Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT02327 , Peripheral plasma membrane protein CASK
 Protein Info 
Gene Name CASK
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O14936
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT02327
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0313025
 Compound Info 
4-(cyclopentylamino)-2-[(2,5-dibromo-4-methylphenyl)methylamino]-N-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C24H30Br2N6O3
  2
1
IC50 = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0130748
 Compound Info 
4-(cyclohexylamino)-2-[(2,5-dibromo-4-methylphenyl)methylamino]-N-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C25H32Br2N6O3
  2
1
IC50 = 106 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0018808
 Compound Info 
4-(cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-N-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C23H28Cl2N6O3
  2
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0559075
 Compound Info 
4-(cyclopentylamino)-2-[(2,4-dichlorophenyl)methylamino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C24H30Cl2N6O2
  1
1
IC50 = 1930 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0534020
 Compound Info 
2-[(4-chlorophenyl)methyl-ethylamino]-4-(cyclopentylamino)-N-[3-(2-oxopyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C26H35ClN6O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553239
 Compound Info 
2-[benzyl(ethyl)amino]-4-(cyclopentylamino)-N-[3-(2-oxopyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide
   Show/Hide
C26H36N6O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS