Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT01056 , Dual specificity tyrosine-phosphorylation-regulated kinase 1B
Gene Name DYRK1B
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9Y463
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025  Protein ID: PT01056
 
Compound ID Compound Name Compound Formula
CP0073979
N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
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C24H27N7O
 1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
CP0546860
4-[5-[(2-aminophenyl)methylcarbamoyl]thiophen-2-yl]-5-chloro-1-benzothiophene-2-carboxamide
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C21H16ClN3O2S2
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0546502
4-[5-[(2-aminophenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
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C21H17N3O2S2
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0835393
CmpdA
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C20H14ClN3O2S2
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0567741
4-[5-[(2-hydroxyphenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
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C21H16N2O3S2
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0550092
4-[5-[(4-aminophenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
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C21H17N3O2S2
 1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0569737
4-[5-(benzylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide
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C21H16N2O2S2
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS