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0518085
|
2-(4-oxo-3-(3-(piperidin-1-yl)propyl)-3,4-dihydroquinazolin-2-ylthio)-N-phenethylacetamide
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|
C26H32N4O2S
|
1
|
| 1 |
IC50 = 49000 nM
|
|
|
