Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT02406 , Histamine H2 receptor
 Protein Info 
Gene Name HRH2
Organism Cavia porcellus, Guinea pig
Protein Classification Membrane receptor
Uniprot ID P47747
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT02406
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0543300
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
   Show/Hide
C18H21F6N7O5S
  1
1
EC50 = 2.188 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546844
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-hexylurea;2,2,2-trifluoroacetic acid
   Show/Hide
C17H27F6N7O5S
  1
1
EC50 = 2.291 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0551746
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
   Show/Hide
C16H25F6N7O5S
  1
1
EC50 = 4.365 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543298
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[1-(3-fluorophenyl)ethyl]urea;dihydrochloride
   Show/Hide
C15H22Cl2FN7OS
  1
1
EC50 = 6.918 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546843
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[2-methyl-3-(4-methylphenyl)propyl]urea;2,2,2-trifluoroacetic acid
   Show/Hide
C22H29F6N7O5S
  1
1
EC50 = 14.79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543296
 Compound Info 
1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
   Show/Hide
C15H23Cl2N7O
  1
1
EC50 = 16.22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550064
 Compound Info 
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[(1R)-1-phenylethyl]urea;dihydrochloride
   Show/Hide
C15H23Cl2N7OS
  1
1
EC50 = 25.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036920
 Compound Info 
2-(1H-imidazol-4-yl)ethan-1-amine
   Show/Hide
C5H9N3
  1
1
EC50 = 251.19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS