| Compound ID |
Compound Name |
Compound Formula |
|
CP0153943
|
4-[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-oxo-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0126332
|
6-(4-fluorophenyl)-2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H25FN2O
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0489290
|
4-[1-oxo-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C22H23N3O
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0127626
|
2-[2-(azepan-1-yl)ethyl]-6-(4-fluorophenyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C23H27FN2O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0417465
|
4-[2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-1-oxo-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0416903
|
3-[1-oxo-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C22H23N3O
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0416900
|
6-(3,4-difluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H22F2N2O
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0432179
|
6-(4-fluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0475883
|
2-(2-pyrrolidin-1-ylethyl)-6-[4-(trifluoromethyl)phenyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H23F3N2O
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0424649
|
6-(4-fluorophenyl)-2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H25FN2O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0416905
|
6-phenyl-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0416901
|
6-(3,5-difluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H22F2N2O
|
1
|
| 1 |
Ki = 146 nM
|
|
|
|
CP0461694
|
6-(2,4-difluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H22F2N2O
|
1
|
| 1 |
Ki = 153 nM
|
|
|
|
CP0498272
|
4-[1-oxo-2-(3-piperidin-1-ylpropyl)-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
Ki = 153 nM
|
|
|
|
CP0461680
|
6-(3-fluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 164 nM
|
|
|
|
CP0416916
|
6-(benzimidazol-1-yl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
Ki = 174 nM
|
|
|
|
CP0417464
|
6-(2-fluorophenyl)-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 174 nM
|
|
|
|
CP0462621
|
2-(2-pyrrolidin-1-ylethyl)-6-[4-(trifluoromethoxy)phenyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H23F3N2O2
|
1
|
| 1 |
Ki = 178 nM
|
|
|
|
CP0566427
|
2-(2-pyrrolidin-1-ylethyl)-6-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H23F3N2O
|
1
|
| 1 |
Ki = 182 nM
|
|
|
|
CP0432180
|
4-[1-oxo-2-(3-pyrrolidin-1-ylpropyl)-3,4-dihydroisoquinolin-6-yl]benzonitrile
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0416904
|
2-(2-pyrrolidin-1-ylethyl)-6-[3-(trifluoromethoxy)phenyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C22H23F3N2O2
|
1
|
| 1 |
Ki = 276 nM
|
|
|
