| Compound ID |
Compound Name |
Compound Formula |
|
CP0402632
|
US9427442, 14
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|
C27H26F6N4O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0552247
|
US9427442, 7
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|
C30H31F5N4O4
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0561236
|
US9427442, 11
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|
C28H28F6N4O3
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0556713
|
US9427442, 1
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|
C28H29F5N4O3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0561154
|
US9427442, 19
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|
C26H25F7N4O3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0561238
|
US9427442, 13
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|
C27H26ClF5N4O3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0515744
|
US9427442, 23
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|
C26H25ClF6N4O3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0539483
|
US9427442, 9
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|
C28H28F6N4O3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0419462
|
US9427442, 15
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|
C27H27F5N4O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0518667
|
US9427442, 8
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|
C28H29F5N4O4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0556307
|
US9427442, 12
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|
C30H31F5N4O3
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0529363
|
US9427442, 10
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|
C28H28ClF5N4O3
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0539484
|
US9427442, 24
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|
C26H26ClF5N4O3
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0561237
|
US9427442, 2
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|
C29H31F5N4O4
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0419464
|
US9427442, 5
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|
C28H28ClF5N4O3
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0402631
|
US9427442, 3
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|
C31H32F6N4O4
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0486300
|
US9427442, 22
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|
C26H25ClF6N4O3
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0519679
|
US9427442, 18
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|
C25H25F5N4O3
|
1
|
| 1 |
IC50 = 10.8 nM
|
|
|
|
CP0466215
|
US9427442, 17
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|
C26H28F4N4O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0428820
|
US9273014, Comparative Compound 48
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|
C29H36N4O3
|
1
|
| 1 |
IC50 = 12.5 nM
|
|
|
|
CP0412022
|
US9273014, Comparative Compound 47
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|
C28H35ClN4O3
|
1
|
| 1 |
IC50 = 13.5 nM
|
|
|
|
CP0553703
|
US9427442, 21
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|
C27H29F5N4O4
|
1
|
| 1 |
IC50 = 13.8 nM
|
|
|
|
CP0561153
|
US9427442, 16
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|
C25H27F4N5O4
|
1
|
| 1 |
IC50 = 15.4 nM
|
|
|
|
CP0486299
|
US9427442, 20
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|
C25H25ClF4N4O3
|
1
|
| 1 |
IC50 = 16.5 nM
|
|
|
|
CP0561235
|
US9427442, 6
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|
C26H25F5N4O3
|
1
|
| 1 |
IC50 = 18.9 nM
|
|
|
|
CP0419410
|
US9427442, 25
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|
C28H30F4N4O3
|
1
|
| 1 |
IC50 = 20.1 nM
|
|
|
|
CP0537195
|
US9427442, 4
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|
C29H29ClF6N4O3
|
1
|
| 1 |
IC50 = 21.2 nM
|
|
|
|
CP0004510
|
US9273014, Comparative Compound 45
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|
C27H34N4O3
|
1
|
| 1 |
IC50 = 48.3 nM
|
|
|
|
CP0491589
|
US9273014, Comparative Compound 46
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|
C27H31ClN4O3
|
1
|
| 1 |
IC50 = 74.5 nM
|
|
|
