| Compound ID |
Compound Name |
Compound Formula |
|
CP0093591
|
(2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
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|
C29H38O4
|
2
|
| 1 |
EC50 = 1100 nM
|
|
|
| 2 |
EC50 = 2600 nM
|
|
|
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CP0439330
|
3-(benzo[d]thiazol-2-yl)-1-isobutyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C17H16N6O2S
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0418141
|
1-butyl-6-methyl-3-(thiazol-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C13H14N6O2S
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0429671
|
3-(benzo[d]thiazol-2-yl)-1-butyl-6-methylpyrimido[4,5-c]pyridazine-5,7(1H,6H)-dione
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|
C17H16N6O2S
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0439328
|
3-(benzo[d]thiazol-2-yl)-1-isopentyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C18H18N6O2S
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0506355
|
1-butyl-6-methyl-3-(quinolin-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C19H18N6O2
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0474640
|
3-(benzo[d]thiazol-2-yl)-1-benzyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C20H14N6O2S
|
1
|
| 1 |
EC50 = 4100 nM
|
|
|
|
CP0209125
|
1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
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|
C12H11N5O2S
|
1
|
| 1 |
EC50 = 5100 nM
|
|
|
|
CP0496181
|
1-butyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C13H15N7O2
|
1
|
| 1 |
EC50 = 7700 nM
|
|
|
|
CP0429669
|
1-butyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
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|
C15H17N5O3S
|
1
|
| 1 |
EC50 = 8600 nM
|
|
|
|
CP0514658
|
1-butyl-6-methyl-3-(5-methylfuran-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C15H17N5O3
|
1
|
| 1 |
EC50 = 9900 nM
|
|
|
|
CP0431034
|
1-butyl-6-methyl-3-(5-methylfuran-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
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|
C15H17N5O4
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0431031
|
1-ethyl-3-(furan-2-yl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C12H11N5O3
|
1
|
| 1 |
EC50 = 10100 nM
|
|
|
|
CP0496180
|
1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
Show/Hide
|
C13H13N5O3S
|
1
|
| 1 |
EC50 = 11600 nM
|
|
|
|
CP0509654
|
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)benzo[e][1,3]benzoxazole-2-carboximidoyl chloride
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|
C20H22ClN3O3
|
1
|
| 1 |
EC50 = 12100 nM
|
|
|
|
CP0407549
|
(2Z)-N-[3-[cyclopropylmethyl(propan-2-yl)amino]-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C18H24ClN3O3
|
1
|
| 1 |
EC50 = 12400 nM
|
|
|
|
CP0401009
|
3-(benzo[d]thiazol-2-yl)-1-(4-fluorobenzyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C20H13FN6O2S
|
1
|
| 1 |
EC50 = 14000 nM
|
|
|
|
CP0401010
|
1-butyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C16H17N5O2
|
1
|
| 1 |
EC50 = 14800 nM
|
|
|
|
CP0429670
|
1-butyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
Show/Hide
|
C14H16N6O3
|
1
|
| 1 |
EC50 = 14900 nM
|
|
|
|
CP0407550
|
(2Z)-N-[3-[tert-butyl(propan-2-yl)amino]-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C18H26ClN3O3
|
1
|
| 1 |
EC50 = 16600 nM
|
|
|
|
CP0496196
|
1-butyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C15H17N5O2S
|
1
|
| 1 |
EC50 = 16800 nM
|
|
|
|
CP0454257
|
1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
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|
C13H13N5O2S
|
1
|
| 1 |
EC50 = 17300 nM
|
|
|
|
CP0474588
|
(2Z)-N-[3-(3,5-dimethylpiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C18H24ClN3O3
|
1
|
| 1 |
EC50 = 17400 nM
|
|
|
|
CP0407534
|
7-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
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|
C16H19ClFN3O3
|
1
|
| 1 |
EC50 = 18500 nM
|
|
|
|
CP0506150
|
4-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
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|
C16H19ClFN3O3
|
1
|
| 1 |
EC50 = 20200 nM
|
|
|
|
CP0431030
|
1-ethyl-6-methyl-3-(5-methylfuran-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
Show/Hide
|
C13H13N5O4
|
1
|
| 1 |
EC50 = 20600 nM
|
|
|
|
CP0498728
|
(2Z)-N-[3-(dibutylamino)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C19H28ClN3O3
|
1
|
| 1 |
EC50 = 20900 nM
|
|
|
|
CP0524220
|
5-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C16H19Cl2N3O3
|
1
|
| 1 |
EC50 = 20900 nM
|
|
|
|
CP0504000
|
(2Z)-N-[3-[3-fluoropropyl(propan-2-yl)amino]-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C17H23ClFN3O3
|
1
|
| 1 |
EC50 = 22800 nM
|
|
|
|
CP0387577
|
6-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C16H19Cl2N3O3
|
1
|
| 1 |
EC50 = 22900 nM
|
|
|
|
CP0427352
|
(2Z)-N-[3-[ethyl(propyl)amino]-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C16H22ClN3O3
|
1
|
| 1 |
EC50 = 23000 nM
|
|
|
|
CP0503992
|
(2Z)-N-[3-(dipropylamino)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C17H24ClN3O3
|
1
|
| 1 |
EC50 = 23900 nM
|
|
|
|
CP0919772
|
N-(2-hydroxy-3-(isopropyl(propyl)amino)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C17H24ClN3O3
|
1
|
| 1 |
EC50 = 24100 nM
|
|
|
|
CP0431038
|
1-ethyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
Show/Hide
|
C12H12N6O3
|
1
|
| 1 |
EC50 = 24700 nM
|
|
|
|
CP0387580
|
(2Z)-N-[3-[di(propan-2-yl)amino]-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C17H24ClN3O3
|
1
|
| 1 |
EC50 = 25500 nM
|
|
|
|
CP0372549
|
(2Z)-N-[3-(diethylamino)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
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|
C15H20ClN3O3
|
1
|
| 1 |
EC50 = 27100 nM
|
|
|
|
CP0471685
|
(Z,2R)-6-(1,3-benzoxazol-2-yl)-6-chloro-1-[propan-2-yl(propyl)amino]hex-5-en-2-ol
Show/Hide
|
C19H27ClN2O2
|
1
|
| 1 |
EC50 = 28600 nM
|
|
|
|
CP0509635
|
(2Z)-N-[2-hydroxy-3-[2-hydroxyethyl(propan-2-yl)amino]propoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C16H22ClN3O4
|
1
|
| 1 |
EC50 = 28700 nM
|
|
|
|
CP0514117
|
6-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C16H19ClFN3O3
|
1
|
| 1 |
EC50 = 29400 nM
|
|
|
|
CP0427355
|
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-6-methyl-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C17H22ClN3O3
|
1
|
| 1 |
EC50 = 31000 nM
|
|
|
|
CP0504815
|
(Z,2S)-6-(1,3-benzoxazol-2-yl)-6-chloro-1-[propan-2-yl(propyl)amino]hex-5-en-2-ol
Show/Hide
|
C19H27ClN2O2
|
1
|
| 1 |
EC50 = 31900 nM
|
|
|
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CP0407532
|
(2Z)-N-[3-(2,6-dimethylpiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C18H24ClN3O3
|
1
|
| 1 |
EC50 = 32400 nM
|
|
|
|
CP0498237
|
1-ethyl-6-methyl-3-(1H-pyrrol-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Show/Hide
|
C12H12N6O2
|
1
|
| 1 |
EC50 = 35000 nM
|
|
|
|
CP0398971
|
1-ethyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Show/Hide
|
C11H11N7O2
|
1
|
| 1 |
EC50 = 39800 nM
|
|
|
|
CP0431039
|
3-(1H-benzo[d]imidazol-2-yl)-1-butyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Show/Hide
|
C17H17N7O2
|
1
|
| 1 |
EC50 = 40800 nM
|
|
|
|
CP0438801
|
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-5-methyl-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C17H22ClN3O3
|
1
|
| 1 |
EC50 = 41600 nM
|
|
|
|
CP0506151
|
6-(N,N-dimethylsulfamoyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C18H25ClN4O5S
|
1
|
| 1 |
EC50 = 41600 nM
|
|
|
|
CP0498383
|
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C16H20ClN3O3
|
1
|
| 1 |
EC50 = 41700 nM
|
|
|
|
CP0407536
|
5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C18H24ClN3O5S
|
1
|
| 1 |
EC50 = 42900 nM
|
|
|
|
CP0491210
|
1-ethyl-6-methyl-3-(5-methylfuran-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Show/Hide
|
C13H13N5O3
|
1
|
| 1 |
EC50 = 46300 nM
|
|
|
|
CP0407533
|
5-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
Show/Hide
|
C16H19ClFN3O3
|
1
|
| 1 |
EC50 = 51300 nM
|
|
|
|
CP0427354
|
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-1,3-benzothiazole-2-carboximidoyl chloride
Show/Hide
|
C16H20ClN3O2S
|
1
|
| 1 |
EC50 = 52600 nM
|
|
|
|
CP0498384
|
(2Z)-N-[3-(3-fluoropiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
Show/Hide
|
C16H19ClFN3O3
|
1
|
| 1 |
EC50 = 52600 nM
|
|
|
|
CP0504814
|
(2Z)-N-(2-hydroxy-3-pyrrolidin-1-ylpropoxy)-1,3-benzothiazole-2-carboximidoyl chloride
Show/Hide
|
C15H18ClN3O2S
|
1
|
| 1 |
EC50 = 62800 nM
|
|
|
