Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT01151 , Amyloid-beta precursor protein
 Protein Info 
Gene Name APP
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P05067
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT01151
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0375976
 Compound Info 
3-N-[(2S,3S,5R)-3-amino-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C39H53N5O4
  1
1
IC50 = 5.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393978
 Compound Info 
3-N-[(2S,3S,5R)-3-amino-5-[(4-fluorophenyl)carbamoyl]-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C33H41FN4O3
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0375975
 Compound Info 
3-N-[(1R,3S,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H55N5O4
  1
1
IC50 = 740 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0505665
 Compound Info 
3-N-[(1R,3S,4S)-3-amino-1-[(4-fluorophenyl)carbamoyl]-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C30H43FN4O3
  1
1
IC50 = 6000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419596
 Compound Info 
3-N-[(1R,3R,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H55N5O4
  1
1
IC50 = 9900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393976
 Compound Info 
3-N-[(1R,3S,4S)-1-[(4-fluorophenyl)carbamoyl]-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C30H42FN3O4
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381466
 Compound Info 
3-N-[(1R,3S,4S)-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H54N4O5
  1
1
IC50 > 6700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS