Brief Information of the Cell Line and Protein
Cell Line ID: CL000023 , BTI-Tn-5B1-4
 Cell Line Info 
Synonyms
BTI-TN-5B1-4
BTI-TN5B1-4
BTI-Tn5B14
BTI-Tn 5B1-4
Tn-5B1-4
Tn 5B1-4
Tn5 B1-4
Tn5B1-4
TN5B14
TnH5
High Five
High 5
High-5
High5
Hi-five
Hi-5
Hi5
Tn-5
Category Spontaneously immortalized cell line
Organism
Trichoplusia ni (Cabbage looper)
Cellosaurus ID
CVCL_C190
Protein ID: PT01020 , Beta-secretase 1
 Protein Info 
Gene Name BACE1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P56817
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000023
 Cell Line Info 
 Protein ID: PT01020
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0393978
 Compound Info 
3-N-[(2S,3S,5R)-3-amino-5-[(4-fluorophenyl)carbamoyl]-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C33H41FN4O3
  1
1
Ki = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0375976
 Compound Info 
3-N-[(2S,3S,5R)-3-amino-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C39H53N5O4
  1
1
Ki = 33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381466
 Compound Info 
3-N-[(1R,3S,4S)-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H54N4O5
  1
1
Ki = 71 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0375975
 Compound Info 
3-N-[(1R,3S,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H55N5O4
  1
1
Ki = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393976
 Compound Info 
3-N-[(1R,3S,4S)-1-[(4-fluorophenyl)carbamoyl]-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C30H42FN3O4
  1
1
Ki = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0505665
 Compound Info 
3-N-[(1R,3S,4S)-3-amino-1-[(4-fluorophenyl)carbamoyl]-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C30H43FN4O3
  1
1
Ki = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419596
 Compound Info 
3-N-[(1R,3R,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide
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C36H55N5O4
  1
1
Ki = 11300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS