| Compound ID |
Compound Name |
Compound Formula |
|
CP0579732
|
2-chloro-4-[[(2S)-2-cyclopropyl-3,3-difluoro-7-methyl-6-oxo-2,4-dihydro-1H-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C22H18ClF2N5O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0571635
|
2-chloro-4-[[(2R)-2-cyclopropyl-7-methyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C22H20ClN5O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0488441
|
2-chloro-4-[[1-methyl-2-oxo-4-(2-pyrimidin-2-ylpropan-2-ylamino)quinolin-6-yl]amino]pyridine-3-carbonitrile
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|
C23H20ClN7O
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0564296
|
US11161839, Example 10a
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|
C26H24ClN7O
|
1
|
| 1 |
IC50 = 570 nM
|
|
|
|
CP0564295
|
2-chloro-4-[(2-cyclopropyl-7-methyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl)amino]pyridine-3-carbonitrile
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|
C22H20ClN5O2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0579470
|
US11161839, Example 10f
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|
C23H20ClN7O
|
1
|
| 1 |
IC50 = 1080 nM
|
|
|
|
CP0545524
|
US11161839, Example 10e
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|
C25H22ClN7O
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0573712
|
US11161839, Example 1a
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|
C22H18ClN7O
|
1
|
| 1 |
IC50 = 1210 nM
|
|
|
|
CP0573586
|
US11161839, Example 11i
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|
C26H24ClN7O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0546969
|
2-chloro-4-[[(2S)-2,7-dimethyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C20H18ClN5O2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0546971
|
2-chloro-4-[[(2S,4S)-2,4,7-trimethyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0579603
|
2-chloro-4-[[(2S)-2-cyclopropyl-7-methyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C22H20ClN5O2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0578490
|
US11161839, Example 11h
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|
C25H22ClN7O
|
1
|
| 1 |
IC50 = 4780 nM
|
|
|
|
CP0579731
|
2-chloro-4-[[(2R)-2,7-dimethyl-6-oxo-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C20H18ClN5O2
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0578327
|
US20230287003, Example 1c
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|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0564297
|
US20230287003, Example 1h
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|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 6300 nM
|
|
|
|
CP0577049
|
US20230287003, Example 1i
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|
C22H20ClN5O2
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0546970
|
2-chloro-4-[[(2S)-2,7-dimethyl-5,6-dioxo-2,3-dihydro-1H-[1,4]oxazepino[6,5-c]quinolin-10-yl]amino]pyridine-3-carbonitrile
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|
C20H16ClN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
